Persistent initiation of DNA replication and chromatin-bound MCM proteins during the cell cycle in cdc6 mutants
about
The Orc4p and Orc5p subunits of the Xenopus and human origin recognition complex are related to Orc1p and Cdc6pThe dhfr oribeta-binding protein RIP60 contains 15 zinc fingers: DNA binding and looping by the central three fingers and an associated proline-rich regionPR48, a novel regulatory subunit of protein phosphatase 2A, interacts with Cdc6 and modulates DNA replication in human cellsA WD-repeat protein stabilizes ORC binding to chromatinHuman Mcm proteins at a replication origin during the G1 to S phase transitionIdentification of a novel MCM3-associated protein that facilitates MCM3 nuclear localizationChromatin association of human origin recognition complex, cdc6, and minichromosome maintenance proteins during the cell cycle: assembly of prereplication complexes in late mitosisCdc6 protein causes premature entry into S phase in a mammalian cell-free system.Phosphorylation of mammalian CDC6 by cyclin A/CDK2 regulates its subcellular localizationSld3, which interacts with Cdc45 (Sld4), functions for chromosomal DNA replication in Saccharomyces cerevisiaeHistone sumoylation is a negative regulator in Saccharomyces cerevisiae and shows dynamic interplay with positive-acting histone modificationsAssembly of a complex containing Cdc45p, replication protein A, and Mcm2p at replication origins controlled by S-phase cyclin-dependent kinases and Cdc7p-Dbf4p kinaseMCM proteins are associated with RNA polymerase II holoenzymeBinding of cyclin-dependent kinases to ORC and Cdc6p regulates the chromosome replication cycleDNA synthesis at individual replication forks requires the essential initiation factor Cdc45pChanges in association of the Xenopus origin recognition complex with chromatin on licensing of replication originsCell cycle- and cell growth-regulated proteolysis of mammalian CDC6 is dependent on APC-CDH1Yeast cohesin complex requires a conserved protein, Eco1p(Ctf7), to establish cohesion between sister chromatids during DNA replicationATPase-dependent cooperative binding of ORC and Cdc6 to origin DNA.The replication fork: understanding the eukaryotic replication machinery and the challenges to genome duplicationMultistep regulation of DNA replication by Cdk phosphorylation of HsCdc6Localization of proteins bound to a replication origin of human DNA along the cell cycleAn essential role for Orc6 in DNA replication through maintenance of pre-replicative complexesSelective instability of Orc1 protein accounts for the absence of functional origin recognition complexes during the M-G(1) transition in mammalsEasy detection of chromatin binding proteins by the Histone Association Assay.Orc1 Binding to Mitotic Chromosomes Precedes Spatial Patterning during G1 Phase and Assembly of the Origin Recognition Complex in Human Cells.A winged helix domain in human MUS81 binds DNA and modulates the endonuclease activity of MUS81 complexesThe prefoldin bud27 mediates the assembly of the eukaryotic RNA polymerases in an rpb5-dependent manner.Global regulation of H2A.Z localization by the INO80 chromatin-remodeling enzyme is essential for genome integrityOrigin recognition complex (ORC) mediates histone 3 lysine 4 methylation through cooperation with Spp1 in Saccharomyces cerevisiae.The Hect domain E3 ligase Tom1 and the F-box protein Dia2 control Cdc6 degradation in G1 phaseActivation of ubiquitin-dependent DNA damage bypass is mediated by replication protein a.Ctf18 is required for homologous recombination-mediated double-strand break repairThe essential role of Saccharomyces cerevisiae CDC6 nucleotide-binding site in cell growth, DNA synthesis, and Orc1 association.SIZ1/SIZ2 control of chromosome transmission fidelity is mediated by the sumoylation of topoisomerase IICohesin rings devoid of Scc3 and Pds5 maintain their stable association with the DNAScm3, an essential Saccharomyces cerevisiae centromere protein required for G2/M progression and Cse4 localization.Mcm10 and the MCM2-7 complex interact to initiate DNA synthesis and to release replication factors from origins.The Rix1 (Ipi1p-2p-3p) complex is a critical determinant of DNA replication licensing independent of their roles in ribosome biogenesis.Efficient initiation of DNA replication in eukaryotes requires Dpb11/TopBP1-GINS interaction
P2860
Q22008054-08214060-AAEC-4DB9-B2A2-E371D5C5F009Q22010958-BBAD067B-C657-49E2-9279-A1EF0FF90A9DQ22011045-5839527A-726F-42C0-ABD0-6EB56500F225Q24302131-55090D75-6914-4F71-A765-778900F08B09Q24309201-7F78223D-9493-4998-9633-33B8C93DEFD5Q24336067-EF65BF7F-6A55-4E95-B16B-83379B794716Q24515107-454ACEE1-E37C-434B-9D7E-2D448321226EQ24533451-1448D43E-89A3-43AC-A7A8-C5B15D9CD733Q24533531-73F8CF85-5E50-42DA-9610-140FE0963FF5Q24535011-7FAD28EF-97D5-4238-B7C6-97C6D0A2E74DQ24545952-18AB4C2C-F4B6-4559-BDF1-CB70EF629057Q24554245-0B9ABE12-D25B-43EC-95FE-3CABB01AE0F7Q24554446-95CC2395-39E2-40B3-8706-A14696A26F8EQ24555189-94783C4F-8A4C-48FF-B85C-7E259F1B6304Q24599663-7AF35E79-E93C-4C27-8EDD-F8BF84B623C5Q24600305-1BA6E68E-AC08-4A5F-9BCE-FAD490DB2325Q24600785-FB9ADF0C-6500-466C-B216-BC3E6226D4C5Q24608777-3EFEE6EA-8903-443C-9F68-084CBF571E19Q24633457-EE29A1DE-2DD9-4F52-829A-0976EF6648D6Q24633729-693FD893-1151-4B28-B607-83D25DCBCDC6Q24656841-E61B0049-DD3C-4288-A3DF-D8D930A93F09Q24671857-599B9470-DE40-4305-9EA5-77584D2F5447Q24676407-A478A314-FD15-4C16-B336-BD60FD958947Q24685501-1504B9CB-8A28-4CF8-9674-E61540793556Q24815956-5A2A3A0D-C090-4F2B-BF6B-A6C81477F38DQ27313730-2E6F3E33-C1FC-4941-9F37-1D3B7B08370CQ27679816-51ED4173-BC42-4834-9230-7E63D97F3FFBQ27929893-1BE54F9A-5D50-48C4-B7C6-A04A3DC9438DQ27930002-7D2FABD4-AC80-4490-8FB6-E65CAD6746B6Q27930416-F4565491-E52F-43A1-9DC7-6156CE9A0E15Q27930722-EA05FA89-97BF-4E25-AF04-F2105E583D6DQ27930823-B564475B-5E69-4F05-A486-11F302974DAFQ27931105-4AAF812D-A1C0-43E2-A9F8-DDB2F008BDFCQ27931255-893B3311-8C56-4355-AC77-561D152B3453Q27931553-271FDFB9-3EE9-4FAD-A7EB-137241E49449Q27931856-984C6466-D8BB-4EB9-A2E5-6DAEB60ECBBAQ27932322-1746710C-E6ED-4352-8CEC-0D3E26CD13EFQ27932462-3BCC1CA5-FF0C-451A-95AE-87857BFD6952Q27932783-8E820DE1-D761-4B22-8F8A-6B828292E8F7Q27932850-24FBB969-043A-4E1A-811B-D6F4C562996D
P2860
Persistent initiation of DNA replication and chromatin-bound MCM proteins during the cell cycle in cdc6 mutants
description
1997 nî lūn-bûn
@nan
1997 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1997 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
name
Persistent initiation of DNA r ...... the cell cycle in cdc6 mutants
@ast
Persistent initiation of DNA r ...... the cell cycle in cdc6 mutants
@en
type
label
Persistent initiation of DNA r ...... the cell cycle in cdc6 mutants
@ast
Persistent initiation of DNA r ...... the cell cycle in cdc6 mutants
@en
prefLabel
Persistent initiation of DNA r ...... the cell cycle in cdc6 mutants
@ast
Persistent initiation of DNA r ...... the cell cycle in cdc6 mutants
@en
P2860
P3181
P356
P1433
P1476
Persistent initiation of DNA r ...... the cell cycle in cdc6 mutants
@en
P2093
P2860
P304
P3181
P356
10.1101/GAD.11.24.3375
P407
P577
1997-12-15T00:00:00Z