G484S amino acid substitution in lanosterol 14-alpha demethylase (ERG11) is related to fluconazole resistance in a recurrent Cryptococcus neoformans clinical isolate. - Wikidata - wikimedia - TriplyDB

G484S amino acid substitution in lanosterol 14-alpha demethylase (ERG11) is related to fluconazole resistance in a recurrent Cryptococcus neoformans clinical isolate.

G484S amino acid substitution in lanosterol 14-alpha demethylase (ERG11) is related to fluconazole resistance in a recurrent Cryptococcus neoformans clinical isolate.

http://www.wikidata.org/entity/Q40130606

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Multidrug resistance: an emerging crisis Cryptococcus gattii infections Triclosan Demonstrates Synergic Effect with Amphotericin B and Fluconazole and Induces Apoptosis-Like Cell Death in Cryptococcus neoformans Characterization of the chromosome 4 genes that affect fluconazole-induced disomy formation in Cryptococcus neoformans Antifungal Therapy: New Advances in the Understanding and Treatment of Mycosis Fungal cytochrome P450 sterol 14α-demethylase (CYP51) and azole resistance in plant and human pathogens.Genetic Basis of Antifungal Drug Resistance A Population Genomics Approach to Assessing the Genetic Basis of Within-Host Microevolution Underlying Recurrent Cryptococcal Meningitis Infection.Genetic dissection of azole resistance mechanisms in Candida albicans and their validation in a mouse model of disseminated infection Cryptococcus neoformans and Cryptococcus gattii, the etiologic agents of cryptococcosis.Regulatory circuitry governing fungal development, drug resistance, and disease.Resistance to antifungals that target CYP51.Role of AFR1, an ABC transporter-encoding gene, in the in vivo response to fluconazole and virulence of Cryptococcus neoformans.Elucidating drug resistance in human fungal pathogens.Drug strategies targeting CYP51 in neglected tropical diseases Cryptococcus neoformans Yap1 is required for normal fluconazole and oxidative stress resistance Identification of a Cryptococcus neoformans cytochrome P450 lanosterol 14α-demethylase (Erg11) residue critical for differential susceptibility between fluconazole/voriconazole and itraconazole/posaconazole.The Investigational Drug VT-1129 Is a Highly Potent Inhibitor of Cryptococcus Species CYP51 but Only Weakly Inhibits the Human Enzyme.Resistance to voriconazole due to a G448S substitution in Aspergillus fumigatus in a patient with cerebral aspergillosis.Cryptococcus neoformans Yop1 , an endoplasmic reticulum curvature-stabilizing protein, participates with Sey1 in influencing fluconazole-induced disomy formation Fluconazole Susceptibility in Cryptococcus gattii Is Dependent on the ABC Transporter Pdr11.Retrospective Study of Cryptococcal Meningitis With Elevated Minimum Inhibitory Concentration to Fluconazole in Immunocompromised Patients.Stress, drugs, and evolution: the role of cellular signaling in fungal drug resistance Efflux-mediated antifungal drug resistance.Heteroresistance to fluconazole in Cryptococcus neoformans is intrinsic and associated with virulence.Azole heteroresistance in Cryptococcus neoformans: emergence of resistant clones with chromosomal disomy in the mouse brain during fluconazole treatment Candida tropicalis antifungal cross-resistance is related to different azole target (Erg11p) modifications.Three-dimensional model of lanosterol 14 alpha-demethylase from Cryptococcus neoformans: active-site characterization and insights into azole binding.Fluconazole resistance in cryptococcal disease: emerging or intrinsic?Cryptococcosis: epidemiology, fungal resistance, and new alternatives for treatment.Mechanisms of Antifungal Drug Resistance.Impact of Resistance to Fluconazole on Virulence and Morphological Aspects of Cryptococcus neoformans and Cryptococcus gattii Isolates.Medically important fungi respond to azole drugs: an update.Regulation of ERG3, ERG6, and ERG11 Genes in Antifungal-Resistant isolates of Candida parapsilosis Molecular identification, antifungal resistance and virulence of Cryptococcus neoformans and Cryptococcus deneoformans isolated in Seville, Spain.An overview about the medical use of antifungals in Portugal in the last years.In vivo development of fluconazole resistance in serial Cryptococcus gattii isolates from a cat.Update on Antifungal Drug Resistance.Azole resistance in Cryptococcus gattii from the Pacific Northwest: Investigation of the role of ERG11.Novel mutations in CYP51B from Penicillium digitatum involved in prochloraz resistance.

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P2860

G484S amino acid substitution in lanosterol 14-alpha demethylase (ERG11) is related to fluconazole resistance in a recurrent Cryptococcus neoformans clinical isolate.

http://www.wikidata.org/entity/Q40130606

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G484S amino acid substitution ...... s neoformans clinical isolate.

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G484S amino acid substitution ...... s neoformans clinical isolate.

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G484S amino acid substitution ...... s neoformans clinical isolate.

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AAC.47.11.3653-3656.2003

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Antimicrobial Agents and Chemotherapy

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G484S amino acid substitution ...... s neoformans clinical isolate.

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A Carolina Rodriguez

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Angela Salve

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Emilia Mellado

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Graciela Davel

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Juan L Rodriguez-Tudela

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Laura Rodero

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Liliana Guelfand

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Pedro Cahn

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P2860

CLUSTAL: a package for performing multiple sequence alignment on a microcomputer

Identification and characterization of a Cryptococcus neoformans ATP binding cassette (ABC) transporter-encoding gene, CnAFR1, involved in the resistance to fluconazole.

Amino acid substitutions in the cytochrome P-450 lanosterol 14alpha-demethylase (CYP51A1) from azole-resistant Candida albicans clinical isolates contribute to resistance to azole antifungal agents.

Multiple resistant phenotypes of Candida albicans coexist during episodes of oropharyngeal candidiasis in human immunodeficiency virus-infected patients

Influence of shaking on antifungal susceptibility testing of Cryptococcus neoformans: a comparison of the NCCLS standard M27A medium, buffered yeast nitrogen base, and RPMI-2% glucose.

Fluconazole tolerance in clinical isolates of Cryptococcus neoformans.

Development of azole resistance during fluconazole maintenance therapy for AIDS-associated cryptococcal disease.

Heterogeneous mechanisms of azole resistance in Candida albicans clinical isolates from an HIV-infected patient on continuous fluconazole therapy for oropharyngeal candidosis.

Drug resistance in Cryptococcus neoformans.

Increased fluconazole resistance of Cryptococcus neoformans isolated from a patient with AIDS and recurrent meningitis.

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