Integrating data on DNA copy number with gene expression levels and drug sensitivities in the NCI-60 cell line panel.
about
An integrative genomic and proteomic approach to chemosensitivity predictionPutative DNA/RNA helicase Schlafen-11 (SLFN11) sensitizes cancer cells to DNA-damaging agentsCancer Cell Line Panels Empower Genomics-Based Discovery of Precision Cancer MedicineThe consequences of chromosomal aneuploidy on the transcriptome of cancer cellsIn vitro human cell line models to predict clinical response to anticancer drugsUsing drug response data to identify molecular effectors, and molecular "omic" data to identify candidate drugs in cancerMultiple-platform data integration method with application to combined analysis of microarray and proteomic dataIntegrative analysis of proteomic signatures, mutations, and drug responsiveness in the NCI 60 cancer cell line setPharmacogenomic discovery using cell-based modelsGemcitabine and arabinosylcytosin pharmacogenomics: genome-wide association and drug response biomarkersIdentification of a predominant co-regulation among kinetochore genes, prospective regulatory elements, and association with genomic instabilityConsensus-phenotype integration of transcriptomic and metabolomic data implies a role for metabolism in the chemosensitivity of tumour cellsAn integrative genomic and transcriptomic analysis reveals potential targets associated with cell proliferation in uterine leiomyomasNCI-60 whole exome sequencing and pharmacological CellMiner analysesHigh resolution copy number variation data in the NCI-60 cancer cell lines from whole genome microarrays accessible through CellMinerDevelopment of a Drug-Response Modeling Framework to Identify Cell Line Derived Translational Biomarkers That Can Predict Treatment Outcome to Erlotinib or SorafenibPublic data and open source tools for multi-assay genomic investigation of diseaseExon array analyses across the NCI-60 reveal potential regulation of TOP1 by transcription pausing at guanosine quartets in the first intronInferences of drug responses in cancer cells from cancer genomic features and compound chemical and therapeutic propertiesA community effort to assess and improve drug sensitivity prediction algorithms.Flexible and accurate detection of genomic copy-number changes from aCGH.Derivation of induced pluripotent stem cells from orangutan skin fibroblasts.A Bayesian Graphical Model for Integrative Analysis of TCGA Data.MDP, a database linking drug response data to genomic information, identifies dasatinib and statins as a combinatorial strategy to inhibit YAP/TAZ in cancer cellsA modular approach for integrative analysis of large-scale gene-expression and drug-response data.Database of Trypanosoma cruzi repeated genes: 20,000 additional gene variantsGlobal associations between copy number and transcript mRNA microarray data: an empirical study.CellMiner: a relational database and query tool for the NCI-60 cancer cell lines.Integrative analysis of gene expression and copy number alterations using canonical correlation analysis.DNA fingerprinting of the NCI-60 cell line panel.Multifactorial regulation of E-cadherin expression: an integrative study.An integrated analysis of molecular aberrations in NCI-60 cell lines.The glutaminase activity of L-asparaginase is not required for anticancer activity against ASNS-negative cells.A multivariate approach to the integration of multi-omics datasetsIntegrated analysis of gene expression and copy number data on gene shaving using independent component analysismRNA and microRNA expression profiles of the NCI-60 integrated with drug activitiesAsparagine synthetase: a new potential biomarker in ovarian cancer.Integrated genomics of ovarian xenograft tumor progression and chemotherapy response.Asparagine synthetase is a predictive biomarker of L-asparaginase activity in ovarian cancer cell lines.Permissivity of the NCI-60 cancer cell lines to oncolytic Vaccinia Virus GLV-1h68
P2860
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P2860
Integrating data on DNA copy number with gene expression levels and drug sensitivities in the NCI-60 cell line panel.
description
2006 nî lūn-bûn
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2006 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
Integrating data on DNA copy n ...... in the NCI-60 cell line panel.
@ast
Integrating data on DNA copy n ...... in the NCI-60 cell line panel.
@en
type
label
Integrating data on DNA copy n ...... in the NCI-60 cell line panel.
@ast
Integrating data on DNA copy n ...... in the NCI-60 cell line panel.
@en
prefLabel
Integrating data on DNA copy n ...... in the NCI-60 cell line panel.
@ast
Integrating data on DNA copy n ...... in the NCI-60 cell line panel.
@en
P2093
P2860
P1476
Integrating data on DNA copy n ...... in the NCI-60 cell line panel.
@en
P2093
Anna Roschke
Colin Collins
Dominic A Scudiero
Fuad Gwadry
Giovanni Tonon
Hosein Kouros-Mehr
Ilan Kirsch
Jane Fridlyand
P2860
P304
P356
10.1158/1535-7163.MCT-05-0155
P577
2006-04-01T00:00:00Z