Uncovering novel reproductive defects in neurokinin B receptor null mice: closing the gap between mice and men.
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Estradiol Membrane-Initiated Signaling and Female ReproductionInteractions between kisspeptins and neurokinin BLeptin receptor null mice with reexpression of LepR in GnRHR expressing cells display elevated FSH levels but remain in a prepubertal stateNELF knockout is associated with impaired pubertal development and subfertility.Neurokinin B is critical for normal timing of sexual maturation but dispensable for adult reproductive function in female miceArcuate kisspeptin/neurokinin B/dynorphin (KNDy) neurons mediate the estrogen suppression of gonadotropin secretion and body weight.Neurokinin-3 receptor activation in the retrochiasmatic area is essential for the full pre-ovulatory luteinising hormone surge in ewes.The integrated hypothalamic tachykinin-kisspeptin system as a central coordinator for reproductionEffects and interactions of tachykinins and dynorphin on FSH and LH secretion in developing and adult ratsSubstance p regulates puberty onset and fertility in the female mouse.Augmentation of Metastin/Kisspeptin mRNA Expression by the Proestrous Luteinizing Hormone Surge in Granulosa Cells of Rats: Implications for Luteinization.Tacking toward reconciliation on Tacr3/TACR3 mutations.Testing the Critical Window Hypothesis of Timing and Duration of Estradiol Treatment on Hypothalamic Gene Networks in Reproductively Mature and Aging Female RatsNew insights into the control of pulsatile GnRH release: the role of Kiss1/neurokinin B neurons.Targeted Mutagenesis of the Hypophysiotropic Gnrh3 in Zebrafish (Danio rerio) Reveals No Effects on Reproductive PerformanceHyperprolactinemia-induced ovarian acyclicity is reversed by kisspeptin administration.Neurokinin B and the control of the gonadotropic axis in the rat: developmental changes, sexual dimorphism, and regulation by gonadal steroids.Increased neurokinin B (Tac2) expression in the mouse arcuate nucleus is an early marker of pubertal onset with differential sensitivity to sex steroid-negative feedback than Kiss1.Low degree of overlap between kisspeptin, neurokinin B, and dynorphin immunoreactivities in the infundibular nucleus of young male human subjects challenges the KNDy neuron concept.Neurokinin B causes acute GnRH secretion and repression of GnRH transcription in GT1-7 GnRH neuronsNeurokinin3 receptor as a target to predict and improve learning and memory in the aged organism.Use of genetic models of idiopathic hypogonadotrophic hypogonadism in mice and men to understand the mechanisms of diseaseKisspeptin and clinical disorders.A system biology approach to identify regulatory pathways underlying the neuroendocrine control of female puberty in rats and nonhuman primatesTACR3 mutations disrupt NK3R function through distinct mechanisms in GnRH-deficient patients.A role for neurokinin B in pulsatile GnRH secretion in the ewe.Current and future applications of GnRH, kisspeptin and neurokinin B analogues.Control of puberty onset and fertility by gonadotropin-releasing hormone neurons.Do Substance P and Neurokinin A Play Important Roles in the Control of LH Secretion in Ewes?Expression of Tachykinins and Tachykinin Receptors and Interaction with Kisspeptin in Human Granulosa and Cumulus Cells.Analysis of the Expression of Tachykinins and Tachykinin Receptors in the Rat Uterus During Early Pregnancy.KLB, encoding β-Klotho, is mutated in patients with congenital hypogonadotropic hypogonadism.Purification and Transcriptomic Analysis of Mouse Fetal Leydig Cells Reveals Candidate Genes for Specification of Gonadal Steroidogenic Cells.Expression of neurokinin B/NK3 receptor and kisspeptin/KISS1 receptor in human granulosa cells.Reproductive physiology of a humanized GnRH receptor mouse model: application in evaluation of human-specific analogs.Photoperiodic co-regulation of kisseptin, neurokinin B and dynorphin in the hypothalamus of a seasonal rodent.Three-dimensional imaging of KNDy neurons in the mammalian brain using optical tissue clearing and multiple-label immunocytochemistry.Neurokinin B receptor antagonism decreases luteinising hormone pulse frequency and amplitude and delays puberty onset in the female rat.Tachykinin-3 Genes and Peptides Characterized in a Basal Teleost, the European Eel: Evolutionary Perspective and Pituitary Role.Genes underlying delayed puberty
P2860
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P2860
Uncovering novel reproductive defects in neurokinin B receptor null mice: closing the gap between mice and men.
description
2012 nî lūn-bûn
@nan
2012 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
name
Uncovering novel reproductive ...... the gap between mice and men.
@ast
Uncovering novel reproductive ...... the gap between mice and men.
@en
type
label
Uncovering novel reproductive ...... the gap between mice and men.
@ast
Uncovering novel reproductive ...... the gap between mice and men.
@en
prefLabel
Uncovering novel reproductive ...... the gap between mice and men.
@ast
Uncovering novel reproductive ...... the gap between mice and men.
@en
P2093
P2860
P356
P1433
P1476
Uncovering novel reproductive ...... the gap between mice and men.
@en
P2093
Claudia S Caligioni
Jasmine J Yang
Stephanie B Seminara
Yee-Ming Chan
P2860
P304
P356
10.1210/EN.2011-1949
P407
P577
2012-01-17T00:00:00Z