The developmental pattern of Brca1 expression implies a role in differentiation of the breast and other tissues. - Wikidata - wikimedia - TriplyDB

The developmental pattern of Brca1 expression implies a role in differentiation of the breast and other tissues.

The developmental pattern of Brca1 expression implies a role in differentiation of the breast and other tissues.

http://www.wikidata.org/entity/Q34719803

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Expression of BRC repeats in breast cancer cells disrupts the BRCA2-Rad51 complex and leads to radiation hypersensitivity and loss of G(2)/M checkpoint control Negative Regulation of BRCA1 Gene Expression by HMGA1 Proteins Accounts for the Reduced BRCA1 Protein Levels in Sporadic Breast Carcinoma Steroid receptor RNA activator stimulates proliferation as well as apoptosis in vivo BRCA1 is secreted and exhibits properties of a granin BRCA1 is phosphorylated at serine 1497 in vivo at a cyclin-dependent kinase 2 phosphorylation site BRCA1 and BRCA2 proteins: roles in health and disease Breastfeeding and the risk of breast cancer in BRCA1 and BRCA2 mutation carriers Cell cycle-dependent colocalization of BARD1 and BRCA1 proteins in discrete nuclear domains BRCA1 inhibition of telomerase activity in cultured cells The BRCA2 gene product functionally interacts with p53 and RAD51 BRCA1 interacts with components of the histone deacetylase complex Increased cell survival by inhibition of BRCA1 using an antisense approach in an estrogen responsive ovarian carcinoma cell line Regulation of BRCA1 expression and its relationship to sporadic breast cancer Genomic analysis of early murine mammary gland development using novel probe-level algorithms Role of BRCA gene dysfunction in breast and ovarian cancer predisposition.BRCA2 mutation carriers, reproductive factors and breast cancer risk Heregulin induces phosphorylation of BRCA1 through phosphatidylinositol 3-Kinase/AKT in breast cancer cells A novel tricomplex of BRCA1, Nmi, and c-Myc inhibits c-Myc-induced human telomerase reverse transcriptase gene (hTERT) promoter activity in breast cancer c-Fos oncogene regulator Elk-1 interacts with BRCA1 splice variants BRCA1a/1b and enhances BRCA1a/1b-mediated growth suppression in breast cancer cells Timing of dietary estrogenic exposures and breast cancer risk The second BRCT domain of BRCA1 proteins interacts with p53 and stimulates transcription from the p21WAF1/CIP1 promoter Chromatin remodeling and histone modification in the conversion of oligodendrocyte precursors to neural stem cells Prepubertal physical activity up-regulates estrogen receptor beta, BRCA1 and p53 mRNA expression in the rat mammary gland Human BRCA1 gene rescues the embryonic lethality of Brca1 mutant mice.Computational expression deconvolution in a complex mammalian organ Germline mutations of BRCA1 gene exon 11 are not associated with platinum response neither with survival advantage in patients with primary ovarian cancer: understanding the clinical importance of one of the biggest human exons. A study of the Tumor The breast cancer susceptibility gene BRCA1 regulates progesterone receptor signaling in mammary epithelial cells.Mutation analysis of the BRCA1 gene in 23 families with cases of cancer of the breast, ovary, and multiple other sites Genetic control of extraembryonic cell lineages studied with tetraploid<-->diploid chimeric concepti.Low frequency of BRCA1 germline mutations in 45 German breast/ovarian cancer families HOXA9 regulates BRCA1 expression to modulate human breast tumor phenotype.Trp63 is regulated by STAT5 in mammary tissue and subject to differentiation in cancer.Role of the tumor suppressor gene Brca1 in genetic stability and mammary gland tumor formation.Transcriptional regulation of the base excision repair pathway by BRCA1 Growth retardation, DNA repair defects, and lack of spermatogenesis in BRCA1-deficient mice.Activated networking of platelet activating factor receptor and FAK/STAT1 induces malignant potential in BRCA1-mutant at-risk ovarian epithelium.Tumor suppressor BRCA1 is expressed in prostate cancer and controls insulin-like growth factor I receptor (IGF-IR) gene transcription in an androgen receptor-dependent manner.Lessons learned from BRCA1 and BRCA2.BRCA1 and prostate cancer.Breast cancer 1 (BrCa1) may be behind decreased lipogenesis in adipose tissue from obese subjects.

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P2860

The developmental pattern of Brca1 expression implies a role in differentiation of the breast and other tissues.

http://www.wikidata.org/entity/Q34719803

description

1995 nî lūn-bûn

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1995 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած

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1995 թվականի սեպտեմբերին հրատարակված գիտական հոդված

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1995年の論文

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1995年論文

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1995年論文

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1995年論文

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1995年論文

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1995年论文

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Abel KJ

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Chodosh LA

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Weber BL

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10.1038/NG0995-17

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