Molecular priming of Lyn by GPVI enables an immune receptor to adopt a hemostatic role.
about
Occlusive thrombi arise in mammals but not birds in response to arterial injury: evolutionary insight into human cardiovascular diseasePlatelet signalingThymidine Phosphorylase Participates in Platelet Signaling and Promotes ThrombosisLarge-Scale Screening of Preferred Interactions of Human Src Homology-3 (SH3) Domains Using Native Target Proteins as Affinity LigandsSH3 domain-mediated recruitment of host cell amphiphysins by alphavirus nsP3 promotes viral RNA replicationDiminished contact-dependent reinforcement of Syk activation underlies impaired thrombus growth in mice lacking Semaphorin 4D.Proteolysis of platelet receptors in humans and other species.Distinct and overlapping functional roles of Src family kinases in mouse platelets.SLAP/SLAP2 prevent excessive platelet (hem)ITAM signaling in thrombosis and ischemic stroke in mice.Lyn and PECAM-1 function as interdependent inhibitors of platelet aggregation.Platelets regulate lymphatic vascular development through CLEC-2-SLP-76 signalingThe Src family kinases and protein kinase C synergize to mediate Gq-dependent platelet activation.Lysyl oxidase is associated with increased thrombosis and platelet reactivity.Angiotensin 1-7 and Mas decrease thrombosis in Bdkrb2-/- mice by increasing NO and prostacyclin to reduce platelet spreading and glycoprotein VI activation.The future of glycoprotein VI as an antithrombotic target.Harnessing the platelet signaling network to produce an optimal hemostatic response.Src family kinases: at the forefront of platelet activationITIM receptors: more than just inhibitors of platelet activation.New Concepts and Mechanisms of Platelet Activation Signaling.Regulation of platelet activation and thrombus formation by reactive oxygen speciesSyk-dependent phosphorylation of CLEC-2: a novel mechanism of hem-immunoreceptor tyrosine-based activation motif signalingITAM receptor-mediated generation of reactive oxygen species in human platelets occurs via Syk-dependent and Syk-independent pathways.Maintenance of murine platelet homeostasis by the kinase Csk and the phosphatase CD148.Cryopreserved platelets demonstrate reduced activation responses and impaired signaling after agonist stimulation.Negative regulators of platelet activation and adhesion.TNF receptor-associated factor 4 (TRAF4) is a novel binding partner of glycoprotein Ib and glycoprotein VI in human platelets.
P2860
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P2860
Molecular priming of Lyn by GPVI enables an immune receptor to adopt a hemostatic role.
description
2009 nî lūn-bûn
@nan
2009 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
Molecular priming of Lyn by GPVI enables an immune receptor to adopt a hemostatic role.
@ast
Molecular priming of Lyn by GPVI enables an immune receptor to adopt a hemostatic role.
@en
type
label
Molecular priming of Lyn by GPVI enables an immune receptor to adopt a hemostatic role.
@ast
Molecular priming of Lyn by GPVI enables an immune receptor to adopt a hemostatic role.
@en
prefLabel
Molecular priming of Lyn by GPVI enables an immune receptor to adopt a hemostatic role.
@ast
Molecular priming of Lyn by GPVI enables an immune receptor to adopt a hemostatic role.
@en
P2093
P2860
P356
P1476
Molecular priming of Lyn by GPVI enables an immune receptor to adopt a hemostatic role.
@en
P2093
Alec A Schmaier
Jerry Ware
Karen P Fong
Keith B Neeves
Lawrence F Brass
Lori Emert-Sedlak
Mark L Kahn
Satya P Kunapuli
Scott L Diamond
Sean F Maloney
P2860
P304
21167-21172
P356
10.1073/PNAS.0906436106
P407
P577
2009-11-25T00:00:00Z