Macrophage cytotoxicity produced by adenylate cyclase toxin from Bordetella pertussis: more than just making cyclic AMP!
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Bordetella adenylate cyclase toxin mobilizes its beta2 integrin receptor into lipid rafts to accomplish translocation across target cell membrane in two stepsPertussis toxin and adenylate cyclase toxin: key virulence factors of Bordetella pertussis and cell biology toolsRTX proteins: a highly diverse family secreted by a common mechanismClostridium difficile Toxin B causes epithelial cell necrosis through an autoprocessing-independent mechanismCalcium influx rescues adenylate cyclase-hemolysin from rapid cell membrane removal and enables phagocyte permeabilization by toxin pores.Erythrocyte lysis and Xenopus laevis oocyte rupture by recombinant Plasmodium falciparum hemolysin IIIPertussis: Microbiology, Disease, Treatment, and Prevention.Albumin, in the Presence of Calcium, Elicits a Massive Increase in Extracellular Bordetella Adenylate Cyclase Toxin.Bordetella adenylate cyclase toxin interacts with filamentous haemagglutinin to inhibit biofilm formation in vitro.Use of a Toxin Neutralization Assay To Characterize the Serologic Response to Adenylate Cyclase Toxin after Infection with Bordetella pertussisCyclic AMP-mediated suppression of neutrophil extracellular trap formation and apoptosis by the Bordetella pertussis adenylate cyclase toxin.Cell cycle arrest induced by the bacterial adenylate cyclase toxins from Bacillus anthracis and Bordetella pertussis.Differences in purinergic amplification of osmotic cell lysis by the pore-forming RTX toxins Bordetella pertussis CyaA and Actinobacillus pleuropneumoniae ApxIA: the role of pore size.Delivery of large heterologous polypeptides across the cytoplasmic membrane of antigen-presenting cells by the Bordetella RTX hemolysin moiety lacking the adenylyl cyclase domain.Role of CD11b/CD18 in the process of intoxication by the adenylate cyclase toxin of Bordetella pertussisSelective translocation of the Bordetella pertussis adenylate cyclase toxin across the basolateral membranes of polarized epithelial cellsThe adenylate cyclase toxins of Bacillus anthracis and Bordetella pertussis promote Th2 cell development by shaping T cell antigen receptor signaling.Cross-species protection mediated by a Bordetella bronchiseptica strain lacking antigenic homologs present in acellular pertussis vaccines.Identification of a CO2 responsive regulon in Bordetella.Calpain-Mediated Processing of Adenylate Cyclase Toxin Generates a Cytosolic Soluble Catalytically Active N-Terminal Domain.Ca2+ influx and tyrosine kinases trigger Bordetella adenylate cyclase toxin (ACT) endocytosis. Cell physiology and expression of the CD11b/CD18 integrin major determinants of the entry route.The Bordetella pertussis adenylate cyclase toxin binds to T cells via LFA-1 and induces its disengagement from the immune synapseCalcium, acylation, and molecular confinement favor folding of Bordetella pertussis adenylate cyclase CyaA toxin into a monomeric and cytotoxic formModulation of the host interferon response and ISGylation pathway by B. pertussis filamentous hemagglutininReplacement of adenylate cyclase toxin in a lineage of Bordetella bronchisepticaActive and passive immunizations with Bordetella colonization factor A protect mice against respiratory challenge with Bordetella bronchisepticaVirulence factor secretion and translocation by Bordetella species.Otopathogenic Pseudomonas aeruginosa Enters and Survives Inside MacrophagesSpecific humoral immune response induced by propionibacterium acnes can prevent Actinobacillus pleuropneumoniae infection in miceThe virulence factors of Bordetella pertussis: talented modulators of host immune response.Bordetella adenylate cyclase toxin: a unique combination of a pore-forming moiety with a cell-invading adenylate cyclase enzyme.Phospholipase A activity of adenylate cyclase toxin mediates translocation of its adenylate cyclase domain.Transmembrane segments of complement receptor 3 do not participate in cytotoxic activities but determine receptor structure required for action of Bordetella adenylate cyclase toxin.Bordetella adenylate cyclase toxin promotes calcium entry into both CD11b+ and CD11b- cells through cAMP-dependent L-type-like calcium channels.Cyclic AMP-Elevating Capacity of Adenylate Cyclase Toxin-Hemolysin Is Sufficient for Lung Infection but Not for Full Virulence of Bordetella pertussis.Pore-forming and enzymatic activities of Bordetella pertussis adenylate cyclase toxin synergize in promoting lysis of monocytes.Negatively charged residues of the segment linking the enzyme and cytolysin moieties restrict the membrane-permeabilizing capacity of adenylate cyclase toxin.The conserved tyrosine residue 940 plays a key structural role in membrane interaction of Bordetella adenylate cyclase toxin.Allosteric activation of Bordetella pertussis adenylyl cyclase by calmodulin: molecular dynamics and mutagenesis studiesCytidylyl and uridylyl cyclase activity of bacillus anthracis edema factor and Bordetella pertussis CyaA.
P2860
Q21131558-00047133-C456-4873-81CA-476E2F5B0CCBQ24602050-FBDA04A0-741E-4954-AE75-A15788C1757FQ24630254-8CA84027-C6C4-41BE-8915-7DF0A612472AQ27339318-E1A3EF22-A9CD-4EB9-A573-8E015853E1C6Q27346834-6FB55B4A-D13F-4E3C-95CE-735C02A3486CQ27974478-32FA4590-67B9-4EC7-BB55-467B56088BDFQ30251684-2C54B3B3-42E2-4AB5-B74E-0D932EF37D02Q30252682-38E39517-2DD1-4899-AC91-D13042949E27Q30275500-8AF4544B-CCD2-470B-97E5-F850227C7119Q30275563-5EB8E99D-7B59-48B1-8660-FDA809F39FC0Q30303150-263E0152-4C66-42F6-9D29-177FEF4EF987Q30411214-6492E28F-BDF8-44F3-84DC-A09BE798078AQ30412779-C2234A9B-C82B-4FA4-9B37-B0F0D51EFE7CQ30425161-DD91B999-EC98-42DA-BE08-A80881CF6142Q30425735-00F1312A-B204-4516-8946-9B9648D3BA65Q30432788-D5B7F114-3A4D-49B3-96A2-B9252F7C4F4BQ33415455-A7C52808-6D47-4356-AF41-6A4DBDD001D4Q33825964-A8EAB24D-E900-476F-AB5E-6B141EDDE1A5Q34462226-C0CB1CE7-C2C5-46E0-B4ED-6A5EE94976E2Q34807865-09899FC3-5506-427F-8891-47F7EF70138DQ34994573-34A0EBCE-DDCD-46C2-91EF-635F1ED85916Q35213542-C67D05DF-F995-4DCA-836E-2CD9AB74F5A4Q35260287-AB6A342E-49CF-4B4D-ADF5-DFB63CDD3325Q35582662-1D52A590-AC62-4800-B99A-B7A681D3EFE1Q36804424-6FC0B090-0DE6-44E7-BC0B-C8600FCA41C4Q37075478-79D2E18C-A820-4700-A7EB-1950C99C94AAQ37382931-AE58A285-3D73-4904-8F8F-20ED51A42E29Q37421175-BBCC1F22-D58D-4FCF-9E8C-FDF9CAB66A97Q37643330-494CCDAD-4301-4DC6-AE88-B8311DB32EF4Q38129761-93F73FE1-3692-46A9-B07F-7C45B6B706BCQ38590644-26A90512-D597-43B9-941F-97092BCE8A48Q38650797-D4DDB3A0-6A82-4D72-80B2-95A889BFD677Q38800261-17D05C59-A45F-42E2-A5AF-F4126299E179Q39781846-E4E4602F-8688-40BE-873E-9C83872E10CBQ40257250-E31AF6BB-FDA3-411D-81C8-68610B35F7F7Q40301344-4C202220-97F3-401D-B0B9-4DBAFEB00355Q40991060-5B9F491F-565B-4DAE-8CB1-79D94C37FE53Q41518063-1ED068BB-A953-4BA6-B8B7-8F15FC3F14E5Q41891782-334710F9-0DF9-4B3B-B184-62A62C89B2E5Q41965798-AAF8E472-977A-4463-98B4-4EE3FE78504F
P2860
Macrophage cytotoxicity produced by adenylate cyclase toxin from Bordetella pertussis: more than just making cyclic AMP!
description
2006 nî lūn-bûn
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2006 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2006年の論文
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2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
Macrophage cytotoxicity produc ...... e than just making cyclic AMP!
@ast
Macrophage cytotoxicity produc ...... e than just making cyclic AMP!
@en
type
label
Macrophage cytotoxicity produc ...... e than just making cyclic AMP!
@ast
Macrophage cytotoxicity produc ...... e than just making cyclic AMP!
@en
prefLabel
Macrophage cytotoxicity produc ...... e than just making cyclic AMP!
@ast
Macrophage cytotoxicity produc ...... e than just making cyclic AMP!
@en
P2093
P2860
P921
P1476
Macrophage cytotoxicity produc ...... e than just making cyclic AMP!
@en
P2093
Erik L Hewlett
Gina M Donato
Mary C Gray
P2860
P304
P356
10.1111/J.1365-2958.2005.04958.X
P407
P577
2006-01-01T00:00:00Z