Structure and regulation of the mouse ing1 gene. Three alternative transcripts encode two phd finger proteins that have opposite effects on p53 function.
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Role of the Sin3-histone deacetylase complex in growth regulation by the candidate tumor suppressor p33(ING1).Histone H3K4me3 Binding Is Required for the DNA Repair and Apoptotic Activities of ING1 Tumor SuppressorThree yeast proteins related to the human candidate tumor suppressor p33(ING1) are associated with histone acetyltransferase activities.Differential association of products of alternative transcripts of the candidate tumor suppressor ING1 with the mSin3/HDAC1 transcriptional corepressor complexExpression of novel ING variants is regulated by thyroid hormone in the Xenopus laevis tadpole.ING proteins as potential anticancer drug targets.Deletion of p37Ing1 in mice reveals a p53-independent role for Ing1 in the suppression of cell proliferation, apoptosis, and tumorigenesis.p37Ing1b regulates B-cell proliferation and cooperates with p53 to suppress diffuse large B-cell lymphomagenesisThe ING gene family in the regulation of cell growth and tumorigenesis.Yng2p-dependent NuA4 histone H4 acetylation activity is required for mitotic and meiotic progression.Allelic loss and reduced expression of the ING3, a candidate tumor suppressor gene at 7q31, in human head and neck cancers.Deletion of the RAG2 C terminus leads to impaired lymphoid development in miceLeucine zipper-like domain is required for tumor suppressor ING2-mediated nucleotide excision repair and apoptosis.Inhibitory effect of tumor suppressor p33(ING1b) and its synergy with p53 gene in hepatocellular carcinomaThe role of the tumour suppressor p33 ING1b in human neoplasiaDownregulation of nuclear expression of the p33(ING1b) inhibitor of growth protein in invasive carcinoma of the breast.Chromatin structure following UV-induced DNA damage-repair or death?ING function in apoptosis in diverse model systems.Reviewing the current classification of inhibitor of growth family proteins.Structural insight into histone recognition by the ING PHD fingersRegulation of p53 by ING family members in suppression of tumor initiation and progression.ING1 and ING2: multifaceted tumor suppressor genes.Ing1 functions in DNA demethylation by directing Gadd45a to H3K4me3.Role of an ING1 growth regulator in transcriptional activation and targeted histone acetylation by the NuA4 complex.Exploration of novel motifs derived from mouse cDNA sequences.Human inhibitor of growth 1 inhibits hepatoma cell growth and influences p53 stability in a variant-dependent manner.Expression of the novel tumour suppressor p33(ING1)is independent of p53.The ING tumor suppressors in cellular senescence and chromatin.Ing1 mediates p53 accumulation and chromatin modification in response to oncogenic stress.ING1b decreases cell proliferation through p53-dependent and -independent mechanisms.Melanoma cells can tolerate high levels of transcriptionally active endogenous p53 but are sensitive to retrovirus-transduced p53.
P2860
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P2860
Structure and regulation of the mouse ing1 gene. Three alternative transcripts encode two phd finger proteins that have opposite effects on p53 function.
description
1999 nî lūn-bûn
@nan
1999 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年学术文章
@wuu
1999年学术文章
@zh-cn
1999年学术文章
@zh-hans
1999年学术文章
@zh-my
1999年学术文章
@zh-sg
1999年學術文章
@yue
name
Structure and regulation of th ...... osite effects on p53 function.
@ast
Structure and regulation of th ...... osite effects on p53 function.
@en
type
label
Structure and regulation of th ...... osite effects on p53 function.
@ast
Structure and regulation of th ...... osite effects on p53 function.
@en
prefLabel
Structure and regulation of th ...... osite effects on p53 function.
@ast
Structure and regulation of th ...... osite effects on p53 function.
@en
P2093
P2860
P356
P1476
Structure and regulation of th ...... osite effects on p53 function.
@en
P2093
Diatchenko L
Garkavtsev IV
Grigorian IA
Zeremski M
P2860
P304
32172-32181
P356
10.1074/JBC.274.45.32172
P407
P577
1999-11-01T00:00:00Z