Requirement for Ras/Rac1-mediated p38 and c-Jun N-terminal kinase signaling in Stat3 transcriptional activity induced by the Src oncoprotein.
about
Etk, a Btk family tyrosine kinase, mediates cellular transformation by linking Src to STAT3 activation.Protein kinase PKR is required for platelet-derived growth factor signaling of c-fos gene expression via Erks and Stat3.Janus kinases and signal transducers and activators of transcription: their roles in cytokine signaling, development and immunoregulation.Engaged for survival: From cadherin ligation to STAT3 activationThe formin/diaphanous-related protein, FHOS, interacts with Rac1 and activates transcription from the serum response elementProline-, glutamic acid-, and leucine-rich protein-1 is essential in growth factor regulation of signal transducers and activators of transcription 3 activation.Structure, function, and regulation of STAT proteinsTargeting signal-transducer-and-activator-of-transcription-3 for prevention and therapy of cancer: modern target but ancient solutionJNK-dependent Stat3 phosphorylation contributes to Akt activation in response to arsenic exposurePhosphotyrosyl peptides block Stat3-mediated DNA binding activity, gene regulation, and cell transformationThe v-Src SH3 domain facilitates a cell adhesion-independent association with focal adhesion kinase.Role of STAT3 in cancer metastasis and translational advances.A cell-permeable Stat3 SH2 domain mimetic inhibits Stat3 activation and induces antitumor cell effects in vitro.Hepatitis C virus (HCV) constitutively activates STAT-3 via oxidative stress: role of STAT-3 in HCV replicationAntitumor efficacy of the anti-interleukin-6 (IL-6) antibody siltuximab in mouse xenograft models of lung cancer.Inhibition of Janus kinase signaling during controlled mechanical ventilation prevents ventilation-induced diaphragm dysfunctionTranscription Factor STAT3 as a Novel Molecular Target for Cancer Prevention.JAK1 activates STAT3 activity in non-small-cell lung cancer cells and IL-6 neutralizing antibodies can suppress JAK1-STAT3 signalingAssociation of toxicity of sorafenib and sunitinib for human keratinocytes with inhibition of signal transduction and activator of transcription 3 (STAT3)Alpha-1 adrenergic receptor transactivates signal transducer and activator of transcription-3 (Stat3) through activation of Src and epidermal growth factor receptor (EGFR) in hepatocytes.Rac1 mediates STAT3 activation by autocrine IL-6The role of STATs in myeloid differentiation and leukemia.Control of myeloid differentiation and survival by Stats.Serine phosphorylation of STATs.Simultaneous tyrosine and serine phosphorylation of STAT3 transcription factor is involved in Rho A GTPase oncogenic transformationStat3-mediated Myc expression is required for Src transformation and PDGF-induced mitogenesis.Interleukin-10 targets p38 MAPK to modulate ARE-dependent TNF mRNA translation and limit intestinal pathology.Janus kinases: components of multiple signaling pathways.The synergy between stem cell factor (SCF) and granulocyte colony-stimulating factor (G-CSF): molecular basis and clinical relevance.G protein coupled receptor signaling through the Src and Stat3 pathway: role in proliferation and transformation.STAT proteins: novel molecular targets for cancer drug discovery.Alpha-interferon and its effects on signal transduction pathways.FRNK blocks v-Src-stimulated invasion and experimental metastases without effects on cell motility or growth.Withaferin A Inhibits STAT3 and Induces Tumor Cell Death in Neuroblastoma and Multiple MyelomaTargeted inhibition of Stat3 with a decoy oligonucleotide abrogates head and neck cancer cell growthThe R(h)oads to Stat3: Stat3 activation by the Rho GTPases.A novel small-molecule disrupts Stat3 SH2 domain-phosphotyrosine interactions and Stat3-dependent tumor processesDrosophila C-terminal Src kinase negatively regulates organ growth and cell proliferation through inhibition of the Src, Jun N-terminal kinase, and STAT pathways.Hirsutinolide Series Inhibit Stat3 Activity, Alter GCN1, MAP1B, Hsp105, G6PD, Vimentin, TrxR1, and Importin α-2 Expression, and Induce Antitumor Effects against Human Glioma.A novel nuclear Src and p300 signaling axis controls migratory and invasive behavior in pancreatic cancer.
P2860
Q22253232-DD87A5E3-2CE2-4984-9CFF-F74B1AE1BBFCQ24535156-6BB779EE-38E1-489C-8481-C9ED3C548B46Q24806655-82BD679A-B2C2-45E7-AFBE-BE1DE9278C4AQ27006477-BAAE3835-F83B-4AFB-B26A-5BCE3241ED56Q28190692-7F84CF67-A41F-4ED9-AD05-5018CC6CE27FQ28259770-4B0EC2F7-0A5D-47AA-9B84-C0F0E02B2FABQ28282800-A3651082-940D-4A63-AAFE-BBC9782D381CQ28291780-C6A25635-8E48-4EB1-A35E-066896068999Q28392308-281A090F-17D3-48D6-88A6-04986D0DEB1FQ28593921-29AEDE7F-BA12-42CF-99FE-07F7C34AFF3CQ30168345-A4C52928-DAFB-4924-896D-0B7350889BE4Q31142794-91056BCA-1ECE-4EBE-B0CB-A8D012BE4D1DQ33679564-63C4629E-A219-4B64-B791-A006518EFAD9Q33717232-1C1C0BA7-88A6-4D02-9B55-7A20934E9EF2Q33756818-773C0EA6-A3CE-4731-971D-664A5B3CFC1FQ33775184-96D41339-B678-43D5-A748-D743EAEC6AECQ33820278-A13426CE-849F-4372-9561-AAEAADA471E8Q33854898-6E85D48A-94EF-4843-90F5-CE2A37C7A311Q33889920-80A611AF-E943-49C2-975C-4D4E73B03138Q33919595-F683C9D4-675D-48E1-9C76-401133A7BF83Q33929488-E689C3DA-BB9E-4AF7-AFEA-FC8A6A554653Q33941366-088C1099-106D-4119-946A-D1E3D9D97C62Q33941411-79FBEDC2-F99E-47A3-BC6F-7AB875B9CC37Q33941422-25858FC0-C2D9-4691-B50D-0910634D5F86Q33948297-6DB61067-5F16-4656-8CE1-30AB33771BB0Q33951212-AD673F62-2111-4809-8884-D431F868CBE0Q34081023-BB45A58A-C60F-494C-86BA-757B5AB39212Q34103659-95973938-D322-49E1-9EB3-FB54F43112EDQ34142278-F1F9A2C8-233B-40FD-AA62-CD7B8E99A1A7Q34226011-163BBBEB-0E1C-4D2C-AD58-91F9AAB31266Q34293579-687B09E7-C9B7-43FF-9415-F5AACF98E3A0Q34351416-F03A3D91-EA61-4AAF-857C-A1B91E1F9EE8Q34360984-F88BCEBC-C306-4885-9595-0CAC041789E7Q34482178-BB8C413B-D8D3-4B29-9BE4-E9E07900830DQ34922227-86E2D41F-A376-41D9-A6BE-108B97CC4201Q35086590-460BD543-2A5F-4C6F-A65B-23DD401BF068Q35282743-9ACBCE7E-5849-4BE9-9D84-B3FCC08774C6Q35664007-54557F20-2C64-4196-9934-4B99E82D507BQ35761986-B9E37B73-11F0-4081-8E98-81F6734C7CD6Q35875878-09159706-E787-4DCF-91C3-6027B701F77A
P2860
Requirement for Ras/Rac1-mediated p38 and c-Jun N-terminal kinase signaling in Stat3 transcriptional activity induced by the Src oncoprotein.
description
1999 nî lūn-bûn
@nan
1999 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
name
Requirement for Ras/Rac1-media ...... nduced by the Src oncoprotein.
@ast
Requirement for Ras/Rac1-media ...... nduced by the Src oncoprotein.
@en
type
label
Requirement for Ras/Rac1-media ...... nduced by the Src oncoprotein.
@ast
Requirement for Ras/Rac1-media ...... nduced by the Src oncoprotein.
@en
prefLabel
Requirement for Ras/Rac1-media ...... nduced by the Src oncoprotein.
@ast
Requirement for Ras/Rac1-media ...... nduced by the Src oncoprotein.
@en
P2093
P2860
P356
P1476
Requirement for Ras/Rac1-media ...... nduced by the Src oncoprotein.
@en
P2093
L B Holzman
M Sekharam
P2860
P304
P356
10.1128/MCB.19.11.7519
P407
P577
1999-11-01T00:00:00Z