A mammalian cell cycle checkpoint pathway utilizing p53 and GADD45 is defective in ataxia-telangiectasia
about
GADD45 induction of a G2/M cell cycle checkpointEffects of mutant p53 expression on human 15-lipoxygenase-promoter activity and murine 12/15-lipoxygenase gene expression: evidence that 15-lipoxygenase is a mutator geneThe human G2 checkpoint control protein hRAD9 is a nuclear phosphoprotein that forms complexes with hRAD1 and hHUS1Expression of BRC repeats in breast cancer cells disrupts the BRCA2-Rad51 complex and leads to radiation hypersensitivity and loss of G(2)/M checkpoint controlIsolation and characterization of a novel TP53-inducible gene, TP53TG5, which suppresses growth and shows cell cycle-dependent transition of expressionFunctional link of BRCA1 and ataxia telangiectasia gene product in DNA damage responseOpposite effect of NF-kB and c-Jun N-terminal kinase on p53-independent GADD45 induction by arseniteThe transcription factor p53: not a repressor, solely an activatorInteraction of CR6 (GADD45gamma ) with proliferating cell nuclear antigen impedes negative growth controlp53 Modulates the exonuclease activity of Werner syndrome proteinHuman SAD1 kinase is involved in UV-induced DNA damage checkpoint functionSWI/SNF complex interacts with tumor suppressor p53 and is necessary for the activation of p53-mediated transcriptionGlioma oncoprotein Bcl2L12 inhibits the p53 tumor suppressorCR6-interacting factor 1 interacts with Gadd45 family proteins and modulates the cell cycleDNA damage activates a spatially distinct late cytoplasmic cell-cycle checkpoint network controlled by MK2-mediated RNA stabilizationThe stress kinase MRK contributes to regulation of DNA damage checkpoints through a p38gamma-independent pathwayPost-transcriptional regulation of thioredoxin by the stress inducible heterogenous ribonucleoprotein A18.Identification of a novel p53 functional domain that is necessary for efficient growth suppressionHigh mobility group protein-1 (HMG-1) is a unique activator of p53A human homologue of the Schizosaccharomyces pombe rad1+ checkpoint gene encodes an exonucleaseIdentification of a human homologue of the Schizosaccharomyces pombe rad17+ checkpoint geneStimulation of p53-mediated transcriptional activation by the p53-binding proteins, 53BP1 and 53BP2Cloning and characterization of a wortmannin-sensitive human phosphatidylinositol 4-kinaseFunctional association of poly(ADP-ribose) polymerase with DNA polymerase alpha-primase complex: a link between DNA strand break detection and DNA replicationMammalian GADD34, an apoptosis- and DNA damage-inducible geneThe p53-binding protein 53BP2 also interacts with Bc12 and impedes cell cycle progression at G2/MA human homolog of the Schizosaccharomyces pombe rad9+ checkpoint control geneWip1, a novel human protein phosphatase that is induced in response to ionizing radiation in a p53-dependent mannerAdenovirus E1B 55K represses p53 activation in vitro.Phosphorylation of the replication protein A large subunit in the Saccharomyces cerevisiae checkpoint responsep53 sites acetylated in vitro by PCAF and p300 are acetylated in vivo in response to DNA damageExpression of the papillomavirus E2 protein in HeLa cells leads to apoptosisTyrosine phosphorylation of Mdm2 by c-Abl: implications for p53 regulationLoading and unloading: orchestrating centrosome duplication and spindle assembly by Ran/Crm1HRAD1 and MRAD1 encode mammalian homologues of the fission yeast rad1(+) cell cycle checkpoint control geneThe modified human DNA repair enzyme O(6)-methylguanine-DNA methyltransferase is a negative regulator of estrogen receptor-mediated transcription upon alkylation DNA damageEarly embryonic lethality in PARP-1 Atm double-mutant mice suggests a functional synergy in cell proliferation during developmentMCG10, a novel p53 target gene that encodes a KH domain RNA-binding protein, is capable of inducing apoptosis and cell cycle arrest in G(2)-MNonhomologous end joining and V(D)J recombination require an additional factorGadd45, a p53-responsive stress protein, modifies DNA accessibility on damaged chromatin
P2860
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P2860
A mammalian cell cycle checkpoint pathway utilizing p53 and GADD45 is defective in ataxia-telangiectasia
description
1992 nî lūn-bûn
@nan
1992 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
1992 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
1992年の論文
@ja
1992年論文
@yue
1992年論文
@zh-hant
1992年論文
@zh-hk
1992年論文
@zh-mo
1992年論文
@zh-tw
1992年论文
@wuu
name
A mammalian cell cycle checkpo ...... ctive in ataxia-telangiectasia
@ast
A mammalian cell cycle checkpo ...... ctive in ataxia-telangiectasia
@en
type
label
A mammalian cell cycle checkpo ...... ctive in ataxia-telangiectasia
@ast
A mammalian cell cycle checkpo ...... ctive in ataxia-telangiectasia
@en
prefLabel
A mammalian cell cycle checkpo ...... ctive in ataxia-telangiectasia
@ast
A mammalian cell cycle checkpo ...... ctive in ataxia-telangiectasia
@en
P2093
P3181
P1433
P1476
A mammalian cell cycle checkpo ...... ctive in ataxia-telangiectasia
@en
P2093
Fornace AJ Jr
Plunkett BS
el-Deiry WS
P304
P3181
P356
10.1016/0092-8674(92)90593-2
P407
P577
1992-11-13T00:00:00Z