Adozelesin triggers DNA damage response pathways and arrests SV40 DNA replication through replication protein A inactivation.
about
Sumoylation of the novel protein hRIP{beta} is involved in replication protein A deposition in PML nuclear bodiesThe 32-kilodalton subunit of replication protein A interacts with menin, the product of the MEN1 tumor suppressor genePhosphorylation of the replication protein A large subunit in the Saccharomyces cerevisiae checkpoint responseCell-free and cellular activities of a DNA sequence selective hairpin polyamide-CBI conjugateThe interaction of p53 with replication protein A mediates suppression of homologous recombinationUV-induced hyperphosphorylation of replication protein a depends on DNA replication and expression of ATM protein.Regulation of dna replication after heat shock by replication protein a-nucleolin interactions.DNA damage induced hyperphosphorylation of replication protein A. 2. Characterization of DNA binding activity, protein interactions, and activity in DNA replication and repair.The majority of human replication protein A remains complexed throughout the cell cycle.Replication protein A is sequentially phosphorylated during meiosis.Replication protein A (RPA) phosphorylation prevents RPA association with replication centers.DNA replication defects, spontaneous DNA damage, and ATM-dependent checkpoint activation in replication protein A-deficient cells.Novel checkpoint response to genotoxic stress mediated by nucleolin-replication protein a complex formation.The meiosis-specific protein kinase Ime2 directs phosphorylation of replication protein A.Phosphatidyl inositol 3-kinase-like serine/threonine protein kinases (PIKKs) are required for DNA damage-induced phosphorylation of the 32 kDa subunit of replication protein A at threonine 21.DNA stimulates Mec1-mediated phosphorylation of replication protein A.Functions of human replication protein A (RPA): from DNA replication to DNA damage and stress responsesReplication protein A is an independent prognostic indicator with potential therapeutic implications in colon cancer.Regulatory functions of the N-terminal domain of the 70-kDa subunit of replication protein A (RPA)Human RPA phosphorylation by ATR stimulates DNA synthesis and prevents ssDNA accumulation during DNA-replication stressReplication protein A: directing traffic at the intersection of replication and repair.Targeted destruction of DNA replication protein Cdc6 by cell death pathways in mammals and yeast.Genetic analysis of the Replication Protein A large subunit family in Arabidopsis reveals unique and overlapping roles in DNA repair, meiosis and DNA replication.Ataxia-telangiectasia-mutated (ATM) is a T-antigen kinase that controls SV40 viral replication in vivo.Transcriptional activation of p21Waf1 contributes to suppression of HR by p53 in response to replication arrest induced by camptothecin.
P2860
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P2860
Adozelesin triggers DNA damage response pathways and arrests SV40 DNA replication through replication protein A inactivation.
description
2000 nî lūn-bûn
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2000 թուականի Յունուարին հրատարակուած գիտական յօդուած
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2000年の論文
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name
Adozelesin triggers DNA damage ...... cation protein A inactivation.
@ast
Adozelesin triggers DNA damage ...... cation protein A inactivation.
@en
type
label
Adozelesin triggers DNA damage ...... cation protein A inactivation.
@ast
Adozelesin triggers DNA damage ...... cation protein A inactivation.
@en
prefLabel
Adozelesin triggers DNA damage ...... cation protein A inactivation.
@ast
Adozelesin triggers DNA damage ...... cation protein A inactivation.
@en
P2093
P356
P1476
Adozelesin triggers DNA damage ...... cation protein A inactivation.
@en
P2093
P304
P356
10.1074/JBC.275.2.1391
P407
P577
2000-01-01T00:00:00Z