The C-terminal domain of Rac1 contains two motifs that control targeting and signaling specificity.
about
Type I PIPK-alpha regulates directed cell migration by modulating Rac1 plasma membrane targeting and activationRac1-induced cell migration requires membrane recruitment of the nuclear oncogene SETCytoplasmic targeting of the proto-oncogene SET promotes cell spreading and migrationTargeting and activation of Rac1 are mediated by the exchange factor beta-Pix.14-3-3 proteins interact with a hybrid prenyl-phosphorylation motif to inhibit G proteinsSpatial regulation of CLASP affinity for microtubules by Rac1 and GSK3beta in migrating epithelial cellsThe Rac1 hypervariable region in targeting and signaling: a tail of many storiesRho GTPases, phosphoinositides, and actin: a tripartite framework for efficient vesicular traffickingInside-out regulation of ICAM-1 dynamics in TNF-alpha-activated endotheliumHow cells integrate complex stimuli: the effect of feedback from phosphoinositides and cell shape on cell polarization and motilityExtracting Diffusive States of Rho GTPase in Live Cells: Towards In Vivo BiochemistryIdentification of CrkL-SH3 binding proteins from embryonic murine brain: implications for Reelin signaling during brain development.Rac1 recruits the adapter protein CMS/CD2AP to cell-cell contacts.Isotype-specific degradation of Rac activated by the cytotoxic necrotizing factor 1.Suppression of Rac1 Signaling by Influenza A Virus NS1 Facilitates Viral ReplicationSingle-molecule tracking of small GTPase Rac1 uncovers spatial regulation of membrane translocation and mechanism for polarized signalingFilamin B mediates ICAM-1-driven leukocyte transendothelial migration.Pertussis toxin up-regulates angiotensin type 1 receptors through Toll-like receptor 4-mediated Rac activation.Nucleophosmin1 is a negative regulator of the small GTPase Rac1.Activation of Cdc42 is necessary for sustained oscillations of Ca2+ and PIP2 stimulated by antigen in RBL mast cells.Rac1 regulates the activity of mTORC1 and mTORC2 and controls cellular size.Modelling cell polarization driven by synthetic spatially graded Rac activationSUMOylation of the GTPase Rac1 is required for optimal cell migration.Liposome reconstitution and modulation of recombinant prenylated human Rac1 by GEFs, GDI1 and Pak1.Phosphoinositides and Rho proteins spatially regulate actin polymerization to initiate and maintain directed movement in a one-dimensional model of a motile cellNonpolarized signaling reveals two distinct modes of 3D cell migrationCross-talk between RhoH and Rac1 in regulation of actin cytoskeleton and chemotaxis of hematopoietic progenitor cellsSupervised membrane swimming: small G-protein lifeguards regulate PIPK signalling and monitor intracellular PtdIns(4,5)P2 pools.Glutaminase 2 is a novel negative regulator of small GTPase Rac1 and mediates p53 function in suppressing metastasis.Targeting and localized signalling by small GTPases.Phospholipase D signaling: orchestration by PIP2 and small GTPases.ROCK and Rho: biochemistry and neuronal functions of Rho-associated protein kinasesRas acylation, compartmentalization and signaling nanoclusters (Review).The role of small GTPases in neuronal morphogenesis and polarity.Breast cancer-associated gene 3 interacts with Rac1 and augments NF-κB signaling in vitro, but has no effect on RANKL-induced bone resorption in vivo.Rac1 acts in conjunction with Nedd4 and dishevelled-1 to promote maturation of cell-cell contacts.Elevated expression of RGS19 impairs the responsiveness of stress-activated protein kinases to serum.Rac2 Functions in Both Neutrophils and Macrophages To Mediate Motility and Host Defense in Larval Zebrafish.Activation of type I phosphatidylinositol 4-phosphate 5-kinase isoforms by the Rho GTPases, RhoA, Rac1, and Cdc42.A Rac1 inhibitory peptide suppresses antibody production and paw swelling in the murine collagen-induced arthritis model of rheumatoid arthritis
P2860
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P2860
The C-terminal domain of Rac1 contains two motifs that control targeting and signaling specificity.
description
2003 nî lūn-bûn
@nan
2003 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
The C-terminal domain of Rac1 ...... ing and signaling specificity.
@ast
The C-terminal domain of Rac1 ...... ing and signaling specificity.
@en
type
label
The C-terminal domain of Rac1 ...... ing and signaling specificity.
@ast
The C-terminal domain of Rac1 ...... ing and signaling specificity.
@en
prefLabel
The C-terminal domain of Rac1 ...... ing and signaling specificity.
@ast
The C-terminal domain of Rac1 ...... ing and signaling specificity.
@en
P2093
P2860
P356
P1476
The C-terminal domain of Rac1 ...... ing and signaling specificity.
@en
P2093
Eloise C Anthony
Jean Paul ten Klooster
Jon R Halstead
Paula B van Hennik
Peter L Hordijk
P2860
P304
39166-39175
P356
10.1074/JBC.M307001200
P407
P577
2003-07-21T00:00:00Z