SCFbeta-TRCP links Chk1 signaling to degradation of the Cdc25A protein phosphatase - Wikidata - wikimedia - TriplyDB

SCFbeta-TRCP links Chk1 signaling to degradation of the Cdc25A protein phosphatase

SCFbeta-TRCP links Chk1 signaling to degradation of the Cdc25A protein phosphatase

http://www.wikidata.org/entity/Q28234989

about

Regulated degradation of the HIV-1 Vpu protein through a betaTrCP-independent pathway limits the release of viral particles A coordinated phosphorylation by Lats and CK1 regulates YAP stability through SCF(beta-TRCP)The F-box protein FBX4 targets PIN2/TRF1 for ubiquitin-mediated degradation and regulates telomere maintenance Phosphorylation by casein kinase I promotes the turnover of the Mdm2 oncoprotein via the SCF(beta-TRCP) ubiquitin ligase SCFbeta-TRCP controls clock-dependent transcription via casein kinase 1-dependent degradation of the mammalian period-1 (Per1) protein Plk1 regulates activation of the anaphase promoting complex by phosphorylating and triggering SCFbetaTrCP-dependent destruction of the APC Inhibitor Emi1 NEK11 regulates CDC25A degradation and the IR-induced G2/M checkpoint The Cdc14B-Cdh1-Plk1 axis controls the G2 DNA-damage-response checkpoint M-phase kinases induce phospho-dependent ubiquitination of somatic Wee1 by SCFbeta-TrCP The ubiquitin-specific protease USP47 is a novel beta-TRCP interactor regulating cell survival 14-3-3gamma mediates Cdc25A proteolysis to block premature mitotic entry after DNA damage Normal cell cycle and checkpoint responses in mice and cells lacking Cdc25B and Cdc25C protein phosphatases.Human Claspin works with BRCA1 to both positively and negatively regulate cell proliferation SCF(β-TRCP)-mediated degradation of NEDD4 inhibits tumorigenesis through modulating the PTEN/Akt signaling pathway The replication fork: understanding the eukaryotic replication machinery and the challenges to genome duplication Control of cell growth by the SCF and APC/C ubiquitin ligases Differential roles for checkpoint kinases in DNA damage-dependent degradation of the Cdc25A protein phosphatase Basal ubiquitin-independent internalization of interferon alpha receptor is prevented by Tyk2-mediated masking of a linear endocytic motif SCFbeta-TRCP controls oncogenic transformation and neural differentiation through REST degradation Phosphorylation-dependent ubiquitination of cyclin D1 by the SCF(FBX4-alphaB crystallin) complex Claspin operates downstream of TopBP1 to direct ATR signaling towards Chk1 activation Cdc7-Dbf4 and the human S checkpoint response to UVC Chk1-mediated phosphorylation of FANCE is required for the Fanconi anemia/BRCA pathway The Roles of NDR Protein Kinases in Hippo Signalling Targeting the Checkpoint to Kill Cancer Cells Targeting the ubiquitin pathway for cancer treatment Plk1- and beta-TrCP-dependent degradation of Bora controls mitotic progression SCF TrCP1 activates and ubiquitylates TAp63gamma Spy1 expression prevents normal cellular responses to DNA damage: inhibition of apoptosis and checkpoint activation Novel regulation of checkpoint kinase 1: Is checkpoint kinase 1 a good candidate for anti-cancer therapy?The SCF ubiquitin ligase: insights into a molecular machine Phospho-Ser/Thr-binding domains: navigating the cell cycle and DNA damage response Ubiquitin and SUMO systems in the regulation of mitotic checkpoints DNA damage response genes and the development of cancer metastasis Regulation of interleukin-10 receptor ubiquitination and stability by beta-TrCP-containing ubiquitin E3 ligase Targeting the oncogenic E3 ligase Skp2 in prostate and breast cancer cells with a novel energy restriction-mimetic agent Role of F-box protein betaTrcp1 in mammary gland development and tumorigenesis Loss of Nek11 Prevents G2/M Arrest and Promotes Cell Death in HCT116 Colorectal Cancer Cells Exposed to Therapeutic DNA Damaging Agents Regulation of postsynaptic RapGAP SPAR by Polo-like kinase 2 and the SCFbeta-TRCP ubiquitin ligase in hippocampal neurons TAZ promotes PC2 degradation through a SCFbeta-Trcp E3 ligase complex

P2860

Q21559507-3B2667B4-ECF0-421E-B681-10898B1CCF6C Q24293710-5AA5BFFA-A167-428C-A464-5EB27A523914 Q24293991-01835E1B-17F9-42BC-BCEB-1E96BED378D4 Q24295177-7118B3F2-7481-4D2A-B0C4-696EBC65607B Q24303638-7890C889-48B5-4AEE-B015-4D53C92A98AF Q24306531-48F886A0-53C5-4DCA-A58A-AE71008C59AA Q24313589-9A55690B-1F6C-4AAA-A06D-74159556C83A Q24317772-DBC27639-844B-4736-B483-5ED9383C633B Q24329203-E91E6A94-11C1-4E58-8223-43808835B487 Q24336640-C4E42052-349A-4776-AAB6-EF349E3AACBE Q24338975-0E4E8561-6C6D-4521-9C7A-96924FF0ADC0 Q24519082-83831307-5635-4BA5-BD32-1811D3820DB0 Q24564847-769D3D8D-0628-412A-9682-11407E1C3344 Q24567471-E5FF340D-D241-4EBD-AC4E-AC2DE0D13C26 Q24633729-AD6D0947-FFCB-48D0-A9DB-346A932EE1E5 Q24647543-B0A87BEA-A39A-45C0-A663-52ADFCC49D4E Q24647659-1C1E1CB8-6327-4398-9FEC-51314C8542FE Q24649769-96765CE8-4882-4072-8A0C-474C9D20F642 Q24653723-0FDCACC8-8A00-4388-9F38-BEFB0DAFACD3 Q24670129-4CDAC8A9-D1EB-4A57-A9C4-102D24E5E018 Q24670580-FE7D1B7E-9A68-438E-8FB5-1FAB65503629 Q24672815-6BB9333C-A1D4-47E1-936C-028F8C0F6EA3 Q24683360-6B87CE51-0488-40DA-A4F4-6CCCD4831164 Q26746889-3EADE4A4-4A5F-4D3E-AEF0-5D59513B62CA Q26795781-880C11BB-2F1F-450D-A41C-8F3ACC3CA24B Q26866185-8D72881D-7A6F-4078-A9F2-813C693EF62D Q28115063-992800A3-7F78-407A-B6C1-548B741167EC Q28255162-4881178F-F8D0-45CF-A9CB-A7CE842136B9 Q28261764-490E96E3-1D5D-498D-9397-BB342CBA6C1A Q28262425-F5F04E9A-2403-4E92-81F5-2D6E937A1DFF Q28279993-1B291C64-C801-433F-BF51-955DD3A7640C Q28297156-B2787683-5777-4E6C-A270-8264ECE1C649 Q28387076-0A87AEF5-E6F3-455B-BBF5-BC43C0CE8D3E Q28388312-560E3CCA-A632-4D45-AC3A-6F6D1211C2DF Q28477869-B206E3B0-3574-4AA5-8BE5-41CC1990C549 Q28484382-F951CE8F-AC14-42AA-B6DB-181733F7991C Q28508088-A3A637D8-8739-4A2A-9929-B94BE094F3C6 Q28550493-917FC49C-9769-4E8E-966B-D69BCCC20D92 Q28577634-B82859E8-891E-4548-B45B-B37C3BD6AFEE Q28588868-5BF131DB-4365-4612-A5BF-E934DBA8DA3F

P2860

SCFbeta-TRCP links Chk1 signaling to degradation of the Cdc25A protein phosphatase

http://www.wikidata.org/entity/Q28234989

description

2003 nî lūn-bûn

@nan

2003 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2003 թվականի դեկտեմբերին հրատարակված գիտական հոդված

@hy

2003年の論文

@ja

2003年論文

@yue

2003年論文

@zh-hant

2003年論文

@zh-hk

2003年論文

@zh-mo

2003年論文

@zh-tw

2003年论文

@wuu

name

SCFbeta-TRCP links Chk1 signaling to degradation of the Cdc25A protein phosphatase

@ast

SCFbeta-TRCP links Chk1 signaling to degradation of the Cdc25A protein phosphatase

@en

SCFbeta-TRCP links Chk1 signaling to degradation of the Cdc25A protein phosphatase

@nl

type

label

SCFbeta-TRCP links Chk1 signaling to degradation of the Cdc25A protein phosphatase

@ast

SCFbeta-TRCP links Chk1 signaling to degradation of the Cdc25A protein phosphatase

@en

SCFbeta-TRCP links Chk1 signaling to degradation of the Cdc25A protein phosphatase

@nl

prefLabel

SCFbeta-TRCP links Chk1 signaling to degradation of the Cdc25A protein phosphatase

@ast

SCFbeta-TRCP links Chk1 signaling to degradation of the Cdc25A protein phosphatase

@en

SCFbeta-TRCP links Chk1 signaling to degradation of the Cdc25A protein phosphatase

@nl

P1433

Q28234989-0CE18341-02D2-4434-AB4B-D58B756B0B3A

P1476

Q28234989-A177D1CB-9F12-408F-B859-114FB20CD49D

P2093

Q28234989-04173AB5-ECAD-4568-A568-61038DCE5CE1

Q28234989-2322BE40-78E2-47FB-AEB1-E5896D702BD5

Q28234989-5A55A767-45C5-4F63-84F3-D8CF01274DA4

Q28234989-A6488094-084B-4C5B-BCFE-B449E4453882

Q28234989-C82D1642-924C-47C8-B5BC-F9720953C851

P2860

Q28234989-0223BF63-F8E0-4C5F-B366-105F3585B6CC

Q28234989-02EC0925-F8D7-4517-837E-9C6E2B35DB99

Q28234989-0CF03D3E-E04A-4BAF-AE71-95B44125F3D3

Q28234989-136958DA-09E3-4EF9-AFF2-8194BC86CABA

Q28234989-1582CF9D-DE5F-4B78-BFB2-0B51924509A2

Q28234989-1765DDE8-51C4-4633-8ED2-B541A7DC37B8

Q28234989-1FA0CBC1-B40C-4279-8617-1A05DFDD56B5

Q28234989-216FB5E2-5227-41EB-96C9-672B949DA1B3

Q28234989-2CE87988-FF61-4544-B22D-6A701A6BAA2F

Q28234989-305B4709-293C-4D39-B234-99C2921F332E

P304

Q28234989-05AD0A88-C7F4-4728-91BD-AA9582237A26

P31

Q28234989-A193C2AC-B505-4499-AEC1-5A5BCADE4BC4

P3181

Q28234989-97070E5D-1EA3-436C-98B9-3B0704040CC0

P356

Q28234989-B46121E0-73B9-4615-88AD-003D6A23B321

P407

Q28234989-DCCFF345-5BA5-4F30-8D19-A73558F53893

P433

Q28234989-A686A6E9-C80D-4C4D-828F-7A17B10FEEB6

P478

Q28234989-4303D27D-5A27-4A8E-B4C2-3935B0B4BA84

P50

Q28234989-32646928-AE0C-4BC9-96DC-BF0B3B4D31DB

Q28234989-5B56C235-CD39-4427-B54D-1253C904D31E

P577

Q28234989-8D884C64-A42B-4BDF-99C2-373AE052DECA

P5875

Q28234989-37BECBC1-3B3C-40EC-96B4-41AC6DC5A085

P698

Q28234989-3F870B13-3AA8-44F8-BBE0-B48B666630CF

P932

Q28234989-3274CB23-21D8-4128-B6D9-30BE89650FC4

P3181

P356

P1433

Genes & Development

P1476

SCFbeta-TRCP links Chk1 signaling to degradation of the Cdc25A protein phosphatase

@en

P2093

J Wade Harper

http://www.w3.org/2001/XMLSchema#string

Jianping Jin

http://www.w3.org/2001/XMLSchema#string

Jun Qin

http://www.w3.org/2001/XMLSchema#string

Lai Xu

http://www.w3.org/2001/XMLSchema#string

Takahiro Shirogane

http://www.w3.org/2001/XMLSchema#string

P2860

Signal-induced ubiquitination of IkappaBalpha by the F-box protein Slimb/beta-TrCP

Linkage of ATM to cell cycle regulation by the Chk2 protein kinase

A human homologue of the checkpoint kinase Cds1 directly inhibits Cdc25 phosphatase

A family of mammalian F-box proteins

The ATM-Chk2-Cdc25A checkpoint pathway guards against radioresistant DNA synthesis

Structure of a beta-TrCP1-Skp1-beta-catenin complex: destruction motif binding and lysine specificity of the SCF(beta-TrCP1) ubiquitin ligase

Disruption of the checkpoint kinase 1/cell division cycle 25A pathway abrogates ionizing radiation-induced S and G2 checkpoints.

CDC25A phosphatase is a target of E2F and is required for efficient E2F-induced S phase

Chk1 is an essential kinase that is regulated by Atr and required for the G(2)/M DNA damage checkpoint

The SCFbeta-TRCP-ubiquitin ligase complex associates specifically with phosphorylated destruction motifs in IkappaBalpha and beta-catenin and stimulates IkappaBalpha ubiquitination in vitro

P304

3062-74

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P3181

1548126

http://www.w3.org/2001/XMLSchema#string

P356

10.1101/GAD.1157503

http://www.w3.org/2001/XMLSchema#string

P407

P433

24

http://www.w3.org/2001/XMLSchema#string

P478

17

http://www.w3.org/2001/XMLSchema#string

P50

Stephen Elledge

Grzegorz Nalepa

P577

2003-12-15T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

8954818

http://www.w3.org/2001/XMLSchema#string

P698

14681206

http://www.w3.org/2001/XMLSchema#string

P932

305258

http://www.w3.org/2001/XMLSchema#string