Direct inhibition of caspase 3 is dispensable for the anti-apoptotic activity of XIAP. - Wikidata - wikimedia - TriplyDB

Direct inhibition of caspase 3 is dispensable for the anti-apoptotic activity of XIAP.

Direct inhibition of caspase 3 is dispensable for the anti-apoptotic activity of XIAP.

http://www.wikidata.org/entity/Q30992809

about

Nrdp1-mediated degradation of the gigantic IAP, BRUCE, is a novel pathway for triggering apoptosis Inhibitor of apoptosis proteins and their relatives: IAPs and other BIRPs.Upstream regulatory role for XIAP in receptor-mediated apoptosis Human inhibitor of apoptosis proteins: why XIAP is the black sheep of the family The anti-apoptotic activity of XIAP is retained upon mutation of both the caspase 3- and caspase 9-interacting sites Ubiquitin-Mediated Regulation of Cell Death, Inflammation, and Defense of Homeostasis Versatile assays for high throughput screening for activators or inhibitors of intracellular proteases and their cellular regulators FAIM-L regulation of XIAP degradation modulates Synaptic Long-Term Depression and Axon Degeneration Regulation of PI3K/Akt dependent apoptotic markers during b virus infection of human and macaque fibroblasts.Dendroaspis natriuretic peptide induces the apoptosis of cardiac muscle cells.Modeling the effects of a Staphylococcal Enterotoxin B (SEB) on the apoptosis pathway.Src kinase phosphorylates Caspase-8 on Tyr380: a novel mechanism of apoptosis suppression Determination of cell survival by RING-mediated regulation of inhibitor of apoptosis (IAP) protein abundance Yeast and apoptosis.Fas death receptor signalling: roles of Bid and XIAP.The role of mitochondria in apoptosis*.DIAP2 functions as a mechanism-based regulator of drICE that contributes to the caspase activity threshold in living cells Targeting Inhibitor of Apoptosis Proteins Protects from Bleomycin-Induced Lung Fibrosis.Neuronal apoptosis inhibitory protein is overexpressed in patients with unfavorable prognostic factors in breast cancer Sex differences in XIAP cleavage after traumatic brain injury in the rat.Regulation of Apoptosis by Inhibitors of Apoptosis (IAPs)New insights into cancer-related proteins provided by the yeast model.Regulation of cell migration, invasion and metastasis by IAP proteins and their antagonists.Impact of inhibitor of apoptosis proteins on immune modulation and inflammation.IAPs and Cell Death.Proteasome inhibition results in TRAIL sensitization of primary keratinocytes by removing the resistance-mediating block of effector caspase maturation XIAP inhibits caspase-3 and -7 using two binding sites: evolutionarily conserved mechanism of IAPs.Mathematical modeling reveals threshold mechanism in CD95-induced apoptosis.Unlike Diablo/smac, Grim promotes global ubiquitination and specific degradation of X chromosome-linked inhibitor of apoptosis (XIAP) and neither cause apoptosis.Elevated XIAP expression alone does not confer chemoresistance.The Spodoptera frugiperda effector caspase Sf-caspase-1 becomes unstable following its activation.Intramitochondrial recruitment of endolysosomes mediates Smac degradation and constitutes a novel intrinsic apoptosis antagonizing function of XIAP E3 ligase.Characterization of beta-N-acetylglucosaminidase cleavage by caspase-3 during apoptosis.IAP proteins: sticking it to Smac.IAPs are functionally non-equivalent and regulate effector caspases through distinct mechanisms.XIAP inhibition of caspase-3 preserves its association with the Apaf-1 apoptosome and prevents CD95- and Bax-induced apoptosis.Delayed neuronal death after brain trauma involves p53-dependent inhibition of NF-kappaB transcriptional activity.The effect of postischemic hypothermia on apoptotic cell death in the neonatal rat brain.X-linked inhibitor of apoptosis protein expression after ischemic injury in the human and rat developing brain.The p35 relative, p49, inhibits mammalian and Drosophila caspases including DRONC and protects against apoptosis.

P2860

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P2860

Direct inhibition of caspase 3 is dispensable for the anti-apoptotic activity of XIAP.

http://www.wikidata.org/entity/Q30992809

description

2001 nî lūn-bûn

@nan

2001 թուականի Յունիսին հրատարակուած գիտական յօդուած

@hyw

2001 թվականի հունիսին հրատարակված գիտական հոդված

@hy

2001年の論文

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2001年学术文章

@wuu

2001年学术文章

@zh-cn

2001年学术文章

@zh-hans

2001年学术文章

@zh-my

2001年学术文章

@zh-sg

2001年學術文章

@yue

name

Direct inhibition of caspase 3 is dispensable for the anti-apoptotic activity of XIAP.

@ast

Direct inhibition of caspase 3 is dispensable for the anti-apoptotic activity of XIAP.

@en

type

label

Direct inhibition of caspase 3 is dispensable for the anti-apoptotic activity of XIAP.

@ast

Direct inhibition of caspase 3 is dispensable for the anti-apoptotic activity of XIAP.

@en

prefLabel

Direct inhibition of caspase 3 is dispensable for the anti-apoptotic activity of XIAP.

@ast

Direct inhibition of caspase 3 is dispensable for the anti-apoptotic activity of XIAP.

@en

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P1433

The EMBO Journal

P1476

Direct inhibition of caspase 3 is dispensable for the anti-apoptotic activity of XIAP

@en

P2093

A M Verhagen

http://www.w3.org/2001/XMLSchema#string

J Chew

http://www.w3.org/2001/XMLSchema#string

M Baca

http://www.w3.org/2001/XMLSchema#string

M Pakusch

http://www.w3.org/2001/XMLSchema#string

P2860

Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade

TAB1: an activator of the TAK1 MAPKKK in TGF-beta signal transduction

Suppression of apoptosis in mammalian cells by NAIP and a related family of IAP genes

X-linked IAP is a direct inhibitor of cell-death proteases

Involvement of MACH, a novel MORT1/FADD-interacting protease, in Fas/APO-1- and TNF receptor-induced cell death

The c-IAP-1 and c-IAP-2 proteins are direct inhibitors of specific caspases

XIAP, a cellular member of the inhibitor of apoptosis protein family, links the receptors to TAB1-TAK1 in the BMP signaling pathway

A conserved family of cellular genes related to the baculovirus iap gene and encoding apoptosis inhibitors

NMR structure and mutagenesis of the inhibitor-of-apoptosis protein XIAP

NMR structure and mutagenesis of the third Bir domain of the inhibitor of apoptosis protein XIAP

P304

3114-3123

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scholarly article

P356

10.1093/EMBOJ/20.12.3114

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P433

12

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P478

20

http://www.w3.org/2001/XMLSchema#string

P50

Catherine L. Day

Christine Hawkins

P577

2001-06-01T00:00:00Z

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P5875

11932485

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P698

11406588

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P921

apoptotic process

P932

150202

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