about
Identification of sequences common to more than one therapeutic target to treat complex diseases: simulating the high variance in sequence interactivity evolved to modulate robust phenotypesCrystallographic studies of chemically modified nucleic acids: a backward glanceCrystal structure of tricyclo-DNA: an unusual compensatory change of two adjacent backbone torsion anglesTherapeutic Potential of Tricyclo-DNA antisense oligonucleotidesSilencing disease genes in the laboratory and the clinicEfficient SMN Rescue following Subcutaneous Tricyclo-DNA Antisense Oligonucleotide TreatmentStructure/affinity studies in the bicyclo-DNA series: Synthesis and properties of oligonucleotides containing bc(en)-T and iso-tricyclo-T nucleosides.Position-dependent effects on stability in tricyclo-DNA modified oligonucleotide duplexesImproving gene silencing of siRNAs via tricyclo-DNA modificationRNA Interference-Guided Targeting of Hepatitis C Virus Replication with Antisense Locked Nucleic Acid-Based Oligonucleotides Containing 8-oxo-dG Modifications.Biophysical studies of DNA modified with conformationally constrained nucleotides: comparison of 2'-exo (north) and 3'-exo (south) 'locked' templatesOligonucleotides and polyribonucleotides: a review of antiviral activity.Nuclear antisense effects in cyclophilin A pre-mRNA splicing by oligonucleotides: a comparison of tricyclo-DNA with LNADevelopment of multiexon skipping antisense oligonucleotide therapy for Duchenne muscular dystrophyConformationally rigid nucleoside probes help understand the role of sugar pucker and nucleobase orientation in the thrombin-binding aptamerGene-based therapies of neuromuscular disorders: an update and the pivotal role of patient organizations in their discovery and implementation.New developments in the use of gene therapy to treat Duchenne muscular dystrophy.Comparative studies of tricyclo-DNA- and LNA-containing oligonucleotides as inhibitors of HIV-1 gene expression.Antisense Oligonucleotide-Based Therapy for Neuromuscular Disease.Delivery of therapeutic RNA-cleaving oligodeoxyribonucleotides (deoxyribozymes): from cell culture studies to clinical trials.Functional correction in mouse models of muscular dystrophy using exon-skipping tricyclo-DNA oligomers.Efficacy and Safety Profile of Tricyclo-DNA Antisense Oligonucleotides in Duchenne Muscular Dystrophy Mouse ModelExploring Hoogsteen and reversed-Hoogsteen duplex and triplex formation with tricyclo-DNA purine sequences.yDNA versus yyDNA pyrimidines: computational analysis of the effects of unidirectional ring expansion on the preferred sugar-base orientation, hydrogen-bonding interactions and stacking abilities.Link between MHC Fiber Type and Restoration of Dystrophin Expression and Key Components of the DAPC by Tricyclo-DNA-Mediated Exon Skipping.Selection and Identification of Skeletal-Muscle-Targeted RNA Aptamers.The Use of Tricyclo-DNA Oligomers for the Treatment of Genetic Disorders.Synthesis and biochemical characterization of tricyclothymidine triphosphate (tc-TTP).
P2860
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P2860
description
2002 nî lūn-bûn
@nan
2002 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
Antisense properties of tricyclo-DNA
@ast
Antisense properties of tricyclo-DNA
@en
type
label
Antisense properties of tricyclo-DNA
@ast
Antisense properties of tricyclo-DNA
@en
prefLabel
Antisense properties of tricyclo-DNA
@ast
Antisense properties of tricyclo-DNA
@en
P2093
P2860
P356
P1476
Antisense properties of tricyclo-DNA
@en
P2093
Christian J Leumann
Daniel Schümperli
Dorte Renneberg
Emilie Bouliong
Ulrich Reber
P2860
P304
P356
10.1093/NAR/GKF412
P407
P577
2002-07-01T00:00:00Z