Suicide inactivation of the E. coli O6-methylguanine-DNA methyltransferase
about
The base excision repair enzyme MED1 mediates DNA damage response to antitumor drugs and is associated with mismatch repair system integrityMethylator-induced, mismatch repair-dependent G2 arrest is activated through Chk1 and Chk2Methyl phosphotriesters in alkylated DNA are repaired by the Ada regulatory protein of E. coliMolecular mechanisms of the whole DNA repair system: a comparison of bacterial and eukaryotic systemsCrystal structure of a suicidal DNA repair protein: the Ada O6-methylguanine-DNA methyltransferase from E. coliRegulatory responses of the adaptive response to alkylation damage: a simple regulon with complex regulatory featuresA second DNA methyltransferase repair enzyme in Escherichia coli.DNA methylation profiles of primary colorectal carcinoma and matched liver metastasis.Homologous recombination prevents methylation-induced toxicity in Escherichia coli.Formation of a covalent complex between methylguanine methyltransferase and DNA via disulfide bond formation between the active site cysteine and a thiol-containing analog of guanine.Bacillus subtilis gene coding for constitutive O6-methylguanine-DNA alkyltransferase.Construction and characterization of mutants of Salmonella typhimurium deficient in DNA repair of O6-methylguanineAlternative pathways for the in vivo repair of O6-alkylguanine and O4-alkylthymine in Escherichia coli: the adaptive response and nucleotide excision repair.Rapid, large-scale purification and characterization of 'Ada protein' (O6 methylguanine-DNA methyltransferase) of E. coli.New method for gene disruption in Salmonella typhimurium: construction and characterization of an ada-deletion derivative of Salmonella typhimurium TA1535.Cloning and characterization of the Salmonella typhimurium ada gene, which encodes O6-methylguanine-DNA methyltransferaseSaturation of mismatch repair in the mutD5 mutator strain of Escherichia coli.Characterization of the major DNA repair methyltransferase activity in unadapted Escherichia coli and identification of a similar activity in Salmonella typhimurium.Construction and characterization of extrachromosomal probes for mutagenesis by carcinogens: site-specific incorporation of O6-methylguanine into viral and plasmid genomes.Direct reversal of DNA alkylation damage.Exonuclease 1 (Exo1) is required for activating response to S(N)1 DNA methylating agents.Mutagenesis and inducible responses to deoxyribonucleic acid damage in Escherichia coli.In vivo mutagenesis by O6-methylguanine built into a unique site in a viral genomeActive site and complete sequence of the suicidal methyltransferase that counters alkylation mutagenesisO6-Alkylguanine-DNA alkyltransferase activity correlates with the therapeutic response of human rhabdomyosarcoma xenografts to 1-(2-chloroethyl)-3-(trans-4-methylcyclohexyl)-1-nitrosourea.Multifaceted roles of alkyltransferase and related proteins in DNA repair, DNA damage, resistance to chemotherapy, and research tools.My journey to DNA repair.DNA-binding mechanism of the Escherichia coli Ada O(6)-alkylguanine-DNA alkyltransferase.The 1987 Walter Hubert lecture. Regulation and deficiencies in DNA repair.An alkB gene homolog is differentially transcribed during the Caulobacter crescentus cell cycle.A weak adaptive response to alkylation damage in Salmonella typhimurium.Mutant Escherichia coli Ada proteins simultaneously defective in the repair of O6-methylguanine and in gene activation.Cross-linking of DNA induced by chloroethylnitrosourea is presented by O6-methylguanine-DNA methyltransferaseInteraction of human and bacterial AlkB proteins with DNA as probed through chemical cross-linking studies.Organization of the BcgI restriction-modification protein for the cleavage of eight phosphodiester bonds in DNA.Inducible repair of O-alkylated DNA pyrimidines in Escherichia coli.Induction of resistance to alkylating agents in E. coli: the ada+ gene product serves both as a regulatory protein and as an enzyme for repair of mutagenic damage.The Comparative Genomics and Phylogenomics of Leishmania amazonensis Parasite.Phosphorylation of methylated-DNA-protein-cysteine S-methyltransferase at serine-204 significantly increases its resistance to proteolytic digestion.Extrachromosomal probes for mutagenesis by carcinogens: studies on the mutagenic activity of O6-methylguanine built into a unique site in a viral genome.
P2860
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P2860
Suicide inactivation of the E. coli O6-methylguanine-DNA methyltransferase
description
1982 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
1982 թվականի հունվարին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 1982
@ast
scientific journal article
@en
vedecký článok (publikovaný 1982/01/01)
@sk
vědecký článek publikovaný v roce 1982
@cs
wetenschappelijk artikel (gepubliceerd op 1982/01/01)
@nl
wissenschaftlicher Artikel
@de
наукова стаття, опублікована в січні 1982
@uk
مقالة علمية (نشرت عام 1982)
@ar
name
Suicide inactivation of the E. coli O6-methylguanine-DNA methyltransferase
@ast
Suicide inactivation of the E. coli O6-methylguanine-DNA methyltransferase
@en
Suicide inactivation of the E. coli O6-methylguanine-DNA methyltransferase
@nl
type
label
Suicide inactivation of the E. coli O6-methylguanine-DNA methyltransferase
@ast
Suicide inactivation of the E. coli O6-methylguanine-DNA methyltransferase
@en
Suicide inactivation of the E. coli O6-methylguanine-DNA methyltransferase
@nl
prefLabel
Suicide inactivation of the E. coli O6-methylguanine-DNA methyltransferase
@ast
Suicide inactivation of the E. coli O6-methylguanine-DNA methyltransferase
@en
Suicide inactivation of the E. coli O6-methylguanine-DNA methyltransferase
@nl
P2860
P921
P1433
P1476
Suicide inactivation of the E. coli O6-methylguanine-DNA methyltransferase
@en
P2093
P2860
P304
P356
10.1002/J.1460-2075.1982.TB01323.X
P407
P577
1982-01-01T00:00:00Z