Cell degeneration is not a primary causer for Connexin26 (GJB2) deficiency associated hearing loss.
about
Aberrant Cx26 hemichannels and keratitis-ichthyosis-deafness syndrome: insights into syndromic hearing lossCellular and Deafness Mechanisms Underlying Connexin Mutation-Induced Hearing Loss - A Common Hereditary Deafness.Assembly of the cochlear gap junction macromolecular complex requires connexin 26.Hypothesis of K+-Recycling Defect Is Not a Primary Deafness Mechanism for Cx26 (GJB2) DeficiencyPannexin 1 deficiency can induce hearing lossReduced Connexin26 in the Mature Cochlea Increases Susceptibility to Noise-Induced Hearing Lossin MiceConnexin26 (GJB2) deficiency reduces active cochlear amplification leading to late-onset hearing loss.Pannexin1 channels dominate ATP release in the cochlea ensuring endocochlear potential and auditory receptor potential generation and hearing.Active cochlear amplification is dependent on supporting cell gap junctionsA deafness mechanism of digenic Cx26 (GJB2) and Cx30 (GJB6) mutations: Reduction of endocochlear potential by impairment of heterogeneous gap junctional function in the cochlear lateral wall.Molecular composition and distribution of gap junctions in the sensory epithelium of the human cochlea-a super-resolution structured illumination microscopy (SR-SIM) study.Progressive age-dependence and frequency difference in the effect of gap junctions on active cochlear amplification and hearing.Gap junction mediated miRNA intercellular transfer and gene regulation: A novel mechanism for intercellular genetic communication.Connexin26 gap junction mediates miRNA intercellular genetic communication in the cochlea and is required for inner ear development.Deafness induced by Connexin 26 (GJB2) deficiency is not determined by endocochlear potential (EP) reduction but is associated with cochlear developmental disorders.Gap-junctional channel and hemichannel activity of two recently identified connexin 26 mutants associated with deafness.Knockout of Pannexin-1 Induces Hearing Loss.
P2860
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P2860
Cell degeneration is not a primary causer for Connexin26 (GJB2) deficiency associated hearing loss.
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2012 nî lūn-bûn
@nan
2012 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի սեպտեմբերին հրատարակված գիտական հոդված
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2012年の論文
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2012年学术文章
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2012年学术文章
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2012年学术文章
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2012年学术文章
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2012年学术文章
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2012年學術文章
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name
Cell degeneration is not a pri ...... iency associated hearing loss.
@ast
Cell degeneration is not a pri ...... iency associated hearing loss.
@en
type
label
Cell degeneration is not a pri ...... iency associated hearing loss.
@ast
Cell degeneration is not a pri ...... iency associated hearing loss.
@en
prefLabel
Cell degeneration is not a pri ...... iency associated hearing loss.
@ast
Cell degeneration is not a pri ...... iency associated hearing loss.
@en
P2093
P2860
P1433
P1476
Cell degeneration is not a pri ...... iency associated hearing loss.
@en
P2093
Chun Liang
Guang-Jin Lu
Hong-Bo Zhao
Liang Zong
P2860
P356
10.1016/J.NEULET.2012.08.085
P407
P577
2012-09-11T00:00:00Z