Random mutagenesis of human cytochrome p450 2A6 and screening with indole oxidation products.
about
Structural insight into the altered substrate specificity of human cytochrome P450 2A6 mutantsEngineering cytochrome P450 biocatalysts for biotechnology, medicine and bioremediationCytochrome P450 enzymes in the generation of commercial products.Analysis of coumarin 7-hydroxylation activity of cytochrome P450 2A6 using random mutagenesis.Expansion of substrate specificity of cytochrome P450 2A6 by random and site-directed mutagenesis.Identification of amino acid residues involved in 4-chloroindole 3-hydroxylation by cytochrome P450 2A6 using screening of random libraries.Directed-evolution analysis of human cytochrome P450 2A6 for enhanced enzymatic catalysis.Optimization of fermentation conditions for P450 BM-3 monooxygenase production by hybrid design methodologyRe-engineering cytochrome P450 2B11dH for enhanced metabolism of several substrates including the anti-cancer prodrugs cyclophosphamide and ifosfamide.Exploring the potential of xenobiotic-metabolising enzymes as biocatalysts: evolving designer catalysts from polyfunctional cytochrome P450 enzymes.Indole peroxygenase activity of indoleamine 2,3-dioxygenaseEffect of CYP2A13 active site mutation N297A on metabolism of coumarin and tobacco-specific nitrosamines.Evaluation of Luminescent P450 Analysis for Directed Evolution of Human CYP4A11Directed evolution of cytochrome P450 enzymes for biocatalysis: exploiting the catalytic versatility of enzymes with relaxed substrate specificity.Identification and analysis of conserved sequence motifs in cytochrome P450 family 2. Functional and structural role of a motif 187RFDYKD192 in CYP2B enzymes.Oxidation of pyrene, 1-hydroxypyrene, 1-nitropyrene and 1-acetylpyrene by human cytochrome P450 2A13Mutations of toluene-4-monooxygenase that alter regiospecificity of indole oxidation and lead to production of novel indigoid pigments.Analysis of Cytochrome P450 Conserved Sequence Motifs between Helices E and H: Prediction of Critical Motifs and Residues in Enzyme Functions.Kinetic analysis of oxidation of coumarins by human cytochrome P450 2A6.Multicomponent phenol hydroxylase-catalysed formation of hydroxyindoles and dyestuffs from indole and its derivatives.Screening for cytochrome p450 reactivity by harnessing catalase as reporter enzyme.Identification and characterization of an indigo-producing oxygenase involved in indole 3-acetic acid utilization by Acinetobacter baumannii.Biodegradation and Biotransformation of Indole: Advances and Perspectives
P2860
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P2860
Random mutagenesis of human cytochrome p450 2A6 and screening with indole oxidation products.
description
2001 nî lūn-bûn
@nan
2001 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
Random mutagenesis of human cy ...... ith indole oxidation products.
@ast
Random mutagenesis of human cy ...... ith indole oxidation products.
@en
type
label
Random mutagenesis of human cy ...... ith indole oxidation products.
@ast
Random mutagenesis of human cy ...... ith indole oxidation products.
@en
prefLabel
Random mutagenesis of human cy ...... ith indole oxidation products.
@ast
Random mutagenesis of human cy ...... ith indole oxidation products.
@en
P2093
P356
P1476
Random mutagenesis of human cy ...... ith indole oxidation products.
@en
P2093
F P Guengerich
K Nakamura
M V Martin
P356
10.1006/ABBI.2001.2569
P407
P577
2001-11-01T00:00:00Z