Fyn and Lyn phosphorylate the Fc receptor gamma chain downstream of glycoprotein VI in murine platelets, and Lyn regulates a novel feedback pathway
about
Differential role of glycolipid-enriched membrane domains in glycoprotein VI- and integrin-mediated phospholipase Cgamma2 regulation in plateletsThymidine Phosphorylase Participates in Platelet Signaling and Promotes ThrombosisThe tyrosine phosphatase CD148 is an essential positive regulator of platelet activation and thrombosisAn important role of the SRC family kinase Lyn in stimulating platelet granule secretionTULA-2 Protein Phosphatase Suppresses Activation of Syk through the GPVI Platelet Receptor for Collagen by Dephosphorylating Tyr(P)346, a Regulatory Site of SykG6b-B inhibits constitutive and agonist-induced signaling by glycoprotein VI and CLEC-2Molecular priming of Lyn by GPVI enables an immune receptor to adopt a hemostatic role.RhoG protein regulates glycoprotein VI-Fc receptor γ-chain complex-mediated platelet activation and thrombus formationDok-2 adaptor protein regulates the shear-dependent adhesive function of platelet integrin αIIbβ3 in miceRapid ubiquitination of Syk following GPVI activation in plateletsTyrosine kinase inhibitor-induced platelet dysfunction in patients with chronic myeloid leukemiaLyn, PKC-delta, SHIP-1 interactions regulate GPVI-mediated platelet-dense granule secretionRole of phosphoinositide 3-kinase beta in glycoprotein VI-mediated Akt activation in platelets.Pannexin- and Connexin-Mediated Intercellular Communication in Platelet Function.Distinct and overlapping functional roles of Src family kinases in mouse platelets.Lyn and PECAM-1 function as interdependent inhibitors of platelet aggregation.Signaling during platelet adhesion and activationC-type lectin like receptor 2 (CLEC-2) signals independently of lipid raft microdomains in platelets.Negative regulation of Gq-mediated pathways in platelets by G(12/13) pathways through Fyn kinase.Distinct pathways regulate Syk protein activation downstream of immune tyrosine activation motif (ITAM) and hemITAM receptors in platelets.Peptide LSARLAF induces integrin β3 dependent outside-in signaling in platelets.Ginsenoside-Rp1 inhibits platelet activation and thrombus formation via impaired glycoprotein VI signalling pathway, tyrosine phosphorylation and MAPK activation.Functions of the Lyn tyrosine kinase in health and diseaseSrc family tyrosine kinase Lyn mediates VWF/GPIb-IX-induced platelet activation via the cGMP signaling pathway.Platelet immunoreceptor tyrosine-based activation motif (ITAM) signaling and vascular integrity.Src family kinases: at the forefront of platelet activationNew Concepts and Mechanisms of Platelet Activation Signaling.Co-expression of the collagen receptors leukocyte-associated immunoglobulin-like receptor-1 and glycoprotein VI on a subset of megakaryoblastsThe C-type lectin receptors CLEC-2 and Dectin-1, but not DC-SIGN, signal via a novel YXXL-dependent signaling cascade.The heptapeptide LSARLAF mediates platelet activation through phospholipase Cgamma2 independently of glycoprotein IIb-IIIaDistinct roles of GPVI and integrin alpha(2)beta(1) in platelet shape change and aggregation induced by different collagens.Syk-dependent phosphorylation of CLEC-2: a novel mechanism of hem-immunoreceptor tyrosine-based activation motif signalingPaxillin family members function as Csk-binding proteins that regulate Lyn activity in human and murine platelets.Platelet dysfunction associated with ponatinib, a new pan BCR-ABL inhibitor with efficacy for chronic myeloid leukemia resistant to multiple tyrosine kinase inhibitor therapy.Role of the p110delta PI 3-kinase in integrin and ITAM receptor signalling in plateletsThe clinical impact of ponatinib on the risk of bleeding in patients with chronic myeloid leukemia.Maintenance of murine platelet homeostasis by the kinase Csk and the phosphatase CD148.Negative regulators of platelet activation and adhesion.Immobilized fibrinogen activates human platelets through glycoprotein VI.Possible Molecular Targets of Novel Ruthenium Complexes in Antiplatelet Therapy.
P2860
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P2860
Fyn and Lyn phosphorylate the Fc receptor gamma chain downstream of glycoprotein VI in murine platelets, and Lyn regulates a novel feedback pathway
description
2000 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2000
@ast
im Dezember 2000 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2000/12/15)
@sk
vědecký článek publikovaný v roce 2000
@cs
wetenschappelijk artikel (gepubliceerd op 2000/12/15)
@nl
наукова стаття, опублікована в грудні 2000
@uk
مقالة علمية (نشرت في 15-12-2000)
@ar
name
Fyn and Lyn phosphorylate the ...... lates a novel feedback pathway
@ast
Fyn and Lyn phosphorylate the ...... lates a novel feedback pathway
@en
Fyn and Lyn phosphorylate the ...... lates a novel feedback pathway
@nl
type
label
Fyn and Lyn phosphorylate the ...... lates a novel feedback pathway
@ast
Fyn and Lyn phosphorylate the ...... lates a novel feedback pathway
@en
Fyn and Lyn phosphorylate the ...... lates a novel feedback pathway
@nl
prefLabel
Fyn and Lyn phosphorylate the ...... lates a novel feedback pathway
@ast
Fyn and Lyn phosphorylate the ...... lates a novel feedback pathway
@en
Fyn and Lyn phosphorylate the ...... lates a novel feedback pathway
@nl
P2093
P1433
P1476
Fyn and Lyn phosphorylate the ...... lates a novel feedback pathway
@en
P2093
A. R. Dunn
C. A. Lowell
J. M. Pasquet
L. S. Quek
M. L. Hibbs
R. Cornall
S. P. Watson
P304
P407
P577
2000-12-15T00:00:00Z