Chemical chaperones reduce ER stress and restore glucose homeostasis in a mouse model of type 2 diabetes
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High glucose suppresses human islet insulin biosynthesis by inducing miR-133a leading to decreased polypyrimidine tract binding protein-expressionEndoplasmic reticulum stress and Parkinson's disease: the role of HRD1 in averting apoptosis in neurodegenerative diseaseA crucial role for RACK1 in the regulation of glucose-stimulated IRE1alpha activation in pancreatic beta cellsA regulatory subunit of phosphoinositide 3-kinase increases the nuclear accumulation of X-box-binding protein-1 to modulate the unfolded protein responseSCAMP5 links endoplasmic reticulum stress to the accumulation of expanded polyglutamine protein aggregates via endocytosis inhibitionClinical and experimental applications of sodium phenylbutyrateReduced histone deacetylase 7 activity restores function to misfolded CFTR in cystic fibrosisHistone deacetylase inhibitor (HDACi) suberoylanilide hydroxamic acid (SAHA)-mediated correction of α1-antitrypsin deficiencyThe role of bile after Roux-en-Y gastric bypass in promoting weight loss and improving glycaemic controlEndoplasmic reticulum stress and the inflammatory basis of metabolic diseaseBile acids in treatment of ocular diseaseBile acids: regulation of apoptosis by ursodeoxycholic acidA top-down systems biology view of microbiome-mammalian metabolic interactions in a mouse modelAntioxidant Activity of γ-Oryzanol: A Complex Network of InteractionsInsulin Is a Key Modulator of Fetoplacental Endothelium Metabolic Disturbances in Gestational Diabetes MellitusInflammation Meets Metabolic Disease: Gut Feeling Mediated by GLP-1Pharmacological Modulators of Endoplasmic Reticulum Stress in Metabolic DiseasesThe Role of Endoplasmic Reticulum Stress and Unfolded Protein Response in AtherosclerosisNew mechanisms of metformin action: Focusing on mitochondria and the gutEssential roles of four-carbon backbone chemicals in the control of metabolismPotential Bioactive Compounds from Seaweed for Diabetes ManagementEndoplasmic Reticulum Stress in the Diabetic Kidney, the Good, the Bad and the UglyProtein Folding and Mechanisms of ProteostasisProtein folding and quality control in the ERPotential roles of GPR120 and its agonists in the management of diabetesThe role of glucosamine-induced ER stress in diabetic atherogenesisEndothelial dysfunction in diabetes mellitus: possible involvement of endoplasmic reticulum stress?Treatment of nonalcoholic steatohepatitis in adults: present and futureCentral nervous system mechanisms linking the consumption of palatable high-fat diets to the defense of greater adiposityLost in translation: endoplasmic reticulum stress and the decline of β-cell health in diabetes mellitusGlutathione and mitochondriaGuards and culprits in the endoplasmic reticulum: glucolipotoxicity and β-cell failure in type II diabetesXenobiotic perturbation of ER stress and the unfolded protein responseThe unfolded protein response and diabetic retinopathyRole of lipotoxicity in endothelial dysfunctionFree Fatty acids and their metabolism affect function and survival of podocytesProtein homeostasis as a therapeutic target for diseases of protein conformationChemical and biological approaches for adapting proteostasis to ameliorate protein misfolding and aggregation diseases: progress and prognosisStress management: How the unfolded protein response impacts fatty liver diseaseNeuroinflammation in overnutrition-induced diseases
P2860
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P2860
Chemical chaperones reduce ER stress and restore glucose homeostasis in a mouse model of type 2 diabetes
description
2006 nî lūn-bûn
@nan
2006 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
Chemical chaperones reduce ER ...... mouse model of type 2 diabetes
@ast
Chemical chaperones reduce ER ...... mouse model of type 2 diabetes
@en
type
label
Chemical chaperones reduce ER ...... mouse model of type 2 diabetes
@ast
Chemical chaperones reduce ER ...... mouse model of type 2 diabetes
@en
prefLabel
Chemical chaperones reduce ER ...... mouse model of type 2 diabetes
@ast
Chemical chaperones reduce ER ...... mouse model of type 2 diabetes
@en
P2093
P2860
P921
P3181
P356
P1433
P1476
Chemical chaperones reduce ER ...... mouse model of type 2 diabetes
@en
P2093
Cem Z Görgün
Gökhan S Hotamisligil
Lale Ozcan
Masato Furuhashi
Ross O Smith
Umut Ozcan
P2860
P304
P3181
P356
10.1126/SCIENCE.1128294
P407
P577
2006-08-01T00:00:00Z