ATM- and cell cycle-dependent regulation of ATR in response to DNA double-strand breaks - Wikidata - wikimedia - TriplyDB

ATM- and cell cycle-dependent regulation of ATR in response to DNA double-strand breaks

ATM- and cell cycle-dependent regulation of ATR in response to DNA double-strand breaks

http://www.wikidata.org/entity/Q29614215

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Chk1 suppressed cell death Human single-stranded DNA binding proteins are essential for maintaining genomic stability Phosphorylation: the molecular switch of double-strand break repair P90 RSK arranges Chk1 in the nucleus for monitoring of genomic integrity during cell proliferation The F box protein Fbx6 regulates Chk1 stability and cellular sensitivity to replication stress RAD51C facilitates checkpoint signaling by promoting CHK2 phosphorylation MRE11-RAD50-NBS1 is a critical regulator of FANCD2 stability and function during DNA double-strand break repair CDK targeting of NBS1 promotes DNA-end resection, replication restart and homologous recombination Rad17 recruits the MRE11-RAD50-NBS1 complex to regulate the cellular response to DNA double-strand breaks Rad18 regulates DNA polymerase kappa and is required for recovery from S-phase checkpoint-mediated arrest Cyclin-dependent kinase inhibitor therapy for hematologic malignancies 53BP1 loss rescues BRCA1 deficiency and is associated with triple-negative and BRCA-mutated breast cancers DNA resection in eukaryotes: deciding how to fix the break Dynamics of DNA damage response proteins at DNA breaks: a focus on protein modifications Targeting ATR and Chk1 kinases for cancer treatment: a new model for new (and old) drugs Mre11-Rad50-Nbs1-dependent processing of DNA breaks generates oligonucleotides that stimulate ATM activity Human CtIP promotes DNA end resection ATM and Artemis promote homologous recombination of radiation-induced DNA double-strand breaks in G2 Essential role for DNA-PKcs in DNA double-strand break repair and apoptosis in ATM-deficient lymphocytes Cep164 is a mediator protein required for the maintenance of genomic stability through modulation of MDC1, RPA, and CHK1 Claspin operates downstream of TopBP1 to direct ATR signaling towards Chk1 activation Rapid activation of ATR by ionizing radiation requires ATM and Mre11 Trial Watch: Targeting ATM-CHK2 and ATR-CHK1 pathways for anticancer therapy DNA Damage Response in Hematopoietic Stem Cell Ageing Targeting the Checkpoint to Kill Cancer Cells BRCA Mutations, DNA Repair Deficiency, and Ovarian Aging Nucleases in homologous recombination as targets for cancer therapy Targeting ATM-deficient CLL through interference with DNA repair pathways Modulation of DNA damage and repair pathways by human tumour viruses Genotoxic anti-cancer agents and their relationship to DNA damage, mitosis, and checkpoint adaptation in proliferating cancer cells Replication protein A prevents promiscuous annealing between short sequence homologies: Implications for genome integrity Multiple cellular mechanisms prevent chromosomal rearrangements involving repetitive DNA Structural and functional analysis of the Crb2-BRCT2 domain reveals distinct roles in checkpoint signaling and DNA damage repair End-resection at DNA double-strand breaks in the three domains of life Therapeutic targeting of a robust non-oncogene addiction to PRKDC in ATM-defective tumors.Dual role for Saccharomyces cerevisiae Tel1 in the checkpoint response to double-strand breaks.Cell cycle regulation of DNA double-strand break end resection by Cdk1-dependent Dna2 phosphorylation.Balancing self-renewal against genome preservation in stem cells: How do they manage to have the cake and eat it too?DNA damage control: regulation and functions of checkpoint kinase 1 Ubiquitylation, neddylation and the DNA damage response

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ATM- and cell cycle-dependent regulation of ATR in response to DNA double-strand breaks

http://www.wikidata.org/entity/Q29614215

description

2006 nî lūn-bûn

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2006 թուականի Յունուարին հրատարակուած գիտական յօդուած

@hyw

2006 թվականի հունվարին հրատարակված գիտական հոդված

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2006年の論文

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2006年論文

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2006年論文

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2006年論文

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2006年論文

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2006年論文

@zh-tw

2006年论文

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name

ATM- and cell cycle-dependent regulation of ATR in response to DNA double-strand breaks

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ATM- and cell cycle-dependent regulation of ATR in response to DNA double-strand breaks

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type

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ATM- and cell cycle-dependent regulation of ATR in response to DNA double-strand breaks

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ATM- and cell cycle-dependent regulation of ATR in response to DNA double-strand breaks

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ATM- and cell cycle-dependent regulation of ATR in response to DNA double-strand breaks

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ATM- and cell cycle-dependent regulation of ATR in response to DNA double-strand breaks

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P1433

Nature Cell Biology

P1476

ATM- and cell cycle-dependent regulation of ATR in response to DNA double-strand breaks

@en

P2093

Ali Jazayeri

http://www.w3.org/2001/XMLSchema#string

Claudia Lukas

http://www.w3.org/2001/XMLSchema#string

Graeme C M Smith

http://www.w3.org/2001/XMLSchema#string

Jacob Falck

http://www.w3.org/2001/XMLSchema#string

Jiri Bartek

http://www.w3.org/2001/XMLSchema#string

Jiri Lukas

http://www.w3.org/2001/XMLSchema#string

P2860

ATM phosphorylates p95/nbs1 in an S-phase checkpoint pathway

ATM-dependent phosphorylation of nibrin in response to radiation exposure

SMC1 is a downstream effector in the ATM/NBS1 branch of the human S-phase checkpoint

ATM activation by DNA double-strand breaks through the Mre11-Rad50-Nbs1 complex

CDK-dependent phosphorylation of BRCA2 as a regulatory mechanism for recombinational repair

The 3' to 5' exonuclease activity of Mre 11 facilitates repair of DNA double-strand breaks

Interaction between human MCM7 and Rad17 proteins is required for replication checkpoint signaling

Nuclease activities in a complex of human recombination and DNA repair factors Rad50, Mre11, and p95

The cell-cycle checkpoint kinase Chk1 is required for mammalian homologous recombination repair

ATR-mediated checkpoint pathways regulate phosphorylation and activation of human Chk1

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37-45

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scholarly article

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1447895

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10.1038/NCB1337

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P433

1

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8

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Stephen P Jackson

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2005-12-04T00:00:00Z

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7441269

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1029720893

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16327781

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