G484S amino acid substitution in lanosterol 14-alpha demethylase (ERG11) is related to fluconazole resistance in a recurrent Cryptococcus neoformans clinical isolate.
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Multidrug resistance: an emerging crisisCryptococcus gattii infectionsTriclosan Demonstrates Synergic Effect with Amphotericin B and Fluconazole and Induces Apoptosis-Like Cell Death in Cryptococcus neoformansCharacterization of the chromosome 4 genes that affect fluconazole-induced disomy formation in Cryptococcus neoformansAntifungal Therapy: New Advances in the Understanding and Treatment of MycosisFungal cytochrome P450 sterol 14α-demethylase (CYP51) and azole resistance in plant and human pathogens.Genetic Basis of Antifungal Drug ResistanceA Population Genomics Approach to Assessing the Genetic Basis of Within-Host Microevolution Underlying Recurrent Cryptococcal Meningitis Infection.Genetic dissection of azole resistance mechanisms in Candida albicans and their validation in a mouse model of disseminated infectionCryptococcus neoformans and Cryptococcus gattii, the etiologic agents of cryptococcosis.Regulatory circuitry governing fungal development, drug resistance, and disease.Resistance to antifungals that target CYP51.Role of AFR1, an ABC transporter-encoding gene, in the in vivo response to fluconazole and virulence of Cryptococcus neoformans.Elucidating drug resistance in human fungal pathogens.Drug strategies targeting CYP51 in neglected tropical diseasesCryptococcus neoformans Yap1 is required for normal fluconazole and oxidative stress resistanceIdentification of a Cryptococcus neoformans cytochrome P450 lanosterol 14α-demethylase (Erg11) residue critical for differential susceptibility between fluconazole/voriconazole and itraconazole/posaconazole.The Investigational Drug VT-1129 Is a Highly Potent Inhibitor of Cryptococcus Species CYP51 but Only Weakly Inhibits the Human Enzyme.Resistance to voriconazole due to a G448S substitution in Aspergillus fumigatus in a patient with cerebral aspergillosis.Cryptococcus neoformans Yop1 , an endoplasmic reticulum curvature-stabilizing protein, participates with Sey1 in influencing fluconazole-induced disomy formationFluconazole Susceptibility in Cryptococcus gattii Is Dependent on the ABC Transporter Pdr11.Retrospective Study of Cryptococcal Meningitis With Elevated Minimum Inhibitory Concentration to Fluconazole in Immunocompromised Patients.Stress, drugs, and evolution: the role of cellular signaling in fungal drug resistanceEfflux-mediated antifungal drug resistance.Heteroresistance to fluconazole in Cryptococcus neoformans is intrinsic and associated with virulence.Azole heteroresistance in Cryptococcus neoformans: emergence of resistant clones with chromosomal disomy in the mouse brain during fluconazole treatmentCandida tropicalis antifungal cross-resistance is related to different azole target (Erg11p) modifications.Three-dimensional model of lanosterol 14 alpha-demethylase from Cryptococcus neoformans: active-site characterization and insights into azole binding.Fluconazole resistance in cryptococcal disease: emerging or intrinsic?Cryptococcosis: epidemiology, fungal resistance, and new alternatives for treatment.Mechanisms of Antifungal Drug Resistance.Impact of Resistance to Fluconazole on Virulence and Morphological Aspects of Cryptococcus neoformans and Cryptococcus gattii Isolates.Medically important fungi respond to azole drugs: an update.Regulation of ERG3, ERG6, and ERG11 Genes in Antifungal-Resistant isolates of Candida parapsilosisMolecular identification, antifungal resistance and virulence of Cryptococcus neoformans and Cryptococcus deneoformans isolated in Seville, Spain.An overview about the medical use of antifungals in Portugal in the last years.In vivo development of fluconazole resistance in serial Cryptococcus gattii isolates from a cat.Update on Antifungal Drug Resistance.Azole resistance in Cryptococcus gattii from the Pacific Northwest: Investigation of the role of ERG11.Novel mutations in CYP51B from Penicillium digitatum involved in prochloraz resistance.
P2860
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P2860
G484S amino acid substitution in lanosterol 14-alpha demethylase (ERG11) is related to fluconazole resistance in a recurrent Cryptococcus neoformans clinical isolate.
description
2003 nî lūn-bûn
@nan
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
2003年论文
@zh
2003年论文
@zh-cn
name
G484S amino acid substitution ...... s neoformans clinical isolate.
@en
type
label
G484S amino acid substitution ...... s neoformans clinical isolate.
@en
prefLabel
G484S amino acid substitution ...... s neoformans clinical isolate.
@en
P2093
P2860
P1476
G484S amino acid substitution ...... s neoformans clinical isolate.
@en
P2093
A Carolina Rodriguez
Angela Salve
Emilia Mellado
Graciela Davel
Juan L Rodriguez-Tudela
Laura Rodero
Liliana Guelfand
Manuel Cuenca-Estrella
Pedro Cahn
P2860
P304
P356
10.1128/AAC.47.11.3653-3656.2003
P407
P577
2003-11-01T00:00:00Z