Rac1 regulates the activity of mTORC1 and mTORC2 and controls cellular size. - Wikidata - wikimedia - TriplyDB

Rac1 regulates the activity of mTORC1 and mTORC2 and controls cellular size.

Rac1 regulates the activity of mTORC1 and mTORC2 and controls cellular size.

http://www.wikidata.org/entity/Q34176565

about

Regulation of TOR by small GTPases Inhibition of the Mechanistic Target of Rapamycin (mTOR)-Rapamycin and Beyond Regulation of the Target of Rapamycin and Other Phosphatidylinositol 3-Kinase-Related Kinases by Membrane Targeting The Rac1 hypervariable region in targeting and signaling: a tail of many stories Multifaceted role of insulin-like growth factors and mammalian target of rapamycin in skeletal muscle Growth factor signaling to mTORC1 by amino acid-laden macropinosomes.The exomer cargo adaptor structure reveals a novel GTPase-binding domain Quantitative Analysis of Prenylated RhoA Interaction with Its Chaperone, RhoGDI Cancer Cell Fusion: Mechanisms Slowly Unravel A genome-wide siRNA screen in mammalian cells for regulators of S6 phosphorylation The Mechanistic Target of Rapamycin: The Grand ConducTOR of Metabolism and Aging Antioxidant Treatment and Induction of Autophagy Cooperate to Reduce Desmin Aggregation in a Cellular Model of Desminopathy The Complex Roles of Mechanistic Target of Rapamycin in Adipocytes and Beyond.mTOR and neuronal cell cycle reentry: How impaired brain insulin signaling promotes Alzheimer's disease.Prevention of alveolar destruction and airspace enlargement in a mouse model of pulmonary lymphangioleiomyomatosis (LAM)Mammalian target of rapamycin and Rictor control neutrophil chemotaxis by regulating Rac/Cdc42 activity and the actin cytoskeleton Therapeutic sensitivity to Rac GTPase inhibition requires consequential suppression of mTORC1, AKT, and MEK signaling in breast cancer Quality and freshness of human bone marrow-derived mesenchymal stem cells decrease over time after trypsinization and storage in phosphate-buffered saline Identification of mTORC2 as a necessary component of HRG/ErbB2-dependent cellular transformation Auxin Signaling in Regulation of Plant Translation Reinitiation IKBKE protein activates Akt independent of phosphatidylinositol 3-kinase/PDK1/mTORC2 and the pleckstrin homology domain to sustain malignant transformation The evolution of the TOR pathway and its role in cancer.The Rac Inhibitor EHop-016 Inhibits Mammary Tumor Growth and Metastasis in a Nude Mouse Model.Lysosomal mTORC2/PHLPP1/Akt Regulate Chaperone-Mediated Autophagy Genomic loss of tumor suppressor miRNA-204 promotes cancer cell migration and invasion by activating AKT/mTOR/Rac1 signaling and actin reorganization Growing knowledge of the mTOR signaling network.The mTOR signaling pathway as a treatment target for intracranial neoplasms Intersection of mTOR and STAT signaling in immunity Regulation of mTOR activity in Snell dwarf and GH receptor gene-disrupted mice.Mammalian target of rapamycin complex 2 (mTORC2) is a critical determinant of bladder cancer invasion Gab1 is essential for membrane translocation, activity and integrity of mTORCs after EGF stimulation in urothelial cell carcinoma.Liposome reconstitution and modulation of recombinant prenylated human Rac1 by GEFs, GDI1 and Pak1.mTORC2 is required for rit-mediated oxidative stress resistance.Review series: TOR kinase complexes and cell migration.Elevated PI3K signaling drives multiple breast cancer subtypes.Crucial roles of TNFAIP8 protein in regulating apoptosis and Listeria infection.SPARC Controls Melanoma Cell Plasticity through Rac1.Lipin-1 regulates cancer cell phenotype and is a potential target to potentiate rapamycin treatment Deconvoluting mTOR biology mTOR complex 2 signaling and functions

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P2860

Rac1 regulates the activity of mTORC1 and mTORC2 and controls cellular size.

http://www.wikidata.org/entity/Q34176565

description

2011 nî lūn-bûn

@nan

2011 թուականի Ապրիլին հրատարակուած գիտական յօդուած

@hyw

2011 թվականի ապրիլին հրատարակված գիտական հոդված

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2011年の論文

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2011年論文

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2011年論文

@zh-hant

2011年論文

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2011年論文

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2011年論文

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2011年论文

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name

Rac1 regulates the activity of mTORC1 and mTORC2 and controls cellular size.

@ast

Rac1 regulates the activity of mTORC1 and mTORC2 and controls cellular size.

@en

Rac1 regulates the activity of mTORC1 and mTORC2 and controls cellular size.

@nl

type

label

Rac1 regulates the activity of mTORC1 and mTORC2 and controls cellular size.

@ast

Rac1 regulates the activity of mTORC1 and mTORC2 and controls cellular size.

@en

Rac1 regulates the activity of mTORC1 and mTORC2 and controls cellular size.

@nl

prefLabel

Rac1 regulates the activity of mTORC1 and mTORC2 and controls cellular size.

@ast

Rac1 regulates the activity of mTORC1 and mTORC2 and controls cellular size.

@en

Rac1 regulates the activity of mTORC1 and mTORC2 and controls cellular size.

@nl

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J.MOLCEL.2011.03.017

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Rac1 regulates the activity of mTORC1 and mTORC2 and controls cellular size.

@en

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Abdelhafid Saci

http://www.w3.org/2001/XMLSchema#string

Christopher L Carpenter

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P2860

P-Rex1, a PtdIns(3,4,5)P3- and Gbetagamma-regulated guanine-nucleotide exchange factor for Rac

Phosphorylation and regulation of Akt/PKB by the rictor-mTOR complex

Mammalian TOR complex 2 controls the actin cytoskeleton and is rapamycin insensitive

P-Rex1 links mammalian target of rapamycin signaling to Rac activation and cell migration

The Rag GTPases bind raptor and mediate amino acid signaling to mTORC1

mTOR complex 2 (mTORC2) controls hydrophobic motif phosphorylation and activation of serum- and glucocorticoid-induced protein kinase 1 (SGK1)

Biochemical and functional characterizations of small GTPase Rheb and TSC2 GAP activity

Mammalian target of rapamycin (mTOR): conducting the cellular signaling symphony

The PRK2 kinase is a potential effector target of both Rho and Rac GTPases and regulates actin cytoskeletal organization

The selectivity of protein kinase inhibitors: a further update

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10.1016/J.MOLCEL.2011.03.017

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1

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Lewis C. Cantley

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2011-04-01T00:00:00Z

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51033357

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