Rapid microtiter assays for poxvirus topoisomerase, mammalian type IB topoisomerase and HIV-1 integrase: application to inhibitor isolation
about
Peptides that bind the HIV-1 integrase and modulate its enzymatic activity--kinetic studies and mode of actionSpecific inhibition of human immunodeficiency virus type 1 (HIV-1) integration in cell culture: putative inhibitors of HIV-1 integraseHomogeneous high-throughput screening assays for HIV-1 integrase 3beta-processing and strand transfer activities.Peptides derived from HIV-1 integrase that bind Rev stimulate viral genome integration.A nonradioactive plate-based assay for stimulators of nonspecific DNA nicking by HIV-1 integrase and other nucleases.Metal binding by the D,DX35E motif of human immunodeficiency virus type 1 integrase: selective rescue of Cys substitutions by Mn2+ in vitroDevelopment of a human immunodeficiency virus vector-based, single-cycle assay for evaluation of anti-integrase compoundsThe discovery of allyltyrosine based tripeptides as selective inhibitors of the HIV-1 integrase strand-transfer reaction.Preclinical evaluation of 1H-benzylindole derivatives as novel human immunodeficiency virus integrase strand transfer inhibitorsAzido-containing diketo acid derivatives inhibit human immunodeficiency virus type 1 integrase in vivo and influence the frequency of deletions at two-long-terminal-repeat-circle junctions.Lamellarins and related pyrrole-derived alkaloids from marine organisms.Comparison of metal-dependent catalysis by HIV-1 and ASV integrase proteins using a new and rapid, moderate throughput assay for joining activity in solutionOligonucleotide-based assays for integrase activity.Discovery of HIV-1 integrase inhibitors: pharmacophore mapping, virtual screening, molecular docking, synthesis, and biological evaluation.Green tea constituents (-)-epigallocatechin-3-gallate (EGCG) and gallic acid induce topoisomerase I- and topoisomerase II-DNA complexes in cells mediated by pyrogallol-induced hydrogen peroxide.A versatile and practical synthesis toward the development of novel HIV-1 integrase inhibitors.Integration of HIV-1 DNA is regulated by interplay between viral rev and cellular LEDGF/p75 proteins.Lens epithelium-derived growth factor/p75 interacts with the transposase-derived DDE domain of PogZ.A high-throughput assay for Tn5 Tnp-induced DNA cleavage.Design, Synthesis and antiHIV activity of Novel Isatine-Sulphonamides.Variola virus topoisomerase: DNA cleavage specificity and distribution of sites in Poxvirus genomes.Development of an AlphaScreen-based HIV-1 integrase dimerization assay for discovery of novel allosteric inhibitors.Regulation of catalysis by the smallpox virus topoisomerase.Denigrins A-C: new antitubercular 3,4-diarylpyrrole alkaloids from Dendrilla nigra.Monitoring the HIV-1 integrase enzymatic activity using atomic force microscopy in a 2LTR system.Development and application of a high-throughput screening assay for HIV-1 integrase enzyme activities.
P2860
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P2860
Rapid microtiter assays for poxvirus topoisomerase, mammalian type IB topoisomerase and HIV-1 integrase: application to inhibitor isolation
description
2000 nî lūn-bûn
@nan
2000 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2000年の論文
@ja
2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
name
Rapid microtiter assays for po ...... ication to inhibitor isolation
@ast
Rapid microtiter assays for po ...... ication to inhibitor isolation
@en
type
label
Rapid microtiter assays for po ...... ication to inhibitor isolation
@ast
Rapid microtiter assays for po ...... ication to inhibitor isolation
@en
prefLabel
Rapid microtiter assays for po ...... ication to inhibitor isolation
@ast
Rapid microtiter assays for po ...... ication to inhibitor isolation
@en
P2093
P2860
P356
P1476
Rapid microtiter assays for po ...... ication to inhibitor isolation
@en
P2093
P2860
P304
P356
10.1093/NAR/28.24.4884
P407
P577
2000-12-01T00:00:00Z