Asparagine synthetase is a predictive biomarker of L-asparaginase activity in ovarian cancer cell lines.
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In vitro human cell line models to predict clinical response to anticancer drugsIntegrative analysis of proteomic signatures, mutations, and drug responsiveness in the NCI 60 cancer cell line setDNA fingerprinting of the NCI-60 cell line panel.The glutaminase activity of L-asparaginase is not required for anticancer activity against ASNS-negative cells.Polymorphism in asparagine synthetase is associated with overall survival of hepatocellular carcinoma patients.Asparagine synthetase: a new potential biomarker in ovarian cancer.Targeted metabolomic analysis of amino acid response to L-asparaginase in adherent cellsA conserved glutamate controls the commitment to acyl-adenylate formation in asparagine synthetaseAsparagine synthetase: regulation by cell stress and involvement in tumor biologySystematically characterizing and prioritizing chemosensitivity related gene based on Gene Ontology and protein interaction network.Cell cycle-dependent recruitment of polycomb proteins to the ASNS promoter counteracts C/ebp-mediated transcriptional activation in Bombyx mori.Asparaginase induces apoptosis and cytoprotective autophagy in chronic myeloid leukemia cells.L-asparaginase inhibits invasive and angiogenic activity and induces autophagy in ovarian cancer.Asparagine synthetase is an independent predictor of surgical survival and a potential therapeutic target in hepatocellular carcinomaUnique proteome signature of post-chemotherapy ovarian cancer ascites-derived tumor cells.Metabolic Alterations Caused by KRAS Mutations in Colorectal Cancer Contribute to Cell Adaptation to Glutamine Depletion by Upregulation of Asparagine Synthetase.Optimized CGenFF force-field parameters for acylphosphate and N-phosphonosulfonimidoyl functional groups.A phase II clinical trial of polyethylene glycol-conjugated L-asparaginase in patients with advanced ovarian cancer: Early closure for safety.Cancer cell metabolism: one hallmark, many faces.Asparaginase in the treatment of non-ALL hematologic malignancies.Targeting asparagine and autophagy for pulmonary adenocarcinoma therapy.Asparagine promotes cancer cell proliferation through use as an amino acid exchange factor.Pharmacological inhibition of fatty-acid oxidation synergistically enhances the effect of l-asparaginase in childhood ALL cells.Knockdown of asparagine synthetase by RNAi suppresses cell growth in human melanoma cells and epidermoid carcinoma cells.Down-regulation of asparagine synthetase induces cell cycle arrest and inhibits cell proliferation of breast cancer.Asparagine depletion potentiates the cytotoxic effect of chemotherapy against brain tumors.Expression of asparagine synthetase predicts in vitro response to L-asparaginase in canine lymphoid cell lines.The GCN2-ATF4 pathway is critical for tumour cell survival and proliferation in response to nutrient deprivation.Amino Acid deprivation-induced expression of asparagine synthetase regulates the growth and survival of cultured silkworm cells.Asparagine synthetase: Function, structure, and role in disease.Loss of asparagine synthetase suppresses the growth of human lung cancer cells by arresting cell cycle at G0/G1 phase.
P2860
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P2860
Asparagine synthetase is a predictive biomarker of L-asparaginase activity in ovarian cancer cell lines.
description
2008 nî lūn-bûn
@nan
2008 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
Asparagine synthetase is a pre ...... in ovarian cancer cell lines.
@ast
Asparagine synthetase is a pre ...... in ovarian cancer cell lines.
@en
Asparagine synthetase is a pre ...... in ovarian cancer cell lines.
@nl
type
label
Asparagine synthetase is a pre ...... in ovarian cancer cell lines.
@ast
Asparagine synthetase is a pre ...... in ovarian cancer cell lines.
@en
Asparagine synthetase is a pre ...... in ovarian cancer cell lines.
@nl
prefLabel
Asparagine synthetase is a pre ...... in ovarian cancer cell lines.
@ast
Asparagine synthetase is a pre ...... in ovarian cancer cell lines.
@en
Asparagine synthetase is a pre ...... in ovarian cancer cell lines.
@nl
P2093
P2860
P1476
Asparagine synthetase is a pre ...... y in ovarian cancer cell lines
@en
P2093
Amy A Hutchinson
Elise C Kohn
Jenny Llamas
John N Weinstein
Laurent Ozbun
Michael J Birrer
Michele Gunsior
Paul K Goldsmith
P2860
P304
P356
10.1158/1535-7163.MCT-08-0589
P577
2008-10-01T00:00:00Z