Human BRCA1 gene rescues the embryonic lethality of Brca1 mutant mice.

Human BRCA1 gene rescues the embryonic lethality of Brca1 mutant mice.

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http://www.wikidata.org/entity/Q30979035
BRCA1 associates with processive RNA polymerase IILong human CHGA flanking chromosome 14 sequence required for optimal BAC transgenic "rescue" of disease phenotypes in the mouse Chga knockout.Hypertension from targeted ablation of chromogranin A can be rescued by the human orthologModelling human regulatory variation in mouse: finding the function in genome-wide association studies and whole-genome sequencingMouse models of inherited cancer syndromesTransgenic and knockout mice models to reveal the functions of tumor suppressor genes.A simple two-step, 'hit and fix' method to generate subtle mutations in BACs using short denatured PCR fragmentsMouse models of BRCA1 and BRCA2 deficiency: past lessons, current understanding and future prospects.Large family with both parents affected by distinct BRCA1 mutations: implications for genetic testingBRCA1-deficient mammary tumor cells are dependent on EZH2 expression and sensitive to Polycomb Repressive Complex 2-inhibitor 3-deazaneplanocin A.Expression of human BRCA1 variants in mouse ES cells allows functional analysis of BRCA1 mutations.Breast cancer gene variants: separating the harmful from the harmless.Preclinical mouse models for BRCA1-associated breast cancer.Bridging the gap from genetic association to functional understanding: the next generation of mouse models of multiple sclerosis.BRCA1 and CtIP suppress long-tract gene conversion between sister chromatids.A targeted mouse Brca1 mutation removing the last BRCT repeat results in apoptosis and embryonic lethality at the headfold stage.Spatiotemporal dynamics of homologous recombination repair at single collapsed replication forks
P2860

Human BRCA1 gene rescues the embryonic lethality of Brca1 mutant mice.

Item
http://www.wikidata.org/entity/Q30979035
description
2001 nî lūn-bûn
@nan
2001 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年学术文章
@wuu
2001年学术文章
@zh-cn
2001年学术文章
@zh-hans
2001年学术文章
@zh-my
2001年学术文章
@zh-sg
2001年學術文章
@yue
name
Human BRCA1 gene rescues the embryonic lethality of Brca1 mutant mice.
@ast
Human BRCA1 gene rescues the embryonic lethality of Brca1 mutant mice.
@en
type
label
Human BRCA1 gene rescues the embryonic lethality of Brca1 mutant mice.
@ast
Human BRCA1 gene rescues the embryonic lethality of Brca1 mutant mice.
@en
prefLabel
Human BRCA1 gene rescues the embryonic lethality of Brca1 mutant mice.
@ast
Human BRCA1 gene rescues the embryonic lethality of Brca1 mutant mice.
@en
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Human BRCA1 gene rescues the embryonic lethality of Brca1 mutant mice.
@en
P2093
P2860
P304
P31
P356
10.1002/1526-968X(200102)29:2<72::AID-GENE1007>3.0.CO;2-B
P433
P478
P577
P698