Cytidylyl and uridylyl cyclase activity of bacillus anthracis edema factor and Bordetella pertussis CyaA.
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Analysis of substrate specificity and kinetics of cyclic nucleotide phosphodiesterases with N'-methylanthraniloyl-substituted purine and pyrimidine 3',5'-cyclic nucleotides by fluorescence spectrometryCross Kingdom Activators of Five Classes of Bacterial EffectorsBacillus anthracis edema factor substrate specificity: evidence for new modes of actionBinding of regulatory subunits of cyclic AMP-dependent protein kinase to cyclic CMP agarosePseudomonas aeruginosa exotoxin Y is a promiscuous cyclase that increases endothelial tau phosphorylation and permeabilityMolecular motions as a drug target: mechanistic simulations of anthrax toxin edema factor function led to the discovery of novel allosteric inhibitors.The Pseudomonas aeruginosa exoenzyme Y impairs endothelial cell proliferation and vascular repair following lung injury.Empirical valence bond simulations of the chemical mechanism of ATP to cAMP conversion by anthrax edema factor.Nitric oxide/cGMP pathway signaling actively down-regulates α4β1-integrin affinity: an unexpected mechanism for inducing cell de-adhesion.Bis-halogen-anthraniloyl-substituted nucleoside 5'-triphosphates as potent and selective inhibitors of Bordetella pertussis adenylyl cyclase toxin.Nucleotidyl cyclase activity of particulate guanylyl cyclase A: comparison with particulate guanylyl cyclases E and F, soluble guanylyl cyclase and bacterial adenylyl cyclases CyaA and edema factorPseudomonas aeruginosa exotoxin Y-mediated tau hyperphosphorylation impairs microtubule assembly in pulmonary microvascular endothelial cells.B. anthracis associated cardiovascular dysfunction and shock: the potential contribution of both non-toxin and toxin componentsInteraction of cCMP with the cGK, cAK and MAPK Kinases in Murine Tissues.Raxibacumab augments hemodynamic support and improves outcomes during shock with B. anthracis edema toxin alone or together with lethal toxin in canines.Heterogeneity of pulmonary endothelial cyclic nucleotide response to Pseudomonas aeruginosa ExoY infection.Lipopolysaccharide-induced pulmonary endothelial barrier disruption and lung edema: critical role for bicarbonate stimulation of AC10B. anthracis edema toxin increases cAMP levels and inhibits phenylephrine-stimulated contraction in a rat aortic ring modelcGMP becomes a drug target.Identification of cCMP and cUMP Substrate Proteins and Cross Talk Between cNMPs.cUMP hydrolysis by PDE3A.Holistic Methods for the Analysis of cNMP Effects.PDE7A1 hydrolyzes cCMP.Structure-activity relationships for the interactions of 2'- and 3'-(O)-(N-methyl)anthraniloyl-substituted purine and pyrimidine nucleotides with mammalian adenylyl cyclases.Inhibition of the adenylyl cyclase toxin, edema factor, from Bacillus anthracis by a series of 18 mono- and bis-(M)ANT-substituted nucleoside 5'-triphosphates.The Pseudomonas aeruginosa Exoenzyme Y: A Promiscuous Nucleotidyl Cyclase Edema Factor and Virulence Determinant.Actin activates Pseudomonas aeruginosa ExoY nucleotidyl cyclase toxin and ExoY-like effector domains from MARTX toxins.Structure-Function Relationships Underlying the Capacity of Bordetella Adenylate Cyclase Toxin to Disarm Host Phagocytes.Cyclic CMP and cyclic UMP: new (old) second messengers.Site I Inactivation Impacts Calmodulin Calcium Binding and Activation of Bordetella pertussis Adenylate Cyclase Toxin.cCMP and cUMP Across the Tree of Life: From cCMP and cUMP Generators to cCMP- and cUMP-Regulated Cell Functions.3',5'-cIMP as Potential Second Messenger in the Vascular Wall.Differential regulation of actin-activated nucleotidyl cyclase virulence factors by filamentous and globular actin
P2860
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P2860
Cytidylyl and uridylyl cyclase activity of bacillus anthracis edema factor and Bordetella pertussis CyaA.
description
2010 nî lūn-bûn
@nan
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
2010年论文
@zh
2010年论文
@zh-cn
name
Cytidylyl and uridylyl cyclase ...... and Bordetella pertussis CyaA.
@en
type
label
Cytidylyl and uridylyl cyclase ...... and Bordetella pertussis CyaA.
@en
prefLabel
Cytidylyl and uridylyl cyclase ...... and Bordetella pertussis CyaA.
@en
P2093
P2860
P356
P1433
P1476
Cytidylyl and uridylyl cyclase ...... and Bordetella pertussis CyaA.
@en
P2093
Burkhard König
Frieder Kees
Jens Geduhn
Jens Schlossmann
Martin Göttle
Roland Seifert
Stefan Dove
Volkhard Kaever
Yuequan Shen
P2860
P304
P356
10.1021/BI100684G
P407
P50
P577
2010-07-01T00:00:00Z