Tumor necrosis factor-α synthesis inhibitor, 3,6'-dithiothalidomide, reverses behavioral impairments induced by minimal traumatic brain injury in mice - Wikidata - wikimedia - TriplyDB

Tumor necrosis factor-α synthesis inhibitor, 3,6'-dithiothalidomide, reverses behavioral impairments induced by minimal traumatic brain injury in mice

Tumor necrosis factor-α synthesis inhibitor, 3,6'-dithiothalidomide, reverses behavioral impairments induced by minimal traumatic brain injury in mice

http://www.wikidata.org/entity/Q30520539

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Studies of selective TNF inhibitors in the treatment of brain injury from stroke and trauma: a review of the evidence to date Excess cerebral TNF causing glutamate excitotoxicity rationalizes treatment of neurodegenerative diseases and neurogenic pain by anti-TNF agents Emerging therapies in traumatic brain injury Thioredoxin-Mimetic-Peptides Protect Cognitive Function after Mild Traumatic Brain Injury (mTBI)Cognitive Impairments Induced by Concussive Mild Traumatic Brain Injury in Mouse Are Ameliorated by Treatment with Phenserine via Multiple Non-Cholinergic and Cholinergic Mechanisms Exendin-4, a glucagon-like peptide-1 receptor agonist prevents mTBI-induced changes in hippocampus gene expression and memory deficits in mice Chronic post-traumatic headache: clinical findings and possible mechanisms.Exendin-4 attenuates blast traumatic brain injury induced cognitive impairments, losses of synaptophysin and in vitro TBI-induced hippocampal cellular degeneration Perispinal etanercept for post-stroke neurological and cognitive dysfunction: scientific rationale and current evidence Incretin mimetics as pharmacologic tools to elucidate and as a new drug strategy to treat traumatic brain injury Osteopontin expression in acute immune response mediates hippocampal synaptogenesis and adaptive outcome following cortical brain injury Deficient pain modulatory systems in patients with mild traumatic brain and chronic post-traumatic headache: implications for its mechanism Cognitive impairments accompanying rodent mild traumatic brain injury involve p53-dependent neuronal cell death and are ameliorated by the tetrahydrobenzothiazole PFT-α.Thalidomide Analogues Suppress Lipopolysaccharide-Induced Synthesis of TNF-α and Nitrite, an Intermediate of Nitric Oxide, in a Cellular Model of Inflammation Efficacy of N-acetyl cysteine in traumatic brain injury Transiently lowering tumor necrosis factor-α synthesis ameliorates neuronal cell loss and cognitive impairments induced by minimal traumatic brain injury in mice TNF-α protein synthesis inhibitor restores neuronal function and reverses cognitive deficits induced by chronic neuroinflammation.Mild Concussion, but Not Moderate Traumatic Brain Injury, Is Associated with Long-Term Depression-Like Phenotype in Mice Early intervention with a small molecule inhibitor for tumor necrosis factor-α prevents cognitive deficits in a triple transgenic mouse model of Alzheimer's disease Tumor necrosis factor-α synthesis inhibitor 3,6'-dithiothalidomide attenuates markers of inflammation, Alzheimer pathology and behavioral deficits in animal models of neuroinflammation and Alzheimer's disease 3,6'-Dithiothalidomide, a new TNF-α synthesis inhibitor, attenuates the effect of Aβ1-42 intracerebroventricular injection on hippocampal neurogenesis and memory deficit.Liraglutide is neurotrophic and neuroprotective in neuronal cultures and mitigates mild traumatic brain injury in mice.Blast traumatic brain injury-induced cognitive deficits are attenuated by preinjury or postinjury treatment with the glucagon-like peptide-1 receptor agonist, exendin-4.3,6'-dithiothalidomide improves experimental stroke outcome by suppressing neuroinflammation.Changes in mouse cognition and hippocampal gene expression observed in a mild physical- and blast-traumatic brain injury.Treatment of mild traumatic brain injury with an erythropoietin-mimetic peptide Pomalidomide mitigates neuronal loss, neuroinflammation, and behavioral impairments induced by traumatic brain injury in rat.Exendin-4 induced glucagon-like peptide-1 receptor activation reverses behavioral impairments of mild traumatic brain injury in mice Design, synthesis and biological assessment of novel N-substituted 3-(phthalimidin-2-yl)-2,6-dioxopiperidines and 3-substituted 2,6-dioxopiperidines for TNF-α inhibitory activity.Tumor necrosis factor-α potentiates long-term potentiation in the rat dentate gyrus after acute hypoxia.Inflammatory consequences in a rodent model of mild traumatic brain injury.Temporal course of changes in gene expression suggests a cytokine-related mechanism for long-term hippocampal alteration after controlled cortical impact.Treatment of traumatic brain injury with anti-inflammatory drugs.Novel GLP-1R/GIPR co-agonist "twincretin" is neuroprotective in cell and rodent models of mild traumatic brain injury.Repositioning drugs for traumatic brain injury - N-acetyl cysteine and Phenserine Inflammatory cytokine receptor blockade in a rodent model of mild traumatic brain injury.HOE-140, an antagonist of B2 receptor, protects against memory deficits and brain damage induced by moderate lateral fluid percussion injury in mice.Thalidomide attenuates learning and memory deficits induced by intracerebroventricular administration of streptozotocin in rats.Cytotoxicity of titanium dioxide nanoparticles in rat neuroglia cells.Erythropoietin regulates immune/inflammatory reaction and improves neurological function outcomes in traumatic brain injury.

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Tumor necrosis factor-α synthesis inhibitor, 3,6'-dithiothalidomide, reverses behavioral impairments induced by minimal traumatic brain injury in mice

http://www.wikidata.org/entity/Q30520539

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2011 nî lūn-bûn

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2011 թուականի Օգոստոսին հրատարակուած գիտական յօդուած

@hyw

2011 թվականի օգոստոսին հրատարակված գիտական հոդված

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2011年の論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年论文

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Tumor necrosis factor-α synthe ...... traumatic brain injury in mice

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Tumor necrosis factor-α synthe ...... traumatic brain injury in mice

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Tumor necrosis factor-α synthe ...... traumatic brain injury in mice

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Tumor necrosis factor-α synthe ...... traumatic brain injury in mice

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Tumor necrosis factor-α synthe ...... traumatic brain injury in mice

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J.1471-4159.2011.07377.X

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Journal of Neurochemistry

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Tumor necrosis factor-α synthe ...... traumatic brain injury in mice

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P2093

Barry J Hoffer

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Chaim G Pick

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David Tweedie

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Jeong Seon Yoon

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Nigel H Greig

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Renana Baratz

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Vardit Rubovitch

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Weiming Luo

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P2860

Thalidomide analogues as anticancer drugs

Does neuroinflammation fan the flame in neurodegenerative diseases?

Galectin-3 mediates post-ischemic tissue remodeling

Closed-head minimal traumatic brain injury produces long-term cognitive deficits in mice.

The recently identified P2Y-like receptor GPR17 is a sensor of brain damage and a new target for brain repair

Cell death mechanisms and modulation in traumatic brain injury.

Traumatic brain injury: an overview of pathobiology with emphasis on military populations.

Clinical pharmacokinetics of thalidomide.

TNF-alpha as a therapeutic target in inflammatory diseases, ischemia-reperfusion injury and trauma.

Genetic analysis of the role of tumor necrosis factor receptors in functional outcome after traumatic brain injury in mice.

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10.1111/J.1471-4159.2011.07377.X

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traumatic brain injury

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