Random peptide libraries displayed on adeno-associated virus to select for targeted gene therapy vectors.
about
Efficient transduction of vascular endothelial cells with recombinant adeno-associated virus serotype 1 and 5 vectorsAdeno-associated virus type 2 VP2 capsid protein is nonessential and can tolerate large peptide insertions at its N terminusA heterotypic bystander effect for tumor cell killing after adeno-associated virus/phage-mediated, vascular-targeted suicide gene transferDirected evolution of adeno-associated virus to an infectious respiratory virusAdeno-associated Virus as a Mammalian DNA VectorAdeno-associated virus at 50: a golden anniversary of discovery, research, and gene therapy success--a personal perspectiveStructure of AAV-DJ, a Retargeted Gene Therapy Vector: Cryo-Electron Microscopy at 4.5 Å ResolutionCardiac-targeted delivery of regulatory RNA molecules and genes for the treatment of heart failureE Pluribus Unum: 50 Years of Research, Millions of Viruses, and One Goal--Tailored Acceleration of AAV EvolutionCardiac AAV9-S100A1 gene therapy rescues post-ischemic heart failure in a preclinical large animal modelScreening of peptide libraries against protective antigen of Bacillus anthracis in a disposable microfluidic cartridgeApplying gene silencing technology to contraceptionTargeted gene silencing to induce permanent sterilityPhenotypic detection of clonotypic B cells in multiple myeloma by specific immunoglobulin ligands reveals their rarity in multiple myelomaFocal Delivery of AAV2/1-transgenes Into the Rat Brain by Localized Ultrasound-induced BBB Opening.A muscle-targeting peptide displayed on AAV2 improves muscle tropism on systemic delivery.Combinatorial peptide libraries: mining for cell-binding peptides.Development of a novel efficient method to construct an adenovirus library displaying random peptides on the fiber knob.Development of a ligand-directed approach to study the pathogenesis of invasive aspergillosis.Directed evolution of adeno-associated virus yields enhanced gene delivery vectors.Radiation-guided gene therapy of cancer.Neuronal affinity of a C7C loop peptide identified through phage display.Display technologies: application for the discovery of drug and gene delivery agents.Designer gene delivery vectors: molecular engineering and evolution of adeno-associated viral vectors for enhanced gene transferCombinatorial targeting of the macropinocytotic pathway in leukemia and lymphoma cells.In vitro and in vivo gene therapy vector evolution via multispecies interbreeding and retargeting of adeno-associated viruses.Enhanced nigrostriatal neuron-specific, long-term expression by using neural-specific promoters in combination with targeted gene transfer by modified helper virus-free HSV-1 vector particles.Directed evolution of a biterminal bacterial display scaffold enhances the display of diverse peptidesEngineering and selection of shuffled AAV genomes: a new strategy for producing targeted biological nanoparticles.Immunogenic display of diverse peptides on virus-like particles of RNA phage MS2Molecular engineering of viral gene delivery vehiclesApplication of a haematopoetic progenitor cell-targeted adeno-associated viral (AAV) vector established by selection of an AAV random peptide library on a leukaemia cell line.Oncolytic virus therapy for pancreatic cancer using the adenovirus library displaying random peptides on the fiber knob.A myocardium tropic adeno-associated virus (AAV) evolved by DNA shuffling and in vivo selection.Successful expansion but not complete restriction of tropism of adeno-associated virus by in vivo biopanning of random virus display peptide librariesGeneration of novel AAV variants by directed evolution for improved CFTR delivery to human ciliated airway epithelium.Molecular evolution of adeno-associated virus for enhanced glial gene delivery.Molecular signatures of disease brain endothelia provide new sites for CNS-directed enzyme therapyPotential of phage-displayed peptide library technology to identify functional targeting peptidesHeart-targeted adeno-associated viral vectors selected by in vivo biopanning of a random viral display peptide library.
P2860
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P2860
Random peptide libraries displayed on adeno-associated virus to select for targeted gene therapy vectors.
description
2003 nî lūn-bûn
@nan
2003 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
Random peptide libraries displ ...... targeted gene therapy vectors.
@ast
Random peptide libraries displ ...... targeted gene therapy vectors.
@en
type
label
Random peptide libraries displ ...... targeted gene therapy vectors.
@ast
Random peptide libraries displ ...... targeted gene therapy vectors.
@en
prefLabel
Random peptide libraries displ ...... targeted gene therapy vectors.
@ast
Random peptide libraries displ ...... targeted gene therapy vectors.
@en
P2093
P356
P1433
P1476
Random peptide libraries displ ...... targeted gene therapy vectors.
@en
P2093
Felix Kaul
Jürgen A Kleinschmidt
Martin Trepel
Matthew D Weitzman
Oliver J Müller
Wadih Arap
P2888
P304
P356
10.1038/NBT856
P577
2003-08-03T00:00:00Z