In vivo selection of combinatorial libraries and designed affinity maturation of polydactyl zinc finger transcription factors for ICAM-1 provides new insights into gene regulation.
about
Engineering protocells: prospects for self-assembly and nanoscale production-linesEpigenetic Editing: On the Verge of Reprogramming Gene Expression at WillInduction of stable drug resistance in human breast cancer cells using a combinatorial zinc finger transcription factor libraryGenetic reprogramming of tumor cells by zinc finger transcription factorsPositive selection of DNA-protein interactions in mammalian cells through phenotypic coupling with retrovirus production.Modular system for the construction of zinc-finger libraries and proteins.Epigenome editing by a CRISPR-Cas9-based acetyltransferase activates genes from promoters and enhancers.Synthetic zinc finger proteins: the advent of targeted gene regulation and genome modification technologies.Functional validation of putative tumor suppressor gene C13ORF18 in cervical cancer by Artificial Transcription Factors.Controlling gene networks and cell fate with precision-targeted DNA-binding proteins and small-molecule-based genome readers.Induced DNA demethylation by targeting Ten-Eleven Translocation 2 to the human ICAM-1 promoter.Inhibition of human immunodeficiency virus type 1 replication with artificial transcription factors targeting the highly conserved primer-binding site.Directed evolution of improved zinc finger methyltransferases.Targeted silencing of the oncogenic transcription factor SOX2 in breast cancerEpigenetic manipulation of gene expression: a toolkit for cell biologistsDrug-inducible and simultaneous regulation of endogenous genes by single-chain nuclear receptor-based zinc-finger transcription factor gene switches.Specific reactivation of latent HIV-1 with designer zinc-finger transcription factors targeting the HIV-1 5'-LTR promoter.Zinc finger transcription factors designed for bispecific coregulation of ErbB2 and ErbB3 receptors: insights into ErbB receptor biology.Exploring strategies for the design of artificial transcription factors: targeting sites proximal to known regulatory regions for the induction of gamma-globin expression and the treatment of sickle cell disease.Writing of H3K4Me3 overcomes epigenetic silencing in a sustained but context-dependent manner.Rational design of an estrogen receptor mutant with altered DNA-binding specificity.Upregulation of endogenous ICAM-1 reduces ovarian cancer cell growth in the absence of immune cells.Benzoate X receptor zinc-finger gene switches for drug-inducible regulation of transcription.Reprogramming cell fate with artificial transcription factors.Re-expressing Epigenetically Silenced Genes by Inducing DNA Demethylation Through Targeting of Ten-Eleven Translocation 2 to Any Given Genomic Locus.
P2860
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P2860
In vivo selection of combinatorial libraries and designed affinity maturation of polydactyl zinc finger transcription factors for ICAM-1 provides new insights into gene regulation.
description
2004 nî lūn-bûn
@nan
2004 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
name
In vivo selection of combinato ...... insights into gene regulation.
@ast
In vivo selection of combinato ...... insights into gene regulation.
@en
type
label
In vivo selection of combinato ...... insights into gene regulation.
@ast
In vivo selection of combinato ...... insights into gene regulation.
@en
prefLabel
In vivo selection of combinato ...... insights into gene regulation.
@ast
In vivo selection of combinato ...... insights into gene regulation.
@en
P2093
P1476
In vivo selection of combinato ...... insights into gene regulation.
@en
P2093
Carlos F Barbas
Laurent Magnenat
Pilar Blancafort
P304
P356
10.1016/J.JMB.2004.06.030
P407
P577
2004-08-01T00:00:00Z