Structural requirements for PAK activation by Rac GTPases - Wikidata - wikimedia - TriplyDB

Structural requirements for PAK activation by Rac GTPases

Structural requirements for PAK activation by Rac GTPases

http://www.wikidata.org/entity/Q28646548

about

Cdc42-induced activation of the mixed-lineage kinase SPRK in vivo. Requirement of the Cdc42/Rac interactive binding motif and changes in phosphorylation The small GTPase Rac3 interacts with the integrin-binding protein CIB and promotes integrin alpha(IIb)beta(3)-mediated adhesion and spreading A palmitoylation switch mechanism regulates Rac1 function and membrane organization.Cell-Penetrating Peptide as a Means of Directing the Differentiation of Induced-Pluripotent Stem Cells The Rac1 hypervariable region in targeting and signaling: a tail of many stories Cdc42: An essential Rho-type GTPase controlling eukaryotic cell polarity.The formin/diaphanous-related protein, FHOS, interacts with Rac1 and activates transcription from the serum response element P21 activated kinase-1 (Pak1) promotes prostate tumor growth and microinvasion via inhibition of transforming growth factor β expression and enhanced matrix metalloproteinase 9 secretion Phosphoinositides are essential coactivators for p21-activated kinase 1 Possible role of direct Rac1-Rab7 interaction in ruffled border formation of osteoclasts The C-terminal domain of Rac1 contains two motifs that control targeting and signaling specificity.Evidence that 12-lipoxygenase product 12-hydroxyeicosatetraenoic acid activates p21-activated kinase.Identification of phosphorylation sites in betaPIX and PAK1 Increased smooth muscle cell activation and neointima formation in response to injury in AIF-1 transgenic mice TGF-beta signaling-mediated morphogenesis: modulation of cell adhesion via cadherin endocytosis.RhoA and Rac1 GTPases play major and differential roles in stromal cell-derived factor-1-induced cell adhesion and chemotaxis in multiple myeloma.Macropinocytotic uptake and infection of human epithelial cells with species B2 adenovirus type 35.P21-activated kinase in inflammatory and cardiovascular disease.HER2/ErbB2-induced breast cancer cell migration and invasion require p120 catenin activation of Rac1 and Cdc42 Update on pulmonary edema: the role and regulation of endothelial barrier function.Signaling network prediction by the Ontology Fingerprint enhanced Bayesian network.Gq-mediated Akt translocation to the membrane: a novel PIP3-independent mechanism in platelets.Rapid global fitting of large fluorescence lifetime imaging microscopy datasets.PAK1 as a therapeutic target.PAK and other Rho-associated kinases--effectors with surprisingly diverse mechanisms of regulation A stretch of polybasic residues mediates Cdc42 GTPase-activating protein (CdGAP) binding to phosphatidylinositol 3,4,5-trisphosphate and regulates its GAP activity.A new computational approach to analyze human protein complexes and predict novel protein interactions.Targeting and localized signalling by small GTPases.Synergistic activation of p21-activated kinase 1 by phosphatidylinositol 4,5-bisphosphate and Rho GTPases p21-Activated kinase-1 and its role in integrated regulation of cardiac contractility.Roles of P21-activated kinases and associated proteins in epithelial wound healing.NADPH oxidase-dependent signaling in endothelial cells: role in physiology and pathophysiology Deconstructing signal transduction pathways that regulate the actin cytoskeleton in dendritic spines.Analysis of small GTPase signaling pathways using p21-activated kinase mutants that selectively couple to Cdc42.Rac2, a hematopoiesis-specific Rho GTPase, specifically regulates mast cell protease gene expression in bone marrow-derived mast cells.Exogenous miRNA-146a Enhances the Therapeutic Efficacy of Human Mesenchymal Stem Cells by Increasing Vascular Endothelial Growth Factor Secretion in the Ischemia/Reperfusion-Injured Heart.Modulation of myosin light-chain phosphorylation by p21-activated kinase 1 in Escherichia coli invasion of human brain microvascular endothelial cells.Vav and Rac activation in B cell antigen receptor endocytosis involves Vav recruitment to the adapter protein LAB.Rac2 Functions in Both Neutrophils and Macrophages To Mediate Motility and Host Defense in Larval Zebrafish.Spatially distinct binding of Cdc42 to PAK1 and N-WASP in breast carcinoma cells

P2860

Q22254031-4CACD18C-28EE-4673-91A5-7038D13DBBAA Q24292063-179FE4D4-DC4E-468B-B9D4-DF088B07B3A7 Q24299466-07EDD610-9C63-4F3F-B1BE-5F2E3B161649 Q26777415-8401E05F-5ADD-4657-B5AF-138E036ED966 Q26864271-43EAB286-7349-4036-B28F-DBAF5C9C7E48 Q27939243-F5D747FA-EB97-4D43-9DE1-223847FB8176 Q28190692-433BF3DA-7EB1-46AB-BE9E-62FEF3DFFDA4 Q28281866-5DAEB540-6216-4FB4-B315-7488BC0B46E1 Q28298123-53B0CCD6-111D-4D93-9B38-EE9BA5FC2CCF Q28584020-54B05C50-78A6-4C8B-BC6A-2D08DFB6BA6A Q30164617-3D4F2E05-9CF9-4626-B33A-BC810F235EDD Q30305816-D33D2734-662C-4C49-B19F-6E189CC805A8 Q30370259-68B1D06C-FC86-4E4E-87CE-1D17545DEC53 Q30439900-9FBD648E-1E7B-49B7-A22F-1179EE8A237F Q30443908-3D7F07B3-F192-4D7E-B9C1-F6BB26C3E641 Q30488936-AA5444C0-E14B-4BCF-AFB5-7D5150CF54FF Q30494333-6039AB28-D8D6-42DD-869B-E215B33FB40A Q34032604-8CE89BCC-376B-4B47-B1BE-0A78FF8AA533 Q34121631-5CB7C957-4DBC-445A-9659-608552E2879F Q34381569-AEFBE9C1-B12F-4DA0-B228-B3DA41C54156 Q34530613-886D92CD-3CC7-4E73-82ED-98F2F1E38B52 Q34802394-74A80187-544B-4A9E-8FC2-A759AAED259E Q34935763-3F635828-EE48-43C0-9A47-DD90CD50E57C Q35108164-3918756A-AD9D-4FC8-B4BF-080B4ED4B489 Q35952627-7C188200-846A-49D7-A926-88DAB6448214 Q36003886-67389D54-46A5-4C45-9AB6-6CD46586BEF4 Q36465531-09629349-D944-48C5-A505-A15241BEE710 Q36677555-C9462E6C-A84B-470F-BCD7-4C4375D7BF78 Q36724918-7B0C4ACB-D901-4CC2-9D4A-9F793B944C76 Q36869603-1F82982E-46D6-4F16-B7C0-B202A5C9258C Q37188103-216CDCD0-3801-46A1-A392-890E5C835659 Q37265507-C4E3624C-C75C-42C4-82BD-D4582C76B3A3 Q37981628-08E0CAE4-80BC-4A03-806C-D4CCD60260E0 Q38297631-19C7C43F-0044-47FE-8F42-486B7F677389 Q38362182-0A39C1AE-7DE7-4D4B-952F-1254A9623726 Q38837993-D4029738-94EE-4248-9FD1-0FBC529D6688 Q39746225-4EDAB2D9-296D-426F-BBE6-85E40341989B Q39783210-8775AD57-7669-45BF-A744-CF1CCF94F79D Q40455048-E2830730-DFD7-45B1-8759-69A7CFD910B8 Q40457910-2E8ABF03-1218-41DC-92AA-F2C13D12A89A

P2860

Structural requirements for PAK activation by Rac GTPases

http://www.wikidata.org/entity/Q28646548

description

1998 թուականի Օգոստոսին հրատարակուած գիտական յօդուած

@hyw

1998 թվականի օգոստոսին հրատարակված գիտական հոդված

@hy

article publié dans la revue scientifique Journal of Biological Chemistry

@fr

artículu científicu espublizáu en 1998

@ast

im August 1998 veröffentlichter wissenschaftlicher Artikel

@de

scientific journal article

@en

vedecký článok (publikovaný 1998/08/21)

@sk

vědecký článek publikovaný v roce 1998

@cs

wetenschappelijk artikel (gepubliceerd op 1998/08/21)

@nl

наукова стаття, опублікована в серпні 1998

@uk

name

Structural requirements for PAK activation by Rac GTPases

@ast

Structural requirements for PAK activation by Rac GTPases

@en

Structural requirements for PAK activation by Rac GTPases

@nl

type

label

Structural requirements for PAK activation by Rac GTPases

@ast

Structural requirements for PAK activation by Rac GTPases

@en

Structural requirements for PAK activation by Rac GTPases

@nl

prefLabel

Structural requirements for PAK activation by Rac GTPases

@ast

Structural requirements for PAK activation by Rac GTPases

@en

Structural requirements for PAK activation by Rac GTPases

@nl

P1433

Q28646548-F2B8DCCA-EDFD-4849-BCD3-54966E41FFC4

P1476

Q28646548-0B56E888-FF59-4D76-BD81-A92B4DA10C5B

P2093

Q28646548-72169722-7B19-464F-903A-D71D54F4AB92

Q28646548-89D1A94B-1FC5-484A-9BC3-8CD9DA23E44C

Q28646548-B8A3EB1C-3BB3-4F5D-8C6B-44E76670B3E8

Q28646548-B9F5432B-EA43-4149-BAEC-692CA584E525

Q28646548-F5A6E1EE-2102-47D3-9C26-770481F14A97

P2860

Q28646548-08B536BA-5A36-496E-959B-02E001FF521C

Q28646548-13C19235-6D1D-476E-A3C5-DB964720C79B

Q28646548-1CCA4747-F7F3-4805-9EE9-43F147A1AB09

Q28646548-20F83371-C340-43D6-A94C-3B6DD397434F

Q28646548-2E03522D-ABD8-45F0-97E0-C0A29685A7D5

Q28646548-34AB353A-F670-442E-8570-F1956D1F2105

Q28646548-37615F83-F466-4903-9E08-084D326E7B43

Q28646548-3AF89FF6-FF2E-4CAD-AA01-88DA93898D27

Q28646548-42B9AE62-E200-4E7F-8C37-C2271F170AD1

Q28646548-4451C5AF-F97D-4518-BEE6-CD86AB9C1410

P304

Q28646548-9338DF75-51EA-44BF-A832-6C6C99B4143E

P31

Q28646548-99C965C7-95FB-4ADE-8861-9BEF2A8F1553

P356

Q28646548-693491A8-DB8E-451D-B54D-04351047ADBF

P407

Q28646548-42AEE3A9-0F77-4538-AA06-8312124B20F8

P433

Q28646548-ACAE1857-2BF5-4316-B09A-28A00F31D86F

P478

Q28646548-035BFDF5-80F3-4F93-8636-75F5492CD78E

P577

Q28646548-D444D886-D685-49DF-982A-96163713F236

P698

Q28646548-CA59C17B-00A4-4FC2-9B47-D9266EEDCD24

P356

JBC.273.34.21512

P1433

Journal of Biological Chemistry

P1476

Structural requirements for PAK activation by Rac GTPases

@en

P2093

A. M. Reilly

http://www.w3.org/2001/XMLSchema#string

D. Warnock

http://www.w3.org/2001/XMLSchema#string

J. H. Jackson

http://www.w3.org/2001/XMLSchema#string

U. G. Knaus

http://www.w3.org/2001/XMLSchema#string

Y. Wang

http://www.w3.org/2001/XMLSchema#string

P2860

A conserved binding motif defines numerous candidate target proteins for both Cdc42 and Rac GTPases

Wiskott-Aldrich syndrome protein, a novel effector for the GTPase CDC42Hs, is implicated in actin polymerization

Human p21-activated kinase (Pak1) regulates actin organization in mammalian cells

PAK kinases are directly coupled to the PIX family of nucleotide exchange factors

A non-receptor tyrosine kinase that inhibits the GTPase activity of p21cdc42

The GTPase-activating protein n-chimaerin cooperates with Rac1 and Cdc42Hs to induce the formation of lamellipodia and filopodia

The small GTP-binding protein rho regulates the assembly of focal adhesions and actin stress fibers in response to growth factors

The small GTP-binding protein rac regulates growth factor-induced membrane ruffling

Rho, rac, and cdc42 GTPases regulate the assembly of multimolecular focal complexes associated with actin stress fibers, lamellipodia, and filopodia

A brain serine/threonine protein kinase activated by Cdc42 and Rac1

P304

21512–21518

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1074/JBC.273.34.21512

http://www.w3.org/2001/XMLSchema#string

P407

P433

34

http://www.w3.org/2001/XMLSchema#string

P478

273

http://www.w3.org/2001/XMLSchema#string

P577

1998-08-21T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P698

9705280

http://www.w3.org/2001/XMLSchema#string