A genome scan for modifiers of age at onset in Huntington disease: The HD MAPS study. - Wikidata - wikimedia - TriplyDB

A genome scan for modifiers of age at onset in Huntington disease: The HD MAPS study.

A genome scan for modifiers of age at onset in Huntington disease: The HD MAPS study.

http://www.wikidata.org/entity/Q30448206

about

Huntington's disease genetics The genetic epidemiology of neurodegenerative disease.Genetics and neuropathology of Huntington's disease Suppression of Somatic Expansion Delays the Onset of Pathophysiology in a Mouse Model of Huntington’s Disease Integration of β-catenin, sirtuin, and FOXO signaling protects from mutant huntingtin toxicity CAG repeat expansion in Huntington disease determines age at onset in a fully dominant fashion.Evidence for a modifier of onset age in Huntington disease linked to the HD gene in 4p16.Genome-wide significance for a modifier of age at neurological onset in Huntington's disease at 6q23-24: the HD MAPS study.Genetic background modulates behavioral impairments in R6/2 mice and suggests a role for dominant genetic modifiers in Huntington’s disease pathogenesis.Genetic analysis of the GRIK2 modifier effect in Huntington's disease.Genetic analysis of age at onset variation in spinocerebellar ataxia type 2.Identifying modifier genes of monogenic disease: strategies and difficulties.Huntington's disease and its therapeutic target genes: a global functional profile based on the HD Research Crossroads database Localization of sequence variations in PGC-1α influence their modifying effect in Huntington disease.MSH3 polymorphisms and protein levels affect CAG repeat instability in Huntington's disease mice CAG-repeat length and the age of onset in Huntington disease (HD): a review and validation study of statistical approaches.The V471A polymorphism in autophagy-related gene ATG7 modifies age at onset specifically in Italian Huntington disease patients.Mismatch repair genes Mlh1 and Mlh3 modify CAG instability in Huntington's disease mice: genome-wide and candidate approaches Normal-repeat-length polyglutamine peptides accelerate aggregation nucleation and cytotoxicity of expanded polyglutamine proteins Genome-wide association and systems genetic analyses of residual feed intake, daily feed consumption, backfat and weight gain in pigs miR-10b-5p expression in Huntington's disease brain relates to age of onset and the extent of striatal involvement Chromosome substitution strain assessment of a Huntington's disease modifier locus Identification of Genetic Factors that Modify Clinical Onset of Huntington's Disease.Novel therapeutic targets for Huntington's disease.Assessment of cortical and striatal involvement in 523 Huntington disease brains.New prospects and strategies for drug target discovery in neurodegenerative disorders Verbal episodic memory declines prior to diagnosis in Huntington's disease.Replication of twelve association studies for Huntington's disease residual age of onset in large Venezuelan kindreds.The gene coding for PGC-1alpha modifies age at onset in Huntington's Disease Venezuelan kindreds reveal that genetic and environmental factors modulate Huntington's disease age of onset Huntington disease in the South African population occurs on diverse and ethnically distinct genetic haplotypes Somatic expansion of the Huntington's disease CAG repeat in the brain is associated with an earlier age of disease onset.Triplet repeat length bias and variation in the human transcriptome.Established genetic risk factors do not distinguish early and later onset Crohn's disease.Modifier genes as therapeutics: the nuclear hormone receptor Rev Erb alpha (Nr1d1) rescues Nr2e3 associated retinal disease Molecular mechanisms and potential therapeutical targets in Huntington's disease.Genetic modifiers of neurological disease Choosing and using Drosophila models to characterize modifiers of Huntington's disease.DNA repair mechanisms in Huntington's disease.HDNetDB: A Molecular Interaction Database for Network-Oriented Investigations into Huntington's Disease.

P2860

Q22305906-FDEA0CE8-3531-499A-8701-2BBA0805EF49 Q22306301-7E462412-6491-44BB-8788-DFC0EC99BF00 Q27023050-110596BB-E4EA-493C-B36E-77B55B74AB74 Q27311065-7D6D6CB3-291C-4144-8DB4-59349489DD45 Q28507004-4B2D2AE7-8897-46E0-BC5E-7A4D65805B6E Q30422005-B9E89AC2-55EA-4BF0-8FED-008519276FFD Q30445013-A0C2BDD2-BCAE-48C6-83FD-96B5BFB4AE7C Q30445842-9F102175-09A5-4827-B6B2-631DFC7023C8 Q30467288-919AC835-52D9-42BB-9DC2-BF174999C7B6 Q33256755-A4929ACE-913E-4C4C-B5C1-DBD7BD5D471F Q33689165-2BFBECB9-2861-4CB1-A18C-5FCC0FA1ACC7 Q34025944-C387FA90-1102-4CB5-96EA-A3AB70AF44B3 Q34319766-603AB7BB-A8C2-4B90-B6B4-BE9141D01580 Q34498391-21AD9A9B-BC89-4C48-A93B-ACF2D3F59C76 Q34611199-BA5A7791-9313-41ED-80FC-6A83997A8A6F Q34624785-9C97114A-14E8-4EF9-9DE5-FD627341806C Q34873673-48367204-BC51-459C-B7E4-2B09C6513111 Q35034398-F95C1534-FC53-45AA-816A-BA7267B78E9E Q35080634-1434AA1E-441F-40F3-8790-DE49A70D81DD Q35095734-40BDB70C-FC0D-45F6-AC20-A04566B0D49A Q35147342-CA5DFE2F-0870-46FA-B69D-BEB599D07BC5 Q35214662-708EC46B-5CB5-4CD0-811C-EBD72A9EDD40 Q35915245-0E3EFCC6-80C6-412A-8F34-A4231A9F9F47 Q36219680-D6E6BD71-D554-46D8-BC9D-D3A998347F9A Q36310179-7B55EFC8-E55D-457A-BC8D-4F6DC158A796 Q36401411-AA13F28E-CB8F-48C1-B7B7-DAEA3DC40D87 Q36943511-D1F85437-9BFA-48B8-9572-0F05C7ADF4CE Q37004508-F8DAD3FB-3CCF-4541-AD16-4E0CE3A119FB Q37071213-3C8C9034-28DE-466E-8859-4FC7038E1B84 Q37073913-BCB180A2-2C05-4C7B-AC59-3515C1E4435C Q37186056-68DCE2D7-5175-4F25-BAC7-CE1738297E13 Q37272365-415E29AD-3177-4272-9562-1F3C27C2BE8D Q37351751-E519AE01-FC72-4260-BE3B-D5CCD81FCD7B Q37402237-1881931C-5A04-4F59-8D34-AA44F2C96C44 Q37539468-89DA07BF-5C7F-41D6-98FD-A16B47FF2048 Q37776087-52EEECB4-611E-41F5-AFE7-CD391242234F Q37830879-5D9E1936-179C-4862-A607-C65C5BD9F9DC Q38027948-53C282A9-1443-443C-8266-9A248E146198 Q38077667-555F5A86-C917-4B34-AAF6-91A4FF79B8FD Q38681978-FEA97D15-2315-40D6-87B7-859A59A4E122

P2860

A genome scan for modifiers of age at onset in Huntington disease: The HD MAPS study.

http://www.wikidata.org/entity/Q30448206

description

2003 nî lūn-bûn

@nan

2003 թուականի Օգոստոսին հրատարակուած գիտական յօդուած

@hyw

2003 թվականի օգոստոսին հրատարակված գիտական հոդված

@hy

2003年の論文

@ja

2003年論文

@yue

2003年論文

@zh-hant

2003年論文

@zh-hk

2003年論文

@zh-mo

2003年論文

@zh-tw

2003年论文

@wuu

name

A genome scan for modifiers of age at onset in Huntington disease: The HD MAPS study.

@ast

A genome scan for modifiers of age at onset in Huntington disease: The HD MAPS study.

@en

type

label

A genome scan for modifiers of age at onset in Huntington disease: The HD MAPS study.

@ast

A genome scan for modifiers of age at onset in Huntington disease: The HD MAPS study.

@en

prefLabel

A genome scan for modifiers of age at onset in Huntington disease: The HD MAPS study.

@ast

A genome scan for modifiers of age at onset in Huntington disease: The HD MAPS study.

@en

P1433

Q30448206-82155A84-449C-476C-B609-5AC4DB2FD8F9

P1476

Q30448206-E1EC4437-CFAD-4687-BEF8-425606C98CBF

P2093

Q30448206-0A1033E2-6AF9-467E-8906-80430025FEDD

Q30448206-130AA670-562A-458D-808A-C83DB994EC52

Q30448206-14FE1E2F-DE80-40A9-ABEE-8D804C8CFBB0

Q30448206-1BAA5372-40E5-401B-A6A3-D18886656D3E

Q30448206-2158D551-8BB2-424D-A6B6-A3655BD2078F

Q30448206-27093D06-65FD-472A-8D5D-8216E51C6B19

Q30448206-2E420F19-82EF-4AB7-AB8D-3DB703CD25C2

Q30448206-3824C3A8-FF44-4F10-AA7E-558A59ECB5AA

Q30448206-3A2F4564-42C0-4185-96A0-E5ED7B654966

Q30448206-3CF43116-2EF2-46A4-86BB-0051FEBCA4B0

P2860

Q30448206-186FA9DF-42BD-40C5-9203-68D08A55AE11

Q30448206-1E7E954D-64D7-492E-A51B-4B8CDAF067A8

Q30448206-217EFA1D-E689-492B-A32B-A0DF1E2E2DD0

Q30448206-30C106C1-2524-43A1-A8E5-0960F1A3CBE6

Q30448206-334E7964-615A-421B-B59C-33FDE7DC7857

Q30448206-46AFD058-2181-424A-AEC2-EA10AEEE4131

Q30448206-545A34E6-5C04-4900-8BDC-30639A93CA78

Q30448206-5DD309B8-B910-4521-896B-0F8907DCB090

Q30448206-695AFFDF-FDB7-420A-9CAE-39B8D63FCBB0

Q30448206-BC589EDB-2851-458D-B916-B021E5452F4D

P304

Q30448206-B6DD36CE-8698-4536-9BC3-24F268F32940

P31

Q30448206-26152E36-5542-4156-8565-1DC9E396BB3E

Q30448206-cfebe4fb-9a80-41d6-bcc7-ee2a89dad629

P356

Q30448206-FFBCABED-82A9-4E88-88EB-6AF57D4B23B9

P407

Q30448206-8F58E1AE-ECE1-4EC5-8299-94F24C7C76A5

P433

Q30448206-699CCEBF-A904-4E60-81EE-DB98D560DA52

P478

Q30448206-7D0F84D9-EEA7-4122-9CF5-FEC9471E58D9

P50

Q30448206-2B7B9CD7-23A0-4688-BD1C-610633FB85AA

Q30448206-368532AF-959F-4D6E-88CF-C191B4779443

Q30448206-3789F407-6293-49BD-8A28-F7B317E622F8

Q30448206-4A67FDC1-F5D1-46C4-B651-FE658B08FAE2

Q30448206-4F3777F0-4CA8-4205-BC46-62FC8DD1477E

Q30448206-60C3ACAC-2A10-4DB1-9C47-3D622EF3E2DE

Q30448206-62BB6CAD-D13B-41E4-8632-75B15556CAEF

Q30448206-69CA8386-6BB8-4FC2-A586-23520028A5DA

Q30448206-735EA52D-3D46-4EAF-BFA1-4EC09E34AEF1

Q30448206-9C30DD66-1796-4514-AEE4-F0A4A9A84661

P577

Q30448206-21DCD8CD-3FEC-4673-8E24-A8D987221183

P5875

Q30448206-40BD0603-F5FB-43B1-8B34-B61A9D70D7BC

P698

Q30448206-8E70A1E4-0564-48A2-B9EE-CA66F276A177

P921

Q30448206-1BBBA5BB-ACB6-4730-86B4-95F9808FD003

P932

Q30448206-86E6A86B-B948-40ED-99D5-521452A8351F

P356

P1433

American Journal of Human Genetics

P1476

A genome scan for modifiers of age at onset in Huntington disease: The HD MAPS study

@en

P2093

Adam Rosenblatt

http://www.w3.org/2001/XMLSchema#string

Alexandra Durr

http://www.w3.org/2001/XMLSchema#string

Ana L Russ

http://www.w3.org/2001/XMLSchema#string

Andrea Zanko

http://www.w3.org/2001/XMLSchema#string

Beth Knowlton

http://www.w3.org/2001/XMLSchema#string

Catherine Dodé

http://www.w3.org/2001/XMLSchema#string

David Mayo Cabrero

http://www.w3.org/2001/XMLSchema#string

Elisabeth W Almqvist

http://www.w3.org/2001/XMLSchema#string

Elizabeth McCusker

http://www.w3.org/2001/XMLSchema#string

Estrella Gómez-Tortosa

http://www.w3.org/2001/XMLSchema#string

P2860

Genotypes at the GluR6 kainate receptor locus are associated with variation in the age of onset of Huntington disease

A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes.

The relationship between trinucleotide (CAG) repeat length and clinical features of Huntington's disease

Parametric and nonparametric linkage analysis: a unified multipoint approach

Genetic dissection of complex traits: guidelines for interpreting and reporting linkage results

All LODs are not created equal.

Exact multipoint quantitative-trait linkage analysis in pedigrees by variance components.

Trinucleotide repeat length instability and age of onset in Huntington's disease.

The normal Huntington disease (HD) allele, or a closely linked gene, influences age at onset of HD

The likelihood of being affected with Huntington disease by a particular age, for a specific CAG size

P304

682-687

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1086/378133

http://www.w3.org/2001/XMLSchema#string

P407

P433

3

http://www.w3.org/2001/XMLSchema#string

P478

73

http://www.w3.org/2001/XMLSchema#string

P50

James F. Gusella

Andrea Novelletto

L. Adrienne Cupples

Richard H Myers

Jane S. Paulsen

Ryan R Brinkman

Marie-Helene Saint-Hilaire

Marcy E. MacDonald

Michael R. Hayden

P577

2003-08-01T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

10627747

http://www.w3.org/2001/XMLSchema#string

P698

12900792

http://www.w3.org/2001/XMLSchema#string

P921

Huntington disease

P932

1180695

http://www.w3.org/2001/XMLSchema#string