Replication in the amplified dihydrofolate reductase domain in CHO cells may initiate at two distinct sites, one of which is a repetitive sequence element.
about
The HeLa Pur factor binds single-stranded DNA at a specific element conserved in gene flanking regions and origins of DNA replicationSequence of cDNA comprising the human pur gene and sequence-specific single-stranded-DNA-binding properties of the encoded proteinRIP60, a mammalian origin-binding protein, enhances DNA bending near the dihydrofolate reductase origin of replicationPurification of RIP60 and RIP100, mammalian proteins with origin-specific DNA-binding and ATP-dependent DNA helicase activitiesThe matrix attachment region in the Chinese hamster dihydrofolate reductase origin of replication may be required for local chromatid separation.Initiation of replication in the Chinese hamster dihydrofolate reductase domain.Mammalian origins of replication.The plant amino acid mimosine may inhibit initiation at origins of replication in Chinese hamster cells.Initiation of DNA replication in the dihydrofolate reductase locus is confined to the early S period in CHO cells synchronized with the plant amino acid mimosine.A winding road to origin discoverySpecific signals at the 3' end of the DHFR gene define one boundary of the downstream origin of replication.Activation of a mammalian origin of replication by chromosomal rearrangement.Replication initiation sites are distributed widely in the amplified CHO dihydrofolate reductase domain.Radiation effects on DNA synthesis in a defined chromosomal replicon.Mapping of replication initiation sites in mammalian genomes by two-dimensional gel analysis: stabilization and enrichment of replication intermediates by isolation on the nuclear matrix.Multiple origins of replication in the dihydrofolate reductase amplicons of a methotrexate-resistant chinese hamster cell line.High-resolution mapping of replication fork movement through the amplified dihydrofolate reductase domain in CHO cells by in-gel renaturation analysis.Mimosine, a novel inhibitor of DNA replication, binds to a 50 kDa protein in Chinese hamster cellsCharacterizing replication intermediates in the amplified CHO dihydrofolate reductase domain by two novel gel electrophoretic techniques.Composite patterns in neutral/neutral two-dimensional gels demonstrate inefficient replication origin usage.The Chinese hamster dihydrofolate reductase origin consists of multiple potential nascent-strand start sitesLagging-strand, early-labelling, and two-dimensional gel assays suggest multiple potential initiation sites in the Chinese hamster dihydrofolate reductase originAttachment to the nuclear matrix mediates specific alterations in chromatin structure.A new class of reversible cell cycle inhibitors.Identification of primary initiation sites for DNA replication in the hamster dihydrofolate reductase gene initiation zone.Dynamics of association of origins of DNA replication with the nuclear matrix during the cell cycleModular sequence elements associated with origin regions in eukaryotic chromosomal DNA.Pre-replication complex proteins assemble at regions of low nucleosome occupancy within the Chinese hamster dihydrofolate reductase initiation zoneAmbiguities in results obtained with 2D gel replicon mapping techniquesAnalysis of the autonomous replication behavior in human cells of the dihydrofolate reductase putative chromosomal origin of replication.Emetine allows identification of origins of mammalian DNA replication by imbalanced DNA synthesis, not through conservative nucleosome segregationMultiple replication origins are used during Drosophila chorion gene amplificationSite-specific initiation of DNA replication in Xenopus egg extract requires nuclear structure.High-resolution mapping of the origin of DNA replication in the hamster dihydrofolate reductase gene domain by competitive PCR.Active mammalian replication origins are associated with a high-density cluster of mCpG dinucleotides.A mammalian origin of bidirectional DNA replication within the Chinese hamster RPS14 locus.Densely methylated DNA islands in mammalian chromosomal replication origins.Temporal order of DNA replication in the H-2 major histocompatibility complex of the mouse.Mapping an origin of DNA replication at a single-copy locus in exponentially proliferating mammalian cells.Isolation and cloning of putative mouse DNA replication initiation sites: binding to nuclear protein factors
P2860
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P2860
Replication in the amplified dihydrofolate reductase domain in CHO cells may initiate at two distinct sites, one of which is a repetitive sequence element.
description
1989 nî lūn-bûn
@nan
1989 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
1989 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
1989年の論文
@ja
1989年論文
@yue
1989年論文
@zh-hant
1989年論文
@zh-hk
1989年論文
@zh-mo
1989年論文
@zh-tw
1989年论文
@wuu
name
Replication in the amplified d ...... a repetitive sequence element.
@ast
Replication in the amplified d ...... a repetitive sequence element.
@en
type
label
Replication in the amplified d ...... a repetitive sequence element.
@ast
Replication in the amplified d ...... a repetitive sequence element.
@en
prefLabel
Replication in the amplified d ...... a repetitive sequence element.
@ast
Replication in the amplified d ...... a repetitive sequence element.
@en
P2860
P356
P1476
Replication in the amplified d ...... a repetitive sequence element.
@en
P2093
Anachkova B
P2860
P304
P356
10.1128/MCB.9.2.532
P407
P577
1989-02-01T00:00:00Z