Structure-Based Design of an in Vivo Active Selective BRD9 Inhibitor - Wikidata - wikimedia - TriplyDB

Structure-Based Design of an in Vivo Active Selective BRD9 Inhibitor

Structure-Based Design of an in Vivo Active Selective BRD9 Inhibitor

http://www.wikidata.org/entity/Q28829832

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NMR Fragment Screening Hit Induces Plasticity of BRD7/9 Bromodomains Sensitivity and engineered resistance of myeloid leukemia cells to BRD9 inhibition Targeting the Bromome: are we there yet?Epigenetic stress responses induce muscle stem-cell ageing by Hoxa9 developmental signals.Benzoisoquinolinediones as Potent and Selective Inhibitors of BRPF2 and TAF1/TAF1L Bromodomains Effect of BET Missense Mutations on Bromodomain Function, Inhibitor Binding and Stability.Establishing a reliable framework for harnessing the creative power of the scientific crowd Discovery of a PCAF Bromodomain Chemical Probe.Selective targeting of Bromodomains of the Bromodomain-PHD Fingers family impairs osteoclast differentiation.Selective targeting of epigenetic reader domains.Bromodomains in Protozoan Parasites: Evolution, Function, and Opportunities for Drug Development.Selectivity on-target of bromodomain chemical probes by structure-guided medicinal chemistry and chemical biology.Bromodomain inhibitors and cancer therapy: From structures to applications.Mammalian SWI/SNF complexes in cancer: emerging therapeutic opportunities.Chemical modulators for epigenome reader domains as emerging epigenetic therapies for cancer and inflammation.BRD9 Inhibition, Alone or in Combination with Cytostatic Compounds as a Therapeutic Approach in Rhabdoid Tumors.Paramagnetic relaxation enhancement for protein-observed 19F NMR as an enabling approach for efficient fragment screening.Chemical probes and inhibitors of bromodomains outside the BET family.Target validation: Switching domains.Degradation of the BAF Complex Factor BRD9 by Heterobifunctional Ligands.Glioma tumor suppressor candidate region gene 1 (GLTSCR1) and its paralog GLTSCR1-like form SWI/SNF chromatin remodeling subcomplexes.Vitamin D Switches BAF Complexes to Protect β Cells.Discovery of a PCAF Bromodomain Chemical Probe

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P2860

Structure-Based Design of an in Vivo Active Selective BRD9 Inhibitor

http://www.wikidata.org/entity/Q28829832

description

2016 nî lūn-bûn

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2016 թուականի Մայիսին հրատարակուած գիտական յօդուած

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2016 թվականի մայիսին հրատարակված գիտական հոդված

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2016年の論文

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2016年論文

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2016年論文

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2016年論文

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2016年論文

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2016年論文

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2016年论文

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Structure-Based Design of an in Vivo Active Selective BRD9 Inhibitor

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Structure-Based Design of an in Vivo Active Selective BRD9 Inhibitor

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Structure-Based Design of an in Vivo Active Selective BRD9 Inhibitor

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Structure-Based Design of an in Vivo Active Selective BRD9 Inhibitor

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Structure-Based Design of an in Vivo Active Selective BRD9 Inhibitor

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Structure-Based Design of an in Vivo Active Selective BRD9 Inhibitor

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ACS.JMEDCHEM.5B01865

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Journal of Medicinal Chemistry

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Structure-Based Design of an in Vivo Active Selective BRD9 Inhibitor

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Andreas Zoephel

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Anja F Hohmann

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Catherine Rogers

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Christopher R Vakoc

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Cynthia Tallant

http://www.w3.org/2001/XMLSchema#string

Darryl McConnell

http://www.w3.org/2001/XMLSchema#string

Dennis Fiegen

http://www.w3.org/2001/XMLSchema#string

Dirk Kessler

http://www.w3.org/2001/XMLSchema#string

Gerd Bader

http://www.w3.org/2001/XMLSchema#string

Guido Boehmelt

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P2860

Histone recognition and large-scale structural analysis of the human bromodomain family

CECR2, a protein involved in neurulation, forms a novel chromatin remodeling complex with SNF2L

Open access chemical probes for epigenetic targets

Discovery of I-BRD9, a Selective Cell Active Chemical Probe for Bromodomain Containing Protein 9 Inhibition

Nucleosome mobilization catalysed by the yeast SWI/SNF complex

Glide: a new approach for rapid, accurate docking and scoring. 1. Method and assessment of docking accuracy

LP99: Discovery and Synthesis of the First Selective BRD7/9 Bromodomain Inhibitor

Strain-specific modifier genes of Cecr2-associated exencephaly in mice: genetic analysis and identification of differentially expressed candidate genes

Polybromo-associated BRG1-associated factor components BRD7 and BAF180 are critical regulators of p53 required for induction of replicative senescence

Interactions with aromatic rings in chemical and biological recognition.

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10

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59

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Susanne Müller

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2016-05-26T00:00:00Z

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26914985

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