Site-directed recombination via bifunctional PNA-DNA conjugates.
about
Correction of a splice-site mutation in the beta-globin gene stimulated by triplex-forming peptide nucleic acidsTriplex-induced recombination and repair in the pyrimidine motif.In vivo correction of anaemia in β-thalassemic mice by γPNA-mediated gene editing with nanoparticle deliveryTargeted correction of a thalassemia-associated beta-globin mutation induced by pseudo-complementary peptide nucleic acidsImproved bioactivity of G-rich triplex-forming oligonucleotides containing modified guanine bases.Targeting and processing of site-specific DNA interstrand crosslinks.Peptide nucleic acid (PNA) binding-mediated gene regulation.Triplex technology in studies of DNA damage, DNA repair, and mutagenesisSelection of RNA aptamers that bind HIV-1 LTR DNA duplexes: strand invaders.Nanoparticles deliver triplex-forming PNAs for site-specific genomic recombination in CD34+ human hematopoietic progenitors.Applications of triple-stranded nucleic acid structures to DNA purification, detection and analysis.Targeted disruption of the CCR5 gene in human hematopoietic stem cells stimulated by peptide nucleic acidsTargeted gene modification of hematopoietic progenitor cells in mice following systemic administration of a PNA-peptide conjugateNanoparticles that deliver triplex-forming peptide nucleic acid molecules correct F508del CFTR in airway epitheliumTriplex structures induce DNA double strand breaks via replication fork collapse in NER deficient cells.Polypurine reverse-Hoogsteen (PPRH) oligonucleotides can form triplexes with their target sequences even under conditions where they fold into G-quadruplexes.Targeting DNA G-quadruplex structures with peptide nucleic acids.Triplex-forming peptide nucleic acids induce heritable elevations in gamma-globin expression in hematopoietic progenitor cells.The triple helix: 50 years later, the outcome.DNA triple helices: biological consequences and therapeutic potential.Systemic delivery of triplex-forming PNA and donor DNA by nanoparticles mediates site-specific genome editing of human hematopoietic cells in vivo.Peptide nucleic acid (PNA) binding and its effect on in vitro transcription in friedreich's ataxia triplet repeats.XPD-dependent activation of apoptosis in response to triplex-induced DNA damage.Repair of DNA lesions associated with triplex-forming oligonucleotides.DNA damage tolerance and a web of connections with DNA repair at Yale.Targeted gene conversion induced by triplex-directed psoralen interstrand crosslinks in mammalian cells.Site-specific Genome Editing in PBMCs With PLGA Nanoparticle-delivered PNAs Confers HIV-1 Resistance in Humanized Mice.Triplex-forming oligonucleotides targeting c-MYC potentiate the anti-tumor activity of gemcitabine in a mouse model of human cancer.Gene therapy in thalassemia and hemoglobinopathies.Polymer delivery systems for site-specific genome editingGenetic strategies for the treatment of sickle cell anaemia.Peptide nucleic acids: a review on recent patents and technology transfer.Chemical modifications of artificial restriction DNA cutter (ARCUT) to promote its in vivo and in vitro applications.Site-directed gene mutation at mixed sequence targets by psoralen-conjugated pseudo-complementary peptide nucleic acidsRepair of single-point mutations by polypurine reverse Hoogsteen hairpins.Conjugation of peptide nucleic acid with a pyrrole/imidazole polyamide to specifically recognize and cleave DNA.Extended target sequence specificity of PNA-minor-groove binder conjugates.Nanotechnology for delivery of peptide nucleic acids (PNAs)In Vivo Hematopoietic Stem Cell Transduction.Triplex-induced DNA damage response.
P2860
Q24652641-FB355273-B9A1-46D1-9018-B37241EAC789Q24810418-F29B3F04-DCAE-4B74-84C1-E84A9381CEABQ30051830-29A62F2B-6237-4D20-884C-41D973D65C59Q33429769-9D3C98E9-882F-4761-9EFF-7BD2CB31F7FCQ33584005-5AF1AA52-EA5D-404A-998A-C5D939B4878FQ33952673-D62CF26A-2871-4D9B-A0C3-C1C01A5DE77AQ33977872-7D565B05-6B10-4F9A-83C7-ED57B2D53248Q34179182-C3AFCE3B-722B-4E49-A917-B36A2CCC2FA1Q34401400-0F6DAFF6-921F-42EF-91BF-B85D3518620AQ34473283-2CB6782D-0B6D-4A9F-A0A8-99F07059061DQ35183658-31E7BB49-D788-47A2-AEE9-1927B2ED8173Q35244141-D23BB94C-5622-4E46-A255-0CF90B7C819DQ35665225-BC1ADEC4-4334-456D-BC17-E608A97454F1Q35781735-51A5B77C-27B7-4E07-BC48-46648A62530CQ36051360-F89BEFDF-98E8-4D70-AEC3-0B7876799CCFQ36244171-5BA479B8-9BA0-4646-9739-B40B181A424EQ36469629-85DE9589-391E-4B0F-A367-6851A66D25A9Q36659260-1B7C5C3B-CE86-4639-8E2F-745AE9AA0F37Q36868459-F11A49CF-9135-4704-B8D7-61E93A3A6506Q36982332-9ED91FF5-B7A9-405D-B77D-CCA5A4085A2DQ37019421-3203FC4E-596B-4777-8DFC-35588D08B3ABQ37149046-AC427BB0-167D-4832-B94E-7D1D7C4AF737Q37236749-445DE831-5050-453D-A713-8801AE1F2F17Q37346254-886C1648-E3B1-48D6-83B9-620A2D1A8BCFQ37358566-7DBD45CC-40E7-4D2B-97E8-378410806312Q37406060-B8AA7A4C-A3C4-4548-A60A-FB03BD00846AQ37467837-41827294-ED01-442F-BCA1-A25EC70FCC4EQ37732429-E09EC563-F2FE-4437-95D6-F22BC2936E18Q37854468-89B3432C-0339-424B-B3FF-89BCCA4C43F3Q37881210-D9E7A1CC-9B71-49AD-B281-DFA3FBCEF8C9Q37894826-2B4E2885-CFFC-43C0-B63C-54EAA8D084C6Q38176989-E3ADE933-ADCB-4A59-93F1-DBC388E466B7Q38294445-3598D9DB-A2E6-49B8-9FE3-FAD9A3F56258Q38296771-462701C4-2940-4025-BACD-4E86473595D6Q38304212-4CF7A2F1-D638-4927-8164-A3E809D749C2Q38311705-BBA9E7EA-CE49-44CA-A7DF-A195C65668FEQ38333216-E29DFEC8-78A2-453C-90B2-43BA17021679Q38699488-55524455-C415-4322-961B-69D456425534Q40045829-EA2B0D91-CF72-4AAB-970C-2CEFC19D7716Q41825339-1D38277F-284A-4384-BC60-A2AF0810AC52
P2860
Site-directed recombination via bifunctional PNA-DNA conjugates.
description
2002 nî lūn-bûn
@nan
2002 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
Site-directed recombination via bifunctional PNA-DNA conjugates.
@ast
Site-directed recombination via bifunctional PNA-DNA conjugates.
@en
type
label
Site-directed recombination via bifunctional PNA-DNA conjugates.
@ast
Site-directed recombination via bifunctional PNA-DNA conjugates.
@en
prefLabel
Site-directed recombination via bifunctional PNA-DNA conjugates.
@ast
Site-directed recombination via bifunctional PNA-DNA conjugates.
@en
P2093
P2860
P356
P1476
Site-directed recombination via bifunctional PNA-DNA conjugates.
@en
P2093
Faye A Rogers
Karen M Vasquez
Michael Egholm
Peter M Glazer
P2860
P304
16695-16700
P356
10.1073/PNAS.262556899
P407
P577
2002-12-02T00:00:00Z