Gamma-actin is required for cytoskeletal maintenance but not development - Wikidata - wikimedia - TriplyDB

Gamma-actin is required for cytoskeletal maintenance but not development

Gamma-actin is required for cytoskeletal maintenance but not development

http://www.wikidata.org/entity/Q30488416

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Multiphasic analysis of whole exome sequencing data identifies a novel mutation of ACTG1 in a nonsyndromic hearing loss family Integrating the biophysical and molecular mechanisms of auditory hair cell mechanotransduction Targeted capture and next-generation sequencing identifies C9orf75, encoding taperin, as the mutated gene in nonsyndromic deafness DFNB79 The actin gene family: function follows isoform Review series: The cell biology of hearing Genetics of hearing and deafness Ubiquitin ligase TRIM3 controls hippocampal plasticity and learning by regulating synaptic γ-actin levels A membrane-type-1 matrix metalloproteinase (MT1-MMP)-discoidin domain receptor 1 axis regulates collagen-induced apoptosis in breast cancer cells The Stereociliary Paracrystal Is a Dynamic Cytoskeletal Scaffold In Vivo Evidence for changes in beta- and gamma-actin proportions during inner ear hair cell life Annexin A5 is the Most Abundant Membrane-Associated Protein in Stereocilia but is Dispensable for Hair-Bundle Development and Function The cytoskeleton and neurite initiation De novo mutations in the actin genes ACTB and ACTG1 cause Baraitser-Winter syndrome Severe forms of Baraitser-Winter syndrome are caused by ACTB mutations rather than ACTG1 mutations Hair bundle defects and loss of function in the vestibular end organs of mice lacking the receptor-like inositol lipid phosphatase PTPRQ The R109H variant of fascin-2, a developmentally regulated actin crosslinker in hair-cell stereocilia, underlies early-onset hearing loss of DBA/2J mice Developmental regulation of planar cell polarity and hair-bundle morphogenesis in auditory hair cells: lessons from human and mouse genetics.Whole animal knockout of smooth muscle alpha-actin does not alter excisional wound healing or the fibroblast-to-myofibroblast transition β-Actin and fascin-2 cooperate to maintain stereocilia length.Actin in hair cells and hearing loss.A corticosteroid-responsive transcription factor, promyelocytic leukemia zinc finger protein, mediates protection of the cochlea from acoustic trauma.Roles of the espin actin-bundling proteins in the morphogenesis and stabilization of hair cell stereocilia revealed in CBA/CaJ congenic jerker mice.In vivo and in vitro effects of two novel gamma-actin (ACTG1) mutations that cause DFNA20/26 hearing impairment.Ion-dependent polymerization differences between mammalian beta- and gamma-nonmuscle actin isoforms Actin-bundling protein TRIOBP forms resilient rootlets of hair cell stereocilia essential for hearing Mutational ataxia resulting from abnormal vestibular acquisition and processing is partially compensated for Progressive hearing loss and gradual deterioration of sensory hair bundles in the ears of mice lacking the actin-binding protein Eps8L2.Absence of plastin 1 causes abnormal maintenance of hair cell stereocilia and a moderate form of hearing loss in mice.γ-Actin plays a key role in endothelial cell motility and neovessel maintenance Live-cell imaging of actin dynamics reveals mechanisms of stereocilia length regulation in the inner ear.β-actin and γ-actin are each dispensable for auditory hair cell development but required for Stereocilia maintenance.Mechanotransduction current is essential for stability of the transducing stereocilia in mammalian auditory hair cells.Evidence for somatic gene conversion and deletion in bipolar disorder, Crohn's disease, coronary artery disease, hypertension, rheumatoid arthritis, type-1 diabetes, and type-2 diabetes.Smooth muscle α actin is specifically required for the maintenance of lactation A novel Atoh1 "self-terminating" mouse model reveals the necessity of proper Atoh1 level and duration for hair cell differentiation and viability.Functional null mutations of MSRB3 encoding methionine sulfoxide reductase are associated with human deafness DFNB74 Cells lacking β-actin are genetically reprogrammed and maintain conditional migratory capacity.Loss of γ-cytoplasmic actin triggers myofibroblast transition of human epithelial cells.Delayed embryonic development and impaired cell growth and survival in Actg1 null mice.Physiology, structure, and susceptibility to injury of skeletal muscle in mice lacking keratin 19-based and desmin-based intermediate filaments.

P2860

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P2860

Gamma-actin is required for cytoskeletal maintenance but not development

http://www.wikidata.org/entity/Q30488416

description

2009 nî lūn-bûn

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2009 թուականի Յունիսին հրատարակուած գիտական յօդուած

@hyw

2009 թվականի հունիսին հրատարակված գիտական հոդված

@hy

2009年の論文

@ja

2009年論文

@yue

2009年論文

@zh-hant

2009年論文

@zh-hk

2009年論文

@zh-mo

2009年論文

@zh-tw

2009年论文

@wuu

name

Gamma-actin is required for cytoskeletal maintenance but not development

@ast

Gamma-actin is required for cytoskeletal maintenance but not development

@en

type

label

Gamma-actin is required for cytoskeletal maintenance but not development

@ast

Gamma-actin is required for cytoskeletal maintenance but not development

@en

prefLabel

Gamma-actin is required for cytoskeletal maintenance but not development

@ast

Gamma-actin is required for cytoskeletal maintenance but not development

@en

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PNAS.0900221106

P1433

Proceedings of the National Academy of Sciences of the United States of America

P1476

Gamma-actin is required for cytoskeletal maintenance but not development

@en

P2093

Benjamin J Perrin

http://www.w3.org/2001/XMLSchema#string

Edward J Walsh

http://www.w3.org/2001/XMLSchema#string

Inna A Belyantseva

http://www.w3.org/2001/XMLSchema#string

James M Ervasti

http://www.w3.org/2001/XMLSchema#string

Karen H Friderici

http://www.w3.org/2001/XMLSchema#string

Kevin J Sonnemann

http://www.w3.org/2001/XMLSchema#string

Mei Zhu

http://www.w3.org/2001/XMLSchema#string

Ruben Stepanyan

http://www.w3.org/2001/XMLSchema#string

Thomas B Friedman

http://www.w3.org/2001/XMLSchema#string

P2860

A mutation of beta -actin that alters depolymerization dynamics is associated with autosomal dominant developmental malformations, deafness, and dystonia

An actin molecular treadmill and myosins maintain stereocilia functional architecture and self-renewal

Prestin is required for electromotility of the outer hair cell and for the cochlear amplifier

A mutation in the gamma actin 1 (ACTG1) gene causes autosomal dominant hearing loss (DFNA20/26)

Cytoplasmic gamma-actin is not required for skeletal muscle development but its absence leads to a progressive myopathy

The very large G-protein-coupled receptor VLGR1: a component of the ankle link complex required for the normal development of auditory hair bundles.

The dimensions and composition of stereociliary rootlets in mammalian cochlear hair cells: comparison between high- and low-frequency cells and evidence for a connection to the lateral membrane.

Mutations in the gamma-actin gene (ACTG1) are associated with dominant progressive deafness (DFNA20/26).

The active cochlea.

Functional anatomy of auditory brainstem nuclei: application to the anatomical basis of brainstem auditory evoked potentials.

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10.1073/PNAS.0900221106

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24

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106

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Gregory I Frolenkov

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2009-06-03T00:00:00Z

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26268084

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19497859

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