Src family kinases: at the forefront of platelet activation
about
Novel autophosphorylation sites of Src family kinases regulate kinase activity and SH2 domain-binding capacityThe Tyrosine Kinase c-Src Specifically Binds to the Active Integrin αIIbβ3 to Initiate Outside-in Signaling in PlateletsA dominant gain-of-function mutation in universal tyrosine kinase SRC causes thrombocytopenia, myelofibrosis, bleeding, and bone pathologies.Metalloproteolytic receptor shedding…platelets "acting their age".Action of Nanoparticles on Platelet Activation and Plasmatic CoagulationRuthenium-conjugated chrysin analogues modulate platelet activity, thrombus formation and haemostasis with enhanced efficacyPerspective: Tyrosine phosphatases as novel targets for antiplatelet therapy.Platelet-neutrophil interactions under thromboinflammatory conditionsRegulation of Early Steps of GPVI Signal Transduction by Phosphatases: A Systems Biology Approach.Cigarette Smoking-Associated Alterations in Serotonin/Adrenalin Signaling Pathways of PlateletsOmics for prediction of environmental health effects: Blood leukocyte-based cross-omic profiling reliably predicts diseases associated with tobacco smokingDirectly Activating the Integrin αIIbβ3 Initiates Outside-In Signaling by Causing αIIbβ3 Clustering.Blood-based omic profiling supports female susceptibility to tobacco smoke-induced cardiovascular diseases.Phosphoproteomic network analysis in the sea urchin Strongylocentrotus purpuratus reveals new candidates in egg activation.Integrin αIIbβ3 outside-in signaling.New Concepts and Mechanisms of Platelet Activation Signaling.A novel ruthenium (II)-derived organometallic compound, TQ-6, potently inhibits platelet aggregation: Ex vivo and in vivo studies.The small molecule MERTK inhibitor UNC2025 decreases platelet activation and prevents thrombosis.Comparison of Acalabrutinib, A Selective Bruton Tyrosine Kinase Inhibitor, with Ibrutinib in Chronic Lymphocytic Leukemia Cells.Maintenance of murine platelet homeostasis by the kinase Csk and the phosphatase CD148.Mucor circinelloides induces platelet aggregation through integrin αIIbβ3 and FcγRIIA.Src family kinase tyrosine phosphorylates Toll-like receptor 4 to dissociate MyD88 and Mal/Tirap, suppressing LPS-induced inflammatory responses.Cryopreserved platelets demonstrate reduced activation responses and impaired signaling after agonist stimulation.Gq pathway regulates proximal C-type lectin-like receptor-2 (CLEC-2) signaling in platelets.Plasma kallikrein enhances platelet aggregation response by subthreshold doses of ADP.Clathrin-mediated integrin αIIbβ3 trafficking controls platelet spreading.Mouse podoplanin supports adhesion and aggregation of platelets under arterial shear: A novel mechanism of haemostasis.The Yin and Yang of Tyrosine Kinase Inhibition During Experimental Polymicrobial Sepsis.Csk/CD148 and platelet SFK activation: a balancing act!Modulates Platelet Function via Impaired MAPK and PLC2 ExpressionCalcium-Dependent Src Phosphorylation and Reactive Oxygen Species Generation Are Implicated in the Activation of Human Platelet Induced by Thromboxane A2 AnalogsTyrosine Kinase Inhibitor Pazopanib Inhibits Platelet Procoagulant Activity in Renal Cell Carcinoma Patients
P2860
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P2860
Src family kinases: at the forefront of platelet activation
description
2014 nî lūn-bûn
@nan
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
2014年论文
@zh
2014年论文
@zh-cn
name
Src family kinases: at the forefront of platelet activation
@en
type
label
Src family kinases: at the forefront of platelet activation
@en
prefLabel
Src family kinases: at the forefront of platelet activation
@en
P2860
P1433
P1476
Src family kinases: at the forefront of platelet activation
@en
P2093
P2860
P304
P356
10.1182/BLOOD-2014-01-453134
P407
P577
2014-08-12T00:00:00Z