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Directed evolution of adeno-associated virus yields enhanced gene delivery vectors.

Directed evolution of adeno-associated virus yields enhanced gene delivery vectors.

http://www.wikidata.org/entity/Q33232270

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A novel adeno-associated viral variant for efficient and selective intravitreal transduction of rat Müller cells Directed evolution of adeno-associated virus to an infectious respiratory virus Adeno-associated Virus as a Mammalian DNA Vector Gene delivery strategies to promote spinal cord repair Oncolytic adenovirus-mediated therapy for prostate cancer Recombination in eukaryotic single stranded DNA viruses Electron microscopy analysis of a disaccharide analog complex reveals receptor interactions of adeno-associated virus The structure of AAVrh32.33, a novel gene delivery vector Non-Viral Nucleic Acid Delivery Strategies to the Central Nervous System E Pluribus Unum: 50 Years of Research, Millions of Viruses, and One Goal--Tailored Acceleration of AAV Evolution Structure of neurotropic adeno-associated virus AAVrh.8.Development of Patient-specific AAV Vectors After Neutralizing Antibody Selection for Enhanced Muscle Gene Transfer Quantitative 3D tracing of gene-delivery viral vectors in human cells and animal tissues.Directed evolution of a virus exclusively utilizing human epidermal growth factor receptor as the entry receptor.Organization of long-range inputs and outputs of frontal cortex for top-down control.SCHEMA computational design of virus capsid chimeras: calibrating how genome packaging, protection, and transduction correlate with calculated structural disruption.Designer gene delivery vectors: molecular engineering and evolution of adeno-associated viral vectors for enhanced gene transfer In vitro and in vivo gene therapy vector evolution via multispecies interbreeding and retargeting of adeno-associated viruses.Engineering and selection of shuffled AAV genomes: a new strategy for producing targeted biological nanoparticles.Molecular engineering of viral gene delivery vehicles DNA shuffling of adeno-associated virus yields functionally diverse viral progeny A myocardium tropic adeno-associated virus (AAV) evolved by DNA shuffling and in vivo selection.Successful expansion but not complete restriction of tropism of adeno-associated virus by in vivo biopanning of random virus display peptide libraries Generation of novel AAV variants by directed evolution for improved CFTR delivery to human ciliated airway epithelium.Directed evolution of adeno-associated virus for glioma cell transduction Molecular evolution of adeno-associated virus for enhanced glial gene delivery.Molecular signatures of disease brain endothelia provide new sites for CNS-directed enzyme therapy Directed evolution of a novel adeno-associated virus (AAV) vector that crosses the seizure-compromised blood-brain barrier (BBB).Sites in the AAV5 capsid tolerant to deletions and tandem duplications.Heart-targeted adeno-associated viral vectors selected by in vivo biopanning of a random viral display peptide library.Quantification of AAV particle titers by infrared fluorescence scanning of coomassie-stained sodium dodecyl sulfate-polyacrylamide gels.Limitations of encapsidation of recombinant self-complementary adeno-associated viral genomes in different serotype capsids and their quantitation AAV's anatomy: roadmap for optimizing vectors for translational success A viral over-expression system for the major malaria mosquito Anopheles gambiae.Systemic gene delivery to the central nervous system using Adeno-associated virus.An evolved adeno-associated viral variant enhances gene delivery and gene targeting in neural stem cells A NEW RECOMBINANT ADENO-ASSOCIATED VIRUS (AAV)-BASED RANDOM PEPTIDE DISPLAY LIBRARY SYSTEM: INFECTION-DEFECTIVE AAV1.9-3 AS A NOVEL DETARGETED PLATFORM FOR VECTOR EVOLUTION.Common gene therapy viral vectors do not efficiently penetrate sputum from cystic fibrosis patients.Naturally enveloped AAV vectors for shielding neutralizing antibodies and robust gene delivery in vivo.Novel random peptide libraries displayed on AAV serotype 9 for selection of endothelial cell-directed gene transfer vectors.

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P2860

Directed evolution of adeno-associated virus yields enhanced gene delivery vectors.

http://www.wikidata.org/entity/Q33232270

description

2006 nî lūn-bûn

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2006 թուականի Յունուարին հրատարակուած գիտական յօդուած

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2006 թվականի հունվարին հրատարակված գիտական հոդված

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2006年の論文

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2006年論文

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2006年論文

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2006年論文

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2006年論文

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2006年論文

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2006年论文

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name

Directed evolution of adeno-associated virus yields enhanced gene delivery vectors.

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Directed evolution of adeno-associated virus yields enhanced gene delivery vectors.

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Directed evolution of adeno-associated virus yields enhanced gene delivery vectors.

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Directed evolution of adeno-associated virus yields enhanced gene delivery vectors.

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Directed evolution of adeno-associated virus yields enhanced gene delivery vectors.

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Directed evolution of adeno-associated virus yields enhanced gene delivery vectors.

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P1433

Nature Biotechnology

P1476

Directed evolution of adeno-associated virus yields enhanced gene delivery vectors.

@en

P2093

Brian K Kaspar

http://www.w3.org/2001/XMLSchema#string

David V Schaffer

http://www.w3.org/2001/XMLSchema#string

James T Koerber

http://www.w3.org/2001/XMLSchema#string

Narendra Maheshri

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P2860

The atomic structure of adeno-associated virus (AAV-2), a vector for human gene therapy.

Novel adeno-associated viruses from rhesus monkeys as vectors for human gene therapy

Persistent expression of human clotting factor IX from mouse liver after intravenous injection of adeno-associated virus vectors

Rapid evolution of a protein in vitro by DNA shuffling

Sonic hedgehog regulates adult neural progenitor proliferation in vitro and in vivo

Quantitative analysis of the effect of the mutation frequency on the affinity maturation of single chain Fv antibodies.

Inverting enantioselectivity by directed evolution of hydantoinase for improved production of L-methionine.

Molecular breeding of viruses.

Monoclonal antibodies against the adeno-associated virus type 2 (AAV-2) capsid: epitope mapping and identification of capsid domains involved in AAV-2-cell interaction and neutralization of AAV-2 infection

Random peptide libraries displayed on adeno-associated virus to select for targeted gene therapy vectors.

P2888

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198-204

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scholarly article

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10.1038/NBT1182

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2

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24

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7344025

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16429148

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vector-borne disease

directed evolution