Transgenic expression of a dominant-negative connexin26 causes degeneration of the organ of Corti and non-syndromic deafness - Wikidata - wikimedia - TriplyDB

Transgenic expression of a dominant-negative connexin26 causes degeneration of the organ of Corti and non-syndromic deafness

Transgenic expression of a dominant-negative connexin26 causes degeneration of the organ of Corti and non-syndromic deafness

http://www.wikidata.org/entity/Q28191572

about

Life cycle of connexins in health and disease The role of connexins in ear and skin physiology - functional insights from disease-associated mutations Functional analysis and regulation of purified connexin hemichannels Genetics of hearing and deafness Aberrant Cx26 hemichannels and keratitis-ichthyosis-deafness syndrome: insights into syndromic hearing loss Cellular and Deafness Mechanisms Underlying Connexin Mutation-Induced Hearing Loss - A Common Hereditary Deafness.Mice with conditional deletion of Cx26 exhibit no vestibular phenotype despite secondary loss of Cx30 in the vestibular end organs Gap junctions and cochlear homeostasis Assembly of the cochlear gap junction macromolecular complex requires connexin 26.The human deafness-associated connexin 30 T5M mutation causes mild hearing loss and reduces biochemical coupling among cochlear non-sensory cells in knock-in mice.Hypothesis of K+-Recycling Defect Is Not a Primary Deafness Mechanism for Cx26 (GJB2) Deficiency ACEMg Diet Supplement Modifies Progression of Hereditary Deafness.Connexin 26 null mice exhibit spiral ganglion degeneration that can be blocked by BDNF gene therapy.Virally expressed connexin26 restores gap junction function in the cochlea of conditional Gjb2 knockout mice.Calcium signaling in the cochlea - Molecular mechanisms and physiopathological implications.Viral vector tropism for supporting cells in the developing murine cochlea.The sound of silence: mouse models for hearing loss Defining the cellular environment in the organ of Corti following extensive hair cell loss: a basis for future sensory cell replacement in the Cochlea.Reduced electromotility of outer hair cells associated with connexin-related forms of deafness: an in silico study of a cochlear network mechanism.Connexin30 deficiency causes instrastrial fluid-blood barrier disruption within the cochlear stria vascularis.Inner ear drug delivery for auditory applications.Gap-junction channels dysfunction in deafness and hearing loss.ATP-mediated cell-cell signaling in the organ of Corti: the role of connexin channels.Orphan glutamate receptor delta1 subunit required for high-frequency hearing.Cell degeneration is not a primary causer for Connexin26 (GJB2) deficiency associated hearing loss.Mouse otocyst transuterine gene transfer restores hearing in mice with connexin 30 deletion-associated hearing loss.Post-translational modifications of connexin26 revealed by mass spectrometry.Epithelial cell stretching and luminal acidification lead to a retarded development of stria vascularis and deafness in mice lacking pendrin.Connexin26 is responsible for anionic molecule permeability in the cochlea for intercellular signalling and metabolic communications TDP-43 potentiates alpha-synuclein toxicity to dopaminergic neurons in transgenic mice Temporal bone abnormalities in children with GJB2 mutations Dominant negative connexin26 mutation R75W causing severe hearing loss influences normal programmed cell death in postnatal organ of Corti.Deformation of the Outer Hair Cells and the Accumulation of Caveolin-2 in Connexin 26 Deficient Mice Molecular and physiological bases of the K+ circulation in the mammalian inner ear.Distinct Expression Patterns Of Causative Genes Responsible For Hereditary Progressive Hearing Loss In Non-Human Primate Cochlea.Ca2+ signaling in the inner ear.Cochleosaccular dysplasia associated with a connexin 26 mutation in keratitis-ichthyosis-deafness syndrome.Diverse deafness mechanisms of connexin mutations revealed by studies using in vitro approaches and mouse models.Connexin-26 mutations in deafness and skin disease.Ultrastructural pathological changes in the cochlear cells of connexin 26 conditional knockout mice.

P2860

Q24541428-45119B39-923F-49C3-AC07-30A6CCA34AF8 Q26827294-6B1200AF-A317-4E46-8354-86F630DEC22E Q26829380-8E853C41-FB59-4AB0-A373-692288404F15 Q26865293-5A171537-EB10-4352-888F-EF8D74175865 Q27002992-F107D5A6-40A5-42B9-9D94-E0AD1E99F7DC Q27009501-D003CE3E-FE1F-4C8E-8984-C8B0EB1F08CA Q27311137-747DBA1B-0A57-4709-9DDB-946A97F44316 Q28245955-96D1CF3F-410B-433F-9675-2B6424232143 Q28507910-B4C1DEE9-94B3-4208-A892-A67EF1B779B0 Q28748215-D5686B45-3F81-4213-B4B7-16F051A66BFA Q30354613-348DC1E2-C05F-48A8-A46A-C7FAC8999D72 Q30388543-4F45B7D6-B5B4-410E-912C-F44BAE9DF0D4 Q30417673-D5382CBF-8311-4251-9834-7B6D9061CA4A Q30435650-6A47B8CF-DE30-40D4-A2C2-29A19A0F9889 Q30465350-75A625BA-F819-4F95-93C0-4763E0B144D1 Q30466103-1AB884A0-7531-4D5C-BD67-DA6B98FB1F41 Q30467805-83CBB59C-9864-486E-92AB-C076DA9700D9 Q30471081-D2FE2517-03B3-46C7-84EA-A5F364522993 Q30472584-83B8D98E-4E6F-46D7-A4F2-C688EB26B3EC Q30479250-F347D04B-0FFA-4A58-B15A-32D519AD2738 Q30484636-6B65F9DD-8086-432C-A9D5-AA7A8E108853 Q30490087-DBB60C8E-B4C3-4904-977B-F9B907B92540 Q30495800-59CF9F93-12D7-4A45-B5FD-F0D396E66981 Q30500847-E23F5FBC-BE69-4068-A9C2-837E1D46BC0C Q30525586-844DBF4E-86C8-40C8-8DE2-C30001995905 Q30540472-7F0C2DAA-8FAD-4D4D-975B-05A31A5E385C Q33506159-9C635748-F417-4B49-8AD7-7342435D3571 Q33851694-4D60E06D-675F-4060-B61C-143EB75E3274 Q34415753-E6832D09-D7A0-475A-BFDF-5C9AFE765706 Q34648581-6D77E1E9-6518-42EB-B081-8FFEC22A26A3 Q34701181-E36D8008-94E2-4024-AC08-41EC4C7B1300 Q35081423-F4B471AC-A44F-4AFA-9AA2-4F502B269AAF Q35817242-0DB239AC-E056-4DB7-ABE3-ADAA7FA858E6 Q36600743-47D389FF-0DE8-468D-BF8A-2FFECA1F8ADA Q36621165-EC6B42AD-709D-4CD1-BF3A-857250B76A6E Q36786260-83C61CD9-057B-40CC-B5F5-5078CBC7011E Q36927052-21EA89E3-720B-48FB-8766-86BEBF0A223E Q37397290-19C83ED2-884E-4BDC-8F35-8341D7157F06 Q37638797-BC177C5A-7291-4E16-853C-BAFC38DB575B Q37693876-84666947-2EB9-4058-806D-7827C6BF040C

P2860

Transgenic expression of a dominant-negative connexin26 causes degeneration of the organ of Corti and non-syndromic deafness

http://www.wikidata.org/entity/Q28191572

description

2003 nî lūn-bûn

@nan

2003 թուականի Մայիսին հրատարակուած գիտական յօդուած

@hyw

2003 թվականի մայիսին հրատարակված գիտական հոդված

@hy

2003年の論文

@ja

2003年論文

@yue

2003年論文

@zh-hant

2003年論文

@zh-hk

2003年論文

@zh-mo

2003年論文

@zh-tw

2003年论文

@wuu

name

Transgenic expression of a dom ...... rti and non-syndromic deafness

@ast

Transgenic expression of a dom ...... rti and non-syndromic deafness

@en

Transgenic expression of a dom ...... rti and non-syndromic deafness

@nl

type

label

Transgenic expression of a dom ...... rti and non-syndromic deafness

@ast

Transgenic expression of a dom ...... rti and non-syndromic deafness

@en

Transgenic expression of a dom ...... rti and non-syndromic deafness

@nl

prefLabel

Transgenic expression of a dom ...... rti and non-syndromic deafness

@ast

Transgenic expression of a dom ...... rti and non-syndromic deafness

@en

Transgenic expression of a dom ...... rti and non-syndromic deafness

@nl

P1433

Q28191572-463D2CA1-FBFD-4891-8AC3-B75FC23BB05A

P1476

Q28191572-DB79609E-B636-4F7D-B28A-AFDCF1A15107

P2093

Q28191572-0A4A2865-792E-46B6-9997-D45D16A28655

Q28191572-10160ACC-E529-4C7C-AB1B-B91DFDFF0C25

Q28191572-278BBC30-1C79-4F87-AC3E-25A817E500A9

Q28191572-4A05E059-72EF-4844-9D8B-F3D4CE16A12A

Q28191572-5E0D597C-146D-4BAE-8FF8-476B4BA8AFE9

Q28191572-60838B76-8432-4458-BDA5-A5E01115BBC7

Q28191572-617EF10C-018C-48D8-AB17-356FC465B750

Q28191572-65582675-DC40-4716-BC31-BCE5F43B6609

Q28191572-BE27947B-2FFF-4626-BAC4-1108DDB6F2BB

Q28191572-C4A6B063-B167-48DB-926C-15D9E1714AAA

P304

Q28191572-C41C5A40-9B88-4C70-BE77-CD9A4380E39E

P31

Q28191572-106A2FFE-D77D-4398-B979-6FE30351C5F4

P356

Q28191572-D4A387BE-7BA4-4F0B-B2E3-83E61C5B626A

P407

Q28191572-BD5E1A1E-734E-495D-9569-843B9456CA1D

P433

Q28191572-799F8B3D-458A-4270-8AFB-D14EC57BEFDC

P478

Q28191572-70C75E4E-3AF4-4468-8F32-E3365CE791E5

P577

Q28191572-02979E2B-31A5-443A-934A-1167D9561047

P5875

Q28191572-99B3CEAF-D290-40E4-8ABF-A1BED05823E9

P698

Q28191572-0239D7D4-3304-4745-AAAD-09DE7F31F0CB

P356

P1433

Human Molecular Genetics

P1476

Transgenic expression of a dom ...... rti and non-syndromic deafness

@en

P2093

Akiko Ichinohe

http://www.w3.org/2001/XMLSchema#string

An-Ping Xia

http://www.w3.org/2001/XMLSchema#string

Kanako Kojima

http://www.w3.org/2001/XMLSchema#string

Katsuhisa Ikeda

http://www.w3.org/2001/XMLSchema#string

Masaaki Suzuki

http://www.w3.org/2001/XMLSchema#string

Shigeo Kure

http://www.w3.org/2001/XMLSchema#string

Takayuki Kudo

http://www.w3.org/2001/XMLSchema#string

Toshimitsu Kobayashi

http://www.w3.org/2001/XMLSchema#string

Yoichi Matsubara

http://www.w3.org/2001/XMLSchema#string

Yoichi Suzuki

http://www.w3.org/2001/XMLSchema#string

P304

995-1004

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1093/HMG/DDG116

http://www.w3.org/2001/XMLSchema#string

P407

P433

9

http://www.w3.org/2001/XMLSchema#string

P478

12

http://www.w3.org/2001/XMLSchema#string

P577

2003-05-01T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

277539512

http://www.w3.org/2001/XMLSchema#string

P698

12700168

http://www.w3.org/2001/XMLSchema#string