Motor-independent targeting of CLASPs to kinetochores by CENP-E promotes microtubule turnover and poleward flux. - Wikidata - wikimedia - TriplyDB

Motor-independent targeting of CLASPs to kinetochores by CENP-E promotes microtubule turnover and poleward flux.

Motor-independent targeting of CLASPs to kinetochores by CENP-E promotes microtubule turnover and poleward flux.

http://www.wikidata.org/entity/Q30491189

about

The astrin-kinastrin/SKAP complex localizes to microtubule plus ends and facilitates chromosome alignment CLASP1, astrin and Kif2b form a molecular switch that regulates kinetochore-microtubule dynamics to promote mitotic progression and fidelity Regulation of kinetochore-microtubule attachments through homeostatic control during mitosis Reconstituting the kinetochore–microtubule interface: what, why, and how +TIPs: SxIPping along microtubule ends TPX2 phosphorylation maintains metaphase spindle length by regulating microtubule flux.Phosphorylation of EB2 by Aurora B and CDK1 ensures mitotic progression and genome stability.Chromosome congression is promoted by CENP-Q- and CENP-E-dependent pathways.Lateral and End-On Kinetochore Attachments Are Coordinated to Achieve Bi-orientation in Drosophila Oocytes Mitotic kinesin CENP-E promotes microtubule plus-end elongation.Multisite phosphorylation disrupts arginine-glutamate salt bridge networks required for binding of cytoplasmic linker-associated protein 2 (CLASP2) to end-binding protein 1 (EB1).Modulation of Golgi-associated microtubule nucleation throughout the cell cycle Kinetochore kinesin CENP-E is a processive bi-directional tracker of dynamic microtubule tips.A mitotic SKAP isoform regulates spindle positioning at astral microtubule plus ends.Finding the middle ground: how kinetochores power chromosome congression.Kinetochore-microtubule attachment throughout mitosis potentiated by the elongated stalk of the kinetochore kinesin CENP-E.Aurora B kinase controls the targeting of the Astrin-SKAP complex to bioriented kinetochores.A genomic toolkit to investigate kinesin and myosin motor function in cells.CLASP promotes microtubule rescue by recruiting tubulin dimers to the microtubule.Length-dependent anisotropic scaling of spindle shape Septin GTPases spatially guide microtubule organization and plus end dynamics in polarizing epithelia Kinetochore motors drive congression of peripheral polar chromosomes by overcoming random arm-ejection forces.Cdk1 and Plk1 mediate a CLASP2 phospho-switch that stabilizes kinetochore-microtubule attachments Chromosomes and cancer cells.Mechanisms of chromosomal instability.Mechanisms of Chromosome Congression during Mitosis.Anaphase A: Disassembling Microtubules Move Chromosomes toward Spindle Poles.Prevention and correction mechanisms behind anaphase synchrony: implications for the genesis of aneuploidy.Regulation of microtubule dynamics by TOG-domain proteins XMAP215/Dis1 and CLASP.Shaping microtubules into diverse patterns: molecular connections for setting up both ends.Kinetochores and disease: keeping microtubule dynamics in check!Regulatory mechanisms of kinetochore-microtubule interaction in mitosis.Maturation of the kinetochore-microtubule interface and the meaning of metaphase.Microtubule plus-ends within a mitotic cell are 'moving platforms' with anchoring, signalling and force-coupling roles.The molecular basis for kinesin functional specificity during mitosis.GSK3-mediated CLASP2 phosphorylation modulates kinetochore dynamics.The CLASP2 Protein Interaction Network in Adipocytes Links CLIP2 to AGAP3, CLASP2 to G2L1, MARK2, and SOGA1, and Identifies SOGA1 as a Microtubule-Associated Protein.Molecular mechanisms facilitating the initial kinetochore encounter with spindle microtubules.CLASP2 Links Reelin to the Cytoskeleton during Neocortical Development.CLASPs prevent irreversible multipolarity by ensuring spindle-pole resistance to traction forces during chromosome alignment.

P2860

Q24297335-F322816C-4FD4-4C46-B87C-635C94DA7F31 Q24300214-D8E7FE8A-E680-4B7F-88D8-7FA32263E4F3 Q26866233-AEC0E0A7-DB42-44F2-B300-6258AA902EEE Q27007105-4561FD4C-A0BD-4822-A1DA-F9552DC84268 Q27012425-E47D88B1-849B-4A34-BECB-F71A4D89C5CF Q27310325-E248A9DB-2A85-4206-8213-3EE207BD6683 Q27321639-5FE8590E-081A-444E-B18B-136A91E86E78 Q28116932-AD316533-37DC-43BE-AFEC-3707CF548BAB Q28550364-6CAF7C0E-B645-4D25-A858-C6EAF9C77811 Q30496766-EE8404ED-4BEE-42CF-9160-89DBF93DC58A Q30514537-BE12E0DA-8D33-440F-BB5B-F1D82F545E8F Q30536019-83D02394-46EA-4742-BB87-5D4E0443E793 Q30571387-FB4FD230-DF83-4772-B42E-4599E78DD27F Q30755578-85A5858A-B10A-4188-8E91-DD845A941252 Q33903518-FF27B3E2-6B97-4606-BEAC-DC971DCAF68D Q33975897-243ACA46-1C8D-449A-8E0F-18D3A84B14A9 Q34218832-B330C25C-FCBE-433D-8A6A-A3BF45BEBF09 Q34589246-335A9747-ABBF-4740-B63F-56229125951C Q34622487-2D1611DB-B16F-4D5D-B1AF-5E3AB5998D29 Q34698732-0116F856-C06D-49F7-AB53-48089CE23438 Q35130198-017659E2-FD1D-4FFB-8962-574F84AECCD9 Q35406761-4BEBD86B-ACD5-4BA4-A59F-B0C148DB71ED Q36317230-9F69790F-FDE0-40B7-A2B3-CFDC1B2D2A7F Q37165291-6ED59FDA-6CDA-43F4-BAF4-19B56897185B Q37193068-EE28C253-7AC5-462E-BF11-B525B3900C2C Q37728193-0B2E1598-58AA-42C0-8A94-B2B9A130BB86 Q37728197-D0F3A6B4-4713-4570-9FAA-C6589A17DE9F Q37838177-5B6526A3-0B73-412F-936F-A6C30FD3EC62 Q37904130-B8DA82C6-BE27-4E44-BFCC-6920BB692043 Q37948716-A5E11976-1D96-4383-9957-DDA88DEDF814 Q37971172-ED1AD8C3-086C-4F45-BFB7-AD1B8D5B89BE Q38023216-E90202B8-55D0-4783-81B2-2C15288F805A Q38026773-2A691AC3-8540-46DF-83D7-B38CD7D10F31 Q38066193-70F47D65-6584-4559-B776-D98F96D22ED0 Q38137982-C0A412AF-0F4C-4412-A13C-7532250454AE Q38715110-ACAC61AB-981C-4B01-9B54-FB1CE4597877 Q38760699-83193A45-59EC-490C-BDBD-ACC976D7C172 Q38818100-A6152FBC-CE1F-4ECB-A392-60F85E3A4D8A Q38912588-2F214BD9-61A7-49CF-80EC-5942D77E794B Q39401246-C38E345B-9218-49E4-8647-545454B0D9EA

P2860

Motor-independent targeting of CLASPs to kinetochores by CENP-E promotes microtubule turnover and poleward flux.

http://www.wikidata.org/entity/Q30491189

description

2009 nî lūn-bûn

@nan

2009 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած

@hyw

2009 թվականի սեպտեմբերին հրատարակված գիտական հոդված

@hy

2009年の論文

@ja

2009年学术文章

@wuu

2009年学术文章

@zh-cn

2009年学术文章

@zh-hans

2009年学术文章

@zh-my

2009年学术文章

@zh-sg

2009年學術文章

@yue

name

Motor-independent targeting of ...... le turnover and poleward flux.

@ast

Motor-independent targeting of ...... le turnover and poleward flux.

@en

type

label

Motor-independent targeting of ...... le turnover and poleward flux.

@ast

Motor-independent targeting of ...... le turnover and poleward flux.

@en

prefLabel

Motor-independent targeting of ...... le turnover and poleward flux.

@ast

Motor-independent targeting of ...... le turnover and poleward flux.

@en

P1433

Q30491189-3F1DBD4C-CC43-44DD-943E-8C5A413F0D4C

P1476

Q30491189-53CACC8F-A0D6-454F-8AE5-5DDDCE3631D5

P2093

Q30491189-5AA2E309-4C3A-4203-88BD-4994DA0A823F

Q30491189-96FA69A4-6ED4-49E9-A967-87B36EB3071F

Q30491189-9C1B6F77-9104-48EF-8B84-466A2C4F20E5

Q30491189-B70F7651-0B10-41BC-9E92-F12EE803919C

Q30491189-D9569657-D185-4AE7-9DBB-4E913326A14B

Q30491189-E6E09BCD-F863-4C74-9CE9-E2AA4620EF45

Q30491189-E72DFA81-8380-41E4-9E83-0F00526E6E98

Q30491189-FB442891-D189-4162-923D-7AE04C46B62D

P2860

Q30491189-00A91714-E80A-46EA-B075-CF28752803B1

Q30491189-01404493-2EFF-4119-B1F7-ABAFF1BCB114

Q30491189-0B310FF4-6590-408D-B352-614427891683

Q30491189-1AECEFA8-E404-4A05-987A-CCB982FF5A84

Q30491189-1EA95315-F95B-41FD-80ED-04BBA3C344B9

Q30491189-2186C78C-B53A-492D-8E3F-AFF3C2BE3B6E

Q30491189-2BAB760D-CEDB-4DA5-A688-A3D5E2A2A530

Q30491189-2E2C2C67-D415-493B-9017-E99416695E9A

Q30491189-2FEF6551-9949-462C-9447-425C0A268552

Q30491189-305BF4F6-EC2A-421A-99B2-355838785248

P304

Q30491189-01743BEA-42A9-4C21-9D19-069A774A2200

P31

Q30491189-FE723119-5E13-416E-BAEC-0EE00F95D150

P356

Q30491189-8BA1C71C-6112-4647-826D-44BC70C626BF

P407

Q30491189-76F8654C-9DD0-4CF9-AE84-D20B0A92728D

P433

Q30491189-336906D6-CE11-42E8-96CE-DC96F76D95C5

P478

Q30491189-AFEFB928-B193-4AE3-A747-C5CBFBA0EF05

P50

Q30491189-27259C41-ACA0-4DCC-BB0C-E61E1D4CEBE8

Q30491189-276073DA-2C5A-4A43-A5B5-A5C29B8D64F0

Q30491189-5C047235-1591-4CAA-9342-635B0BF76814

Q30491189-7DE218AF-8E55-4A94-8F4B-7BB2785620F3

P577

Q30491189-29D66063-08B8-4CCA-B00C-3005DB86F8D3

P5875

Q30491189-B31726FE-7D99-4850-8029-F639852502A5

P698

Q30491189-AD9F2219-ECD7-4BE5-B7D2-26498B4DA4A7

P921

Q30491189-A0B36499-443F-4BB3-8444-92E3DAF4A941

P932

Q30491189-84CAF999-FEEC-4961-B6DE-4A4CF5C5C757

P356

J.CUB.2009.07.059

P1433

Current Biology

P1476

Motor-independent targeting of ...... ule turnover and poleward flux

@en

P2093

Amity L Manning

http://www.w3.org/2001/XMLSchema#string

Ana R R Maia

http://www.w3.org/2001/XMLSchema#string

Andrej Shevchenko

http://www.w3.org/2001/XMLSchema#string

Anthony Hyman

http://www.w3.org/2001/XMLSchema#string

John R Yates

http://www.w3.org/2001/XMLSchema#string

Niels Galjart

http://www.w3.org/2001/XMLSchema#string

Stefano Maffini

http://www.w3.org/2001/XMLSchema#string

Zoltan Maliga

http://www.w3.org/2001/XMLSchema#string

P2860

Clasps are CLIP-115 and -170 associating proteins involved in the regional regulation of microtubule dynamics in motile fibroblasts

Unstable microtubule capture at kinetochores depleted of the centromere-associated protein CENP-F.

Mammalian CLASPs are required for mitotic spindle organization and kinetochore alignment

Mammalian CLASP1 and CLASP2 cooperate to ensure mitotic fidelity by regulating spindle and kinetochore function.

Human CLASP1 is an outer kinetochore component that regulates spindle microtubule dynamics

Asymmetric CLASP-dependent nucleation of noncentrosomal microtubules at the trans-Golgi network

MARK, a novel family of protein kinases that phosphorylate microtubule-associated proteins and trigger microtubule disruption

The conserved KMN network constitutes the core microtubule-binding site of the kinetochore

Genome stability is ensured by temporal control of kinetochore-microtubule dynamics

Plk4-induced centriole biogenesis in human cells

P304

1566-1572

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1016/J.CUB.2009.07.059

http://www.w3.org/2001/XMLSchema#string

P407

P433

18

http://www.w3.org/2001/XMLSchema#string

P478

19

http://www.w3.org/2001/XMLSchema#string

P50

Duane A Compton

Magno Junqueira

P577

2009-09-03T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

26792146

http://www.w3.org/2001/XMLSchema#string

P698

19733075

http://www.w3.org/2001/XMLSchema#string

P921

P932

2766669

http://www.w3.org/2001/XMLSchema#string