RBX1 (RING box protein 1) E3 ubiquitin ligase is required for genomic integrity by modulating DNA replication licensing proteins
about
Genetically engineered mouse models for functional studies of SKP1-CUL1-F-box-protein (SCF) E3 ubiquitin ligasesTargeting the overexpressed ROC1 induces G2 cell cycle arrest and apoptosis in esophageal cancer cellsTargeting the neddylation pathway to suppress the growth of prostate cancer cells: therapeutic implication for the men's cancer.Targeting cullin-RING ligases for cancer treatment: rationales, advances and therapeutic implications.The p21-dependent radiosensitization of human breast cancer cells by MLN4924, an investigational inhibitor of NEDD8 activating enzyme.Screening of UV-B-induced genes from apple peels by SSH: possible involvement of MdCOP1-mediated signaling cascade genes in anthocyanin accumulation.Knockdown of regulator of cullins-1 (ROC1) expression induces bladder cancer cell cycle arrest at the G2 phase and senescence.SAG/RBX2/ROC2 E3 ubiquitin ligase is essential for vascular and neural development by targeting NF1 for degradationRadiosensitization of human pancreatic cancer cells by MLN4924, an investigational NEDD8-activating enzyme inhibitor.Characterization of SCF-Complex during Bovine Preimplantation DevelopmentCDC-48/p97 coordinates CDT-1 degradation with GINS chromatin dissociation to ensure faithful DNA replication.Induction of cell senescence by targeting to Cullin-RING Ligases (CRLs) for effective cancer therapyRegulator of cullins-1 expression knockdown suppresses the malignant progression of muscle-invasive transitional cell carcinoma by regulating mTOR/DEPTOR pathway.Chromatin-associated degradation is defined by UBXN-3/FAF1 to safeguard DNA replication fork progression.Induction of autophagy and senescence by knockdown of ROC1 E3 ubiquitin ligase to suppress the growth of liver cancer cells.Molecular targets and mechanisms of radiosensitization using DNA damage response pathways.Suppression of tumor angiogenesis by targeting the protein neddylation pathway.Role of the ubiquitin-proteasome system in nervous system function and disease: using C. elegans as a dissecting tool.Radiosensitization of Cancer Cells by Inactivation of Cullin-RING E3 Ubiquitin Ligases.Cullin-RING Ligases as attractive anti-cancer targets.MLN4924 therapy as a novel approach in cancer treatment modalities.Biological determinants of radioresistance and their remediation in pancreatic cancer.Ubiquitin Ligases and Posttranslational Regulation of Energy in the Heart: The Hand that Feeds.Overexpression of CDT1 Is a Predictor of Poor Survival in Patients with Hepatocellular Carcinoma.A Large-Scale RNAi Screen Identifies SGK1 as a Key Survival Kinase for GBM Stem Cells.Protein neddylation and its alterations in human cancers for targeted therapy.RING box protein-1 gene involved in flagellar disassembly of Dunaliella salina.
P2860
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P2860
RBX1 (RING box protein 1) E3 ubiquitin ligase is required for genomic integrity by modulating DNA replication licensing proteins
description
2010 nî lūn-bûn
@nan
2010 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
RBX1 (RING box protein 1) E3 u ...... replication licensing proteins
@ast
RBX1 (RING box protein 1) E3 u ...... replication licensing proteins
@en
type
label
RBX1 (RING box protein 1) E3 u ...... replication licensing proteins
@ast
RBX1 (RING box protein 1) E3 u ...... replication licensing proteins
@en
prefLabel
RBX1 (RING box protein 1) E3 u ...... replication licensing proteins
@ast
RBX1 (RING box protein 1) E3 u ...... replication licensing proteins
@en
P2093
P2860
P356
P1476
RBX1 (RING box protein 1) E3 u ...... replication licensing proteins
@en
P2093
Jeremy S Bickel
Meredith A Morgan
Xiaochun Yu
P2860
P304
P356
10.1074/JBC.M110.188425
P407
P577
2010-11-29T00:00:00Z