Myosin VI and its binding partner optineurin are involved in secretory vesicle fusion at the plasma membrane. - Wikidata - wikimedia - TriplyDB

Myosin VI and its binding partner optineurin are involved in secretory vesicle fusion at the plasma membrane.

Myosin VI and its binding partner optineurin are involved in secretory vesicle fusion at the plasma membrane.

http://www.wikidata.org/entity/Q30497821

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Mast cell mediators: their differential release and the secretory pathways involved Myosin motor proteins are involved in the final stages of the secretory pathways Loss of optineurin in vivo results in elevated cell death and alters axonal trafficking dynamics M98K-OPTN induces transferrin receptor degradation and RAB12-mediated autophagic death in retinal ganglion cells A novel amyotrophic lateral sclerosis mutation in OPTN induces ER stress and Golgi fragmentation in vitro.Autophagy receptors link myosin VI to autophagosomes to mediate Tom1-dependent autophagosome maturation and fusion with the lysosome.Myosin VI small insert isoform maintains exocytosis by tethering secretory granules to the cortical actin.Myosin 1b and F-actin are involved in the control of secretory granule biogenesis Myosin VI contributes to synaptic transmission and development at the Drosophila neuromuscular junction.E3-14.7K is recruited to TNF-receptor 1 and blocks TNF cytolysis independent from interaction with optineurin Absence of platelet phenotype in mice lacking the motor protein myosin Va Huntingtin is required for ER-to-Golgi transport and for secretory vesicle fusion at the plasma membrane.Genome-wide features of neuroendocrine regulation in Drosophila by the basic helix-loop-helix transcription factor DIMMED.Myosin VI deafness mutation prevents the initiation of processive runs on actin Optineurin deficiency in mice contributes to impaired cytokine secretion and neutrophil recruitment in bacteria-driven colitis Using genetic mouse models to gain insight into glaucoma: Past results and future possibilities.VAMP3/Syb and YKT6 are required for the fusion of constitutive secretory carriers with the plasma membrane.Dynamic exchange of myosin VI on endocytic structures Cellular and molecular biology of optineurin.A Rab3a-dependent complex essential for lysosome positioning and plasma membrane repair Myosin VI facilitates connexin 43 gap junction accretion.Toward an integrative view of Optineurin functions.Dynamic of ion channel expression at the plasma membrane of cardiomyocytes.Myosin VI and its cargo adaptors - linking endocytosis and autophagy.Emerging role of the scaffolding protein Dlg1 in vesicle trafficking.The cortical acto-Myosin network: from diffusion barrier to functional gateway in the transport of neurosecretory vesicles to the plasma membrane.ABHD17 proteins are novel protein depalmitoylases that regulate N-Ras palmitate turnover and subcellular localization.Kinetic Adaptations of Myosins for Their Diverse Cellular Functions A yeast model of optineurin proteinopathy reveals a unique aggregation pattern associated with cellular toxicity.Expression and localization of myosin VI in developing mouse spermatids.Kinetic properties and small-molecule inhibition of human myosin-6.MYO6 Regulates Spatial Organization of Signaling Endosomes Driving AKT Activation and Actin Dynamics.Myosin 1 controls membrane shape by coupling F-Actin to membrane.Enhanced optineurin E50K-TBK1 interaction evokes protein insolubility and initiates familial primary open-angle glaucoma.Myosin VI regulates actin dynamics and melanosome biogenesis.Myosins: Domain Organisation, Motor Properties, Physiological Roles and Cellular Functions.Defects in optineurin- and myosin VI-mediated cellular trafficking in amyotrophic lateral sclerosis.LRRK2 mediated Rab8a phosphorylation promotes lipid storage.Optineurin: A Coordinator of Membrane-Associated Cargo Trafficking and Autophagy.Dysfunction of Optineurin in Amyotrophic Lateral Sclerosis and Glaucoma.

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P2860

Myosin VI and its binding partner optineurin are involved in secretory vesicle fusion at the plasma membrane.

http://www.wikidata.org/entity/Q30497821

description

2010 nî lūn-bûn

@nan

2010 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի դեկտեմբերին հրատարակված գիտական հոդված

@hy

2010年の論文

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2010年論文

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2010年論文

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2010年論文

@zh-hk

2010年論文

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2010年論文

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2010年论文

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name

Myosin VI and its binding part ...... fusion at the plasma membrane.

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Myosin VI and its binding part ...... fusion at the plasma membrane.

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type

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Myosin VI and its binding part ...... fusion at the plasma membrane.

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Myosin VI and its binding part ...... fusion at the plasma membrane.

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Myosin VI and its binding part ...... fusion at the plasma membrane.

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Myosin VI and its binding part ...... fusion at the plasma membrane.

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MBC.E10-06-0553

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Molecular Biology of the Cell

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Myosin VI and its binding part ...... fusion at the plasma membrane

@en

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Folma Buss

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James R Sellers

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John Kendrick-Jones

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Lisa M Bond

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P2860

The localization of myosin VI at the golgi complex and leading edge of fibroblasts and its phosphorylation and recruitment into membrane ruffles of A431 cells after growth factor stimulation

Myosin VI is an actin-based motor that moves backwards

Optineurin links myosin VI to the Golgi complex and is involved in Golgi organization and exocytosis

rsly1 binding to syntaxin 5 is required for endoplasmic reticulum-to-Golgi transport but does not promote SNARE motif accessibility

How are the cellular functions of myosin VI regulated within the cell?

Rab8, a small GTPase involved in vesicular traffic between the TGN and the basolateral plasma membrane

Rab GTPases as coordinators of vesicle traffic

FIP-2, a coiled-coil protein, links Huntingtin to Rab8 and modulates cellular morphogenesis

Expression of mutant huntingtin blocks exocytosis in PC12 cells by depletion of complexin II

Adult-onset primary open-angle glaucoma caused by mutations in optineurin

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10.1091/MBC.E10-06-0553

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1

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