Effects of gamma-secretase inhibition on the amyloid beta isoform pattern in a mouse model of Alzheimer's disease.
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A window into the heterogeneity of human cerebrospinal fluid Aβ peptidesBACE1 inhibition induces a specific cerebrospinal fluid β-amyloid pattern that identifies drug effects in the central nervous systemPyroglutamate amyloid β (Aβ) aggravates behavioral deficits in transgenic amyloid mouse model for Alzheimer disease.A novel Abeta isoform pattern in CSF reflects gamma-secretase inhibition in Alzheimer diseaseEvaluation of the performance of novel Aβ isoforms as theragnostic markers in Alzheimer's disease: from the cell to the patient.The amyloid-β isoform pattern in cerebrospinal fluid in familial PSEN1 M139T- and L286P-associated Alzheimer's diseaseAccelerating drug discovery for Alzheimer's disease: best practices for preclinical animal studiesMass spectrometric characterization of brain amyloid beta isoform signatures in familial and sporadic Alzheimer's disease.Familial Presenilin Mutations and Sporadic Alzheimer's Disease Pathology: Is the Assumption of Biochemical Equivalence Justified?γ-Secretase associated with lipid rafts: multiple interactive pathways in the stepwise processing of β-carboxyl-terminal fragment.Changes in matrix metalloprotease activity and progranulin levels may contribute to the pathophysiological function of mutant leucine-rich repeat kinase 2.Aβ1-15/16 as a potential diagnostic marker in neurodegenerative diseases.Decrease in brain soluble amyloid precursor protein β (sAPPβ) in Alzheimer's disease cortex.Characterization of the brain β-amyloid isoform pattern at different ages of Tg2576 mice.
P2860
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P2860
Effects of gamma-secretase inhibition on the amyloid beta isoform pattern in a mouse model of Alzheimer's disease.
description
2009 nî lūn-bûn
@nan
2009 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
Effects of gamma-secretase inh ...... model of Alzheimer's disease.
@ast
Effects of gamma-secretase inh ...... model of Alzheimer's disease.
@en
type
label
Effects of gamma-secretase inh ...... model of Alzheimer's disease.
@ast
Effects of gamma-secretase inh ...... model of Alzheimer's disease.
@en
prefLabel
Effects of gamma-secretase inh ...... model of Alzheimer's disease.
@ast
Effects of gamma-secretase inh ...... model of Alzheimer's disease.
@en
P2093
P2860
P50
P356
P1476
Effects of gamma-secretase inh ...... model of Alzheimer's disease.
@en
P2093
Mikael K Gustavsson
Virginia M-Y Lee
P2860
P304
P356
10.1159/000264639
P50
P577
2009-12-03T00:00:00Z