Chemoproteomic profiling reveals that cathepsin D off-target activity drives ocular toxicity of β-secretase inhibitors
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Physiological Functions of the β-Site Amyloid Precursor Protein Cleaving Enzyme 1 and 2The BACE1 inhibitor verubecestat (MK-8931) reduces CNS β-amyloid in animal models and in Alzheimer's disease patients.BACE1 Function and Inhibition: Implications of Intervention in the Amyloid Pathway of Alzheimer's Disease Pathology.Proteome-wide Map of Targets of T790M-EGFR-Directed Covalent Inhibitors.The 13th Winter Conference on Medicinal and Bioorganic Chemistry.The BACE-1 inhibitor CNP520 for prevention trials in Alzheimer's disease
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Chemoproteomic profiling reveals that cathepsin D off-target activity drives ocular toxicity of β-secretase inhibitors
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2016 nî lūn-bûn
@nan
2016 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2016 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2016年の論文
@ja
2016年論文
@yue
2016年論文
@zh-hant
2016年論文
@zh-hk
2016年論文
@zh-mo
2016年論文
@zh-tw
2016年论文
@wuu
name
Chemoproteomic profiling revea ...... city of β-secretase inhibitors
@ast
Chemoproteomic profiling revea ...... city of β-secretase inhibitors
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type
label
Chemoproteomic profiling revea ...... city of β-secretase inhibitors
@ast
Chemoproteomic profiling revea ...... city of β-secretase inhibitors
@en
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Chemoproteomic profiling revea ...... city of β-secretase inhibitors
@ast
Chemoproteomic profiling revea ...... city of β-secretase inhibitors
@en
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Chemoproteomic profiling revea ...... city of β-secretase inhibitors
@en
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Andrea M Zuhl
Brian T O'Neill
Charles E Nolan
Cheng Chang
Christopher Houle
Christopher W Am Ende
Claude Ambroise
David A Karanian
David R Riddell
Douglas S Johnson
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P2888
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10.1038/NCOMMS13042
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P577
2016-10-11T00:00:00Z
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1038226015