Profound downregulation of the RNA editing enzyme ADAR2 in ALS spinal motor neurons.
about
RNA toxicity from the ALS/FTD C9ORF72 expansion is mitigated by antisense interventionADAR1, inosine and the immune sensing system: distinguishing self from non-selfRegulation of Ion Channel and Transporter Function Through RNA EditingAdenosine-to-inosine RNA editing and human diseaseRNA-binding proteins in neurodegeneration: Seq and you shall receiveGenomic analysis of ADAR1 binding and its involvement in multiple RNA processing pathwaysTranscript diversification in the nervous system: a to I RNA editing in CNS function and disease developmentFunctional interaction between FUS and SMN underlies SMA-like splicing changes in wild-type hFUS mice.Interferons, signal transduction pathways, and the central nervous system.A critical analysis of codon optimization in human therapeutics.The AMPA receptor antagonist perampanel robustly rescues amyotrophic lateral sclerosis (ALS) pathology in sporadic ALS model mice.Aberrant RNA homeostasis in amyotrophic lateral sclerosis: potential for new therapeutic targets?Down-regulation of the RNA editing enzyme ADAR2 contributes to RGC death in a mouse model of glaucoma.Decrease of mRNA Editing after Spinal Cord Injury is Caused by Down-regulation of ADAR2 that is Triggered by Inflammatory ResponseThe emerging role of RNA editing in plasticity.Chronic glutamate treatment selectively modulates AMPA RNA editing and ADAR expression and activity in primary cortical neurons.Dysregulated A to I RNA editing and non-coding RNAs in neurodegeneration.Activity-regulated RNA editing in select neuronal subfields in hippocampus.Reciprocal regulation of A-to-I RNA editing and the vertebrate nervous systemA-to-I RNA editing: effects on proteins key to neural excitabilityAMPA receptors as drug targets in neurological disease--advantages, caveats, and future outlook.RNA metabolism in ALS: when normal processes become pathological.Antisense oligonucleotide therapy for the treatment of C9ORF72 ALS/FTD diseases.RNA-binding proteins as molecular links between cancer and neurodegeneration.The Good and the Bad of Glutamate Receptor RNA Editing.Altered Intracellular Milieu of ADAR2-Deficient Motor Neurons in Amyotrophic Lateral SclerosisADAR RNA editing in human disease; more to it than meets the I.Calpain-dependent disruption of nucleo-cytoplasmic transport in ALS motor neurons.System xC- is a mediator of microglial function and its deletion slows symptoms in amyotrophic lateral sclerosis mice.Peripheral neuropathy in limbic encephalitis with anti-glutamate receptor antibodies: Case report and systematic literature review.Rescue of amyotrophic lateral sclerosis phenotype in a mouse model by intravenous AAV9-ADAR2 delivery to motor neurons.Novel miR-b2122 regulates several ALS-related RNA-binding proteins.Construction of a guide-RNA for site-directed RNA mutagenesis utilising intracellular A-to-I RNA editingEditing inducer elements increases A-to-I editing efficiency in the mammalian transcriptome.The evolution and adaptation of A-to-I RNA editing.SPRINT: an SNP-free toolkit for identifying RNA editing sites.ALS Associated Mutations in Matrin 3 Alter Protein-Protein Interactions and Impede mRNA Nuclear Export.Tertiary structural elements determine the extent and specificity of messenger RNA editing.RNA-editing enzymes ADAR1 and ADAR2 coordinately regulate the editing and expression of Ctn RNA.A role for calpain-dependent cleavage of TDP-43 in amyotrophic lateral sclerosis pathology.
P2860
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P2860
Profound downregulation of the RNA editing enzyme ADAR2 in ALS spinal motor neurons.
description
2011 nî lūn-bûn
@nan
2011 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Profound downregulation of the RNA editing enzyme ADAR2 in ALS spinal motor neurons.
@ast
Profound downregulation of the RNA editing enzyme ADAR2 in ALS spinal motor neurons.
@en
type
label
Profound downregulation of the RNA editing enzyme ADAR2 in ALS spinal motor neurons.
@ast
Profound downregulation of the RNA editing enzyme ADAR2 in ALS spinal motor neurons.
@en
prefLabel
Profound downregulation of the RNA editing enzyme ADAR2 in ALS spinal motor neurons.
@ast
Profound downregulation of the RNA editing enzyme ADAR2 in ALS spinal motor neurons.
@en
P2093
P1476
Profound downregulation of the RNA editing enzyme ADAR2 in ALS spinal motor neurons.
@en
P2093
Akiyoshi Kakita
Hitoshi Aizawa
Hitoshi Takahashi
Shoji Tsuji
Takenari Yamashita
Takuto Hideyama
P304
P356
10.1016/J.NBD.2011.12.033
P577
2011-12-28T00:00:00Z