Fast adaptation and Ca2+ sensitivity of the mechanotransducer require myosin-XVa in inner but not outer cochlear hair cells.
about
Integrating the biophysical and molecular mechanisms of auditory hair cell mechanotransductionIs TMC1 the Hair Cell Mechanotransducer Channel?Assembly of hair bundles, an amazing problem for cell biologySensing sound: molecules that orchestrate mechanotransduction by hair cellsEps8 regulates hair bundle length and functional maturation of mammalian auditory hair cells.Deletion of Brg1 causes abnormal hair cell planer polarity, hair cell anchorage, and scar formation in mouse cochleaRegulation of stereocilia length by myosin XVa and whirlin depends on the actin-regulatory protein Eps8Tricellulin deficiency affects tight junction architecture and cochlear hair cells.Oncomodulin, an EF-Hand Ca2+ Buffer, Is Critical for Maintaining Cochlear Function in Mice.The murine catecholamine methyltransferase mTOMT is essential for mechanotransduction by cochlear hair cells.The physiology of mechanoelectrical transduction channels in hearing.Genetics of auditory mechano-electrical transduction.Molecular remodeling of tip links underlies mechanosensory regeneration in auditory hair cellsCalcium signaling in the cochlea - Molecular mechanisms and physiopathological implications.Actin-bundling protein TRIOBP forms resilient rootlets of hair cell stereocilia essential for hearingProgressive hearing loss and gradual deterioration of sensory hair bundles in the ears of mice lacking the actin-binding protein Eps8L2.Adaptation of mammalian auditory hair cell mechanotransduction is independent of calcium entry.Subunit determination of the conductance of hair-cell mechanotransducer channelsDefective Gpsm2/Gαi3 signalling disrupts stereocilia development and growth cone actin dynamics in Chudley-McCullough syndromeMutations in protocadherin 15 and cadherin 23 affect tip links and mechanotransduction in mammalian sensory hair cells.CIB2 interacts with TMC1 and TMC2 and is essential for mechanotransduction in auditory hair cells.Chaperone-enhanced purification of unconventional myosin 15, a molecular motor specialized for stereocilia protein traffickingTRPA1-mediated accumulation of aminoglycosides in mouse cochlear outer hair cells.The 133-kDa N-terminal domain enables myosin 15 to maintain mechanotransducing stereocilia and is essential for hearingDevelopment and localization of reverse-polarity mechanotransducer channels in cochlear hair cellsUsher proteins in inner ear structure and functionDefining features of the hair cell mechanoelectrical transducer channelMechanotransduction by hair cells: models, molecules, and mechanisms.Localisation of the mechanotransducer channels in mammalian cochlear hair cells provides clues to their gating.Rethinking how hearing happens.The actin-binding proteins eps8 and gelsolin have complementary roles in regulating the growth and stability of mechanosensory hair bundles of mammalian cochlear outer hair cells.The acquisition of mechano-electrical transducer current adaptation in auditory hair cells requires myosin VIPhosphoinositol-4,5-Bisphosphate Regulates Auditory Hair-Cell Mechanotransduction-Channel Pore Properties and Fast Adaptation.PIEZO2 as the anomalous mechanotransducer channel in auditory hair cells.A Model for Link Pruning to Establish Correctly Polarized and Oriented Tip Links in Hair Bundles.Mechanically Gated Ion Channels in Mammalian Hair Cells.
P2860
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P2860
Fast adaptation and Ca2+ sensitivity of the mechanotransducer require myosin-XVa in inner but not outer cochlear hair cells.
description
2009 nî lūn-bûn
@nan
2009 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
Fast adaptation and Ca2+ sensi ...... not outer cochlear hair cells.
@ast
Fast adaptation and Ca2+ sensi ...... not outer cochlear hair cells.
@en
type
label
Fast adaptation and Ca2+ sensi ...... not outer cochlear hair cells.
@ast
Fast adaptation and Ca2+ sensi ...... not outer cochlear hair cells.
@en
prefLabel
Fast adaptation and Ca2+ sensi ...... not outer cochlear hair cells.
@ast
Fast adaptation and Ca2+ sensi ...... not outer cochlear hair cells.
@en
P2860
P1476
Fast adaptation and Ca2+ sensi ...... not outer cochlear hair cells.
@en
P2093
Gregory I Frolenkov
Ruben Stepanyan
P2860
P304
P356
10.1523/JNEUROSCI.4566-08.2009
P407
P577
2009-04-01T00:00:00Z