Synaptic mutant huntingtin inhibits synapsin-1 phosphorylation and causes neurological symptoms.

Synaptic mutant huntingtin inhibits synapsin-1 phosphorylation and causes neurological symptoms.

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http://www.wikidata.org/entity/Q30441124
Transgenic animal models for study of the pathogenesis of Huntington's disease and therapyMutant huntingtin downregulates myelin regulatory factor-mediated myelin gene expression and affects mature oligodendrocytesAblation of huntingtin in adult neurons is nondeleterious but its depletion in young mice causes acute pancreatitis.Ubiquitin-activating enzyme activity contributes to differential accumulation of mutant huntingtin in brain and peripheral tissuesAged monkey brains reveal the role of ubiquitin-conjugating enzyme UBE2N in the synaptosomal accumulation of mutant huntingtin.Compartment-Dependent Degradation of Mutant Huntingtin Accounts for Its Preferential Accumulation in Neuronal ProcessesProteins that mediate protein aggregation and cytotoxicity distinguish Alzheimer's hippocampus from normal controls.Large Animal Models of Huntington's Disease.Striatal synaptosomes from Hdh140Q/140Q knock-in mice have altered protein levels, novel sites of methionine oxidation, and excess glutamate release after stimulationThe Role of Synapsins in Neurological Disorders.Huntingtin-associated protein-1 is a synapsin I-binding protein regulating synaptic vesicle exocytosis and synapsin I trafficking.Molecular insights into cortico-striatal miscommunications in Huntington's disease.
P2860

Synaptic mutant huntingtin inhibits synapsin-1 phosphorylation and causes neurological symptoms.

Item
http://www.wikidata.org/entity/Q30441124
description
2013 nî lūn-bûn
@nan
2013 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2013 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
name
Synaptic mutant huntingtin inh ...... causes neurological symptoms.
@ast
Synaptic mutant huntingtin inh ...... causes neurological symptoms.
@en
type
label
Synaptic mutant huntingtin inh ...... causes neurological symptoms.
@ast
Synaptic mutant huntingtin inh ...... causes neurological symptoms.
@en
prefLabel
Synaptic mutant huntingtin inh ...... causes neurological symptoms.
@ast
Synaptic mutant huntingtin inh ...... causes neurological symptoms.
@en
P1433
P1476
P2093
P2860
P304
P31
P356
P407
P433
P478
P577
P5875
P698
P921
P932
P356
P1433
P1476
Synaptic mutant huntingtin inh ...... causes neurological symptoms.
@en
P2093
P2860
P304
P31
P356
P407
P433
P478
P577
P5875
P698
P921
P932