The motor activity of myosin-X promotes actin fiber convergence at the cell periphery to initiate filopodia formation.
about
Structural basis of cargo recognition by the myosin-X MyTH4-FERM domainRegulation of IRSp53-dependent filopodial dynamics by antagonism between 14-3-3 binding and SH3-mediated localization.Actin in dendritic spines: connecting dynamics to functionDynamic length regulation of sensory stereociliaFilopodia and adhesion in cancer cell motilityMyosin-X and diseaseThe myosin X motor is optimized for movement on actin bundles.Cargo recognition mechanism of myosin X revealed by the structure of its tail MyTH4-FERM tandem in complex with the DCC P3 domainAntiparallel coiled-coil-mediated dimerization of myosin XStructural basis of the myosin X PH1N-PH2-PH1C tandem as a specific and acute cellular PI(3,4,5)P3 sensorLever-arm mechanics of processive myosinsMyosin-10 and actin filaments are essential for mitotic spindle functionA myosin motor that selects bundled actin for motility.Unconventional myosin traffic in cells reveals a selective actin cytoskeleton.Myosin IIIa boosts elongation of stereocilia by transporting espin 1 to the plus ends of actin filaments.The motor protein myosin-X transports VE-cadherin along filopodia to allow the formation of early endothelial cell-cell contacts.Single-molecule stepping and structural dynamics of myosin X.Myosin-X induces filopodia by multiple elongation mechanism.Actin cross-link assembly and disassembly mechanics for alpha-Actinin and fascin.Cargo binding activates myosin VIIA motor function in cellsMyosin-X functions in polarized epithelial cells.Differential regulation of myosin X movements by its cargos, DCC and neogenin.Mutant p53-associated myosin-X upregulation promotes breast cancer invasion and metastasis.Myosin-X is critical for migratory ability of Xenopus cranial neural crest cells.A formin-nucleated actin aster concentrates cell wall hydrolases for cell fusion in fission yeast.Self-organization of waves and pulse trains by molecular motors in cellular protrusionsA Combination of Diffusion and Active Translocation Localizes Myosin 10 to the Filopodial TipActivated full-length myosin-X moves processively on filopodia with large steps toward diverse two-dimensional directionsThe stepping pattern of myosin X is adapted for processive motility on bundled actin.Intermolecular autophosphorylation regulates myosin IIIa activity and localization in parallel actin bundles.Distinct tissue distributions and subcellular localizations of differently phosphorylated forms of the myosin regulatory light chain in DrosophilaProbing intracellular motor protein activity using an inducible cargo trafficking assay.Myosin motor function: the ins and outs of actin-based membrane protrusions.Myosin-X: a MyTH-FERM myosin at the tips of filopodiaHeadless Myo10 is a negative regulator of full-length Myo10 and inhibits axon outgrowth in cortical neurons.Myosin X dimerization and its impact on cellular functions.Unconventional myosins acting unconventionally.Myosin-10 independently influences mitotic spindle structure and mitotic progressionInvolvement of headless myosin X in the motility of immortalized gonadotropin-releasing hormone neuronal cells.MyTH4-FERM myosins have an ancient and conserved role in filopod formation
P2860
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P2860
The motor activity of myosin-X promotes actin fiber convergence at the cell periphery to initiate filopodia formation.
description
2007 nî lūn-bûn
@nan
2007 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
name
The motor activity of myosin-X ...... initiate filopodia formation.
@ast
The motor activity of myosin-X ...... initiate filopodia formation.
@en
type
label
The motor activity of myosin-X ...... initiate filopodia formation.
@ast
The motor activity of myosin-X ...... initiate filopodia formation.
@en
prefLabel
The motor activity of myosin-X ...... initiate filopodia formation.
@ast
The motor activity of myosin-X ...... initiate filopodia formation.
@en
P2860
P356
P1476
The motor activity of myosin-X ...... o initiate filopodia formation
@en
P2093
Katsuhide Mabuchi
Mitsuo Ikebe
P2860
P304
P356
10.1083/JCB.200703178
P407
P577
2007-10-01T00:00:00Z