Disruption of the non-canonical Wnt gene PRICKLE2 leads to autism-like behaviors with evidence for hippocampal synaptic dysfunction
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Advancing the understanding of autism disease mechanisms through geneticsWnt signaling networks in autism spectrum disorder and intellectual disabilityTranslational Mouse Models of Autism: Advancing Toward Pharmacological Therapeutics.Seizures are regulated by ubiquitin-specific peptidase 9 X-linked (USP9X), a de-ubiquitinaseLocalization and behaviors in null mice suggest that ASIC1 and ASIC2 modulate responses to aversive stimuli.WISP1: Clinical insights for a proliferative and restorative member of the CCN family3p14 De Novo Interstitial Microdeletion in a Patient with Intellectual Disability and Autistic Features with Language Impairment: A Comparison with Similar CasesControl of vertebrate core planar cell polarity protein localization and dynamics by Prickle 2.Wnt-5a-regulated miR-101b controls COX2 expression in hippocampal neuronsModeling Smith-Lemli-Opitz syndrome with induced pluripotent stem cells reveals a causal role for Wnt/β-catenin defects in neuronal cholesterol synthesis phenotypesA rare WNT1 missense variant overrepresented in ASD leads to increased Wnt signal pathway activation.Evidence for opposing roles of Celsr3 and Vangl2 in glutamatergic synapse formation.Wnt-related SynGAP1 is a neuroprotective factor of glutamatergic synapses against Aβ oligomers.Dendrite and spine modifications in autism and related neurodevelopmental disorders in patients and animal models.Neurodevelopmental Perspectives on Wnt Signaling in Psychiatry.Molecular genetics and targeted therapy of WNT-related human diseases (Review).The Planar Cell Polarity Transmembrane Protein Vangl2 Promotes Dendrite, Spine and Glutamatergic Synapse Formation in the Mammalian Forebrain.Targeted sequencing and functional analysis reveal brain-size-related genes and their networks in autism spectrum disorders.Response to Sandford et al.: PRICKLE2 Variants in Epilepsy: A Call for Precision Medicine.Activity-Dependent Neuroplasticity Induced by an Enriched Environment Reverses Cognitive Deficits in Scribble Deficient Mouse.A novel relationship for schizophrenia, bipolar and major depressive disorder Part 3: Evidence from chromosome 3 high density association screen.Hub connectivity, neuronal diversity, and gene expression in the Caenorhabditis elegans connectome.[The multiple links between cilia and planar cell polarity].FoxO proteins in the nervous system.The Wnt Signaling Pathway and Related Therapeutic Drugs in Autism Spectrum Disorder.Defective motile cilia in Prickle2-deficient mice
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P2860
Disruption of the non-canonical Wnt gene PRICKLE2 leads to autism-like behaviors with evidence for hippocampal synaptic dysfunction
description
2013 nî lūn-bûn
@nan
2013 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2013 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
name
Disruption of the non-canonica ...... ppocampal synaptic dysfunction
@ast
Disruption of the non-canonica ...... ppocampal synaptic dysfunction
@en
type
label
Disruption of the non-canonica ...... ppocampal synaptic dysfunction
@ast
Disruption of the non-canonica ...... ppocampal synaptic dysfunction
@en
prefLabel
Disruption of the non-canonica ...... ppocampal synaptic dysfunction
@ast
Disruption of the non-canonica ...... ppocampal synaptic dysfunction
@en
P2093
P2860
P356
P1433
P1476
Disruption of the non-canonica ...... ppocampal synaptic dysfunction
@en
P2093
A G Bassuk
A J Shepherd
B W Darbro
D P Mohapatra
E Campbell
G B Richerson
H El-Shanti
J A Wemmie
J D Ulrich
P2860
P2888
P304
P356
10.1038/MP.2013.71
P407
P577
2013-05-28T00:00:00Z