Anti-HIV agents that selectively target retroviral nucleocapsid protein zinc fingers without affecting cellular zinc finger proteins.
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Redox-directed cancer therapeutics: molecular mechanisms and opportunitiesCysteine-modifying agents: a possible approach for effective anticancer and antiviral drugsCoronavirus N Protein N-Terminal Domain (NTD) Specifically Binds the Transcriptional Regulatory Sequence (TRS) and Melts TRS-cTRS RNA DuplexesMultiple effects of an anti-human immunodeficiency virus nucleocapsid inhibitor on virus morphology and replication.Targeting of arenavirus RNA synthesis by a carboxamide-derivatized aromatic disulfide with virucidal activityMinireview: Not picking pockets: nuclear receptor alternate-site modulators (NRAMs)Human immunodeficiency virus and AIDS: insights from animal lentivirusesInactivation of HIV-1 nucleocapsid protein P7 by pyridinioalkanoyl thioesters. Characterization of reaction products and proposed mechanism of action.Novel compounds in preclinical/early clinical development for the treatment of HIV infections.Anisotropic, Polarizable Molecular Mechanics Studies of Inter- and Intramolecular Interactions and Ligand-Macromolecule Complexes. A Bottom-Up Strategy.Advances in targeting nucleocapsid-nucleic acid interactions in HIV-1 therapy.New anti-HIV agents and targets.Single DNA molecule stretching measures the activity of chemicals that target the HIV-1 nucleocapsid protein.The interaction between HIV-1 Tat and human cyclin T1 requires zinc and a critical cysteine residue that is not conserved in the murine CycT1 proteinDevelopment of a cell-based assay probing the specific interaction between the human immunodeficiency virus type 1 nucleocapsid and psi RNA in vivo.Molecular mechanism of the Zn2+-induced folding of the distal CCHC finger motif of the HIV-1 nucleocapsid proteinBeyond plasma membrane targeting: role of the MA domain of Gag in retroviral genome encapsidation.The next generation of HIV/AIDS drugs: novel and developmental antiHIV drugs and targets.Enhancement of the physicochemical properties of [Pt(dien)(nucleobase)]2+ for HIVNCp7 targeting.Arenavirus Z protein as an antiviral target: virus inactivation and protein oligomerization by zinc finger-reactive compounds.HIV-1 inactivation by 4-vinylpyridine is enhanced by dissociating Zn(2+) from nucleocapsid protein.Potential inhibition of HIV-1 encapsidation by oligoribonucleotide-dendrimer nanoparticle complexes.Zinc finger proteins as templates for metal ion exchange and ligand reactivity. Chemical and biological consequences.Structure of the zinc finger domain encompassing residues 13-51 of the nucleocapsid protein from simian immunodeficiency virus.Some nontoxic metal-based drugs for selected prevalent tropical pathogenic diseases.Zinc Finger-Containing Cellular Transcription Corepressor ZBTB25 Promotes Influenza Virus RNA Transcription and Is a Target for Zinc Ejector Drugs.Reactive cysteine in the structural Zn(2+) site of the C1B domain from PKCα.Antiviral and virucidal activities against arenaviruses of zinc-finger active compounds.Cysteine 155 plays an important role in the assembly of Mycobacterium tuberculosis FtsZ.Cys(x)His(y)-Zn2+ interactions: thiol vs. thiolate coordination.On the design of zinc-finger models with cyclic peptides bearing a linear tail.Tuning the reactivity of Sp1 zinc fingers with platinum complexes.Mapping the binding site of colchicinoids on beta -tubulin. 2-Chloroacetyl-2-demethylthiocolchicine covalently reacts predominantly with cysteine 239 and secondarily with cysteine 354.Agents that target cysteine residues of biomolecules and their therapeutic potential
P2860
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P2860
Anti-HIV agents that selectively target retroviral nucleocapsid protein zinc fingers without affecting cellular zinc finger proteins.
description
1998 nî lūn-bûn
@nan
1998 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
1998 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
name
Anti-HIV agents that selective ...... cellular zinc finger proteins.
@ast
Anti-HIV agents that selective ...... cellular zinc finger proteins.
@en
type
label
Anti-HIV agents that selective ...... cellular zinc finger proteins.
@ast
Anti-HIV agents that selective ...... cellular zinc finger proteins.
@en
prefLabel
Anti-HIV agents that selective ...... cellular zinc finger proteins.
@ast
Anti-HIV agents that selective ...... cellular zinc finger proteins.
@en
P2093
P356
P1476
Anti-HIV agents that selective ...... cellular zinc finger proteins.
@en
P2093
P304
P356
10.1021/JM9708543
P407
P577
1998-04-01T00:00:00Z