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Anaphase initiation is regulated by antagonistic ubiquitination and deubiquitination activitiesThe tumor suppressor CYLD regulates entry into mitosisThe cyclin E/Cdk2 substrate p220(NPAT) is required for S-phase entry, histone gene expression, and Cajal body maintenance in human somatic cellsFanconi anemia and the cell cycle: new perspectives on aneuploidyA murine model of neurofibromatosis type 2 that accurately phenocopies human schwannoma formationThe haploinsufficient hematopoietic microenvironment is critical to the pathological fracture repair in murine models of neurofibromatosis type 1SCFbeta-TRCP links Chk1 signaling to degradation of the Cdc25A protein phosphataseA functional genomic screen identifies a role for TAO1 kinase in spindle-checkpoint signalling.Therapeutic anti-cancer targets upstream of the proteasome.Genetic disruption of both Fancc and Fancg in mice recapitulates the hematopoietic manifestations of Fanconi anemia.Visualization of a highly organized intranuclear network of filaments in living mammalian cells.A critical role of CDKN3 in Bcr-Abl-mediated tumorigenesisCyclin E-CDK2 protein phosphorylates plant homeodomain finger protein 8 (PHF8) and regulates its function in the cell cycle.Pathophysiological role of microRNA-29 in pancreatic cancer stromaDrug discovery in the ubiquitin-proteasome system.Leukemia and chromosomal instability in aged Fancc-/- mice.Imatinib mesylate for plexiform neurofibromas in patients with neurofibromatosis type 1: a phase 2 trial.Identification and functional evaluation of cellular and viral factors involved in the alteration of nuclear architecture during herpes simplex virus 1 infection.INPP5E Preserves Genomic Stability through Regulation of Mitosis.Normal hematopoiesis and neurofibromin-deficient myeloproliferative disease require Erk.Efp: a ring of independence?Recognition of phosphodegron motifs in human cyclin E by the SCF(Fbw7) ubiquitin ligase.Chronic steroid-response pancytopenia and increased bone density due to thromboxane synthase deficiency.
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P50
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հետազոտող
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Grzegorz Nalepa
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Grzegorz Nalepa
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Grzegorz Nalepa
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Grzegorz Nalepa
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Grzegorz Nalepa
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Grzegorz Nalepa
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P106
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36845388900
P21
P31
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0000-0002-5779-9103